FLUORIDE INDUCED TOXICITY ON AMINO ACID, DNA AND RNA OF RAT, RATTUS RATTUS (WISTAR)

Fluoride is a naturally occurring contaminant in the water and it is essential for normal maintenance of teeth and bones. However, prolonged exposure to high concentration of fluoride is found to be deleterious to teeth, bones, and other organs. In the present study, the effects of sodium fluoride i...

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Main Author: Dipali Pillewar
Format: Article in Journal/Newspaper
Language:unknown
Published: 2020
Subjects:
Sodium fluoride
Liver
DNA
RNA
Amino Acid
Zoology
Rattus rattus
Online Access:https://zenodo.org/record/3612329
https://doi.org/10.5281/zenodo.3612329
id ftzenodo:oai:zenodo.org:3612329
record_format openpolar
spelling ftzenodo:oai:zenodo.org:3612329 2023-05-15T18:05:12+02:00 FLUORIDE INDUCED TOXICITY ON AMINO ACID, DNA AND RNA OF RAT, RATTUS RATTUS (WISTAR) Dipali Pillewar 2020-01-19 https://zenodo.org/record/3612329 https://doi.org/10.5281/zenodo.3612329 unknown doi:10.5281/zenodo.3612328 https://zenodo.org/record/3612329 https://doi.org/10.5281/zenodo.3612329 oai:zenodo.org:3612329 info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode International Journal of Zoology and Applied Biosciences 4(6) 278-280 Sodium fluoride Liver DNA RNA Amino Acid Zoology info:eu-repo/semantics/article publication-article 2020 ftzenodo https://doi.org/10.5281/zenodo.361232910.5281/zenodo.3612328 2023-03-10T18:25:49Z Fluoride is a naturally occurring contaminant in the water and it is essential for normal maintenance of teeth and bones. However, prolonged exposure to high concentration of fluoride is found to be deleterious to teeth, bones, and other organs. In the present study, the effects of sodium fluoride induced toxicity in rat liver were evaluated. Twenty rats were divided into four experimental groups containing 5 rats each. 1st group was used for control and 2nd, 3rd and 4th groups were ingested with different concentrations of sodium fluoride water respectively for 56 days. The result of the present study was showed as significantly increased in total amino acid and free amino acid concentration along with a decreased in DNA and RNA content of the rat as compared to control. Article in Journal/Newspaper Rattus rattus Zenodo
institution Open Polar
collection Zenodo
op_collection_id ftzenodo
language unknown
topic Sodium fluoride
Liver
DNA
RNA
Amino Acid
Zoology
spellingShingle Sodium fluoride
Liver
DNA
RNA
Amino Acid
Zoology
Dipali Pillewar
FLUORIDE INDUCED TOXICITY ON AMINO ACID, DNA AND RNA OF RAT, RATTUS RATTUS (WISTAR)
topic_facet Sodium fluoride
Liver
DNA
RNA
Amino Acid
Zoology
description Fluoride is a naturally occurring contaminant in the water and it is essential for normal maintenance of teeth and bones. However, prolonged exposure to high concentration of fluoride is found to be deleterious to teeth, bones, and other organs. In the present study, the effects of sodium fluoride induced toxicity in rat liver were evaluated. Twenty rats were divided into four experimental groups containing 5 rats each. 1st group was used for control and 2nd, 3rd and 4th groups were ingested with different concentrations of sodium fluoride water respectively for 56 days. The result of the present study was showed as significantly increased in total amino acid and free amino acid concentration along with a decreased in DNA and RNA content of the rat as compared to control.
format Article in Journal/Newspaper
author Dipali Pillewar
author_facet Dipali Pillewar
author_sort Dipali Pillewar
title FLUORIDE INDUCED TOXICITY ON AMINO ACID, DNA AND RNA OF RAT, RATTUS RATTUS (WISTAR)
title_short FLUORIDE INDUCED TOXICITY ON AMINO ACID, DNA AND RNA OF RAT, RATTUS RATTUS (WISTAR)
title_full FLUORIDE INDUCED TOXICITY ON AMINO ACID, DNA AND RNA OF RAT, RATTUS RATTUS (WISTAR)
title_fullStr FLUORIDE INDUCED TOXICITY ON AMINO ACID, DNA AND RNA OF RAT, RATTUS RATTUS (WISTAR)
title_full_unstemmed FLUORIDE INDUCED TOXICITY ON AMINO ACID, DNA AND RNA OF RAT, RATTUS RATTUS (WISTAR)
title_sort fluoride induced toxicity on amino acid, dna and rna of rat, rattus rattus (wistar)
publishDate 2020
url https://zenodo.org/record/3612329
https://doi.org/10.5281/zenodo.3612329
genre Rattus rattus
genre_facet Rattus rattus
op_source International Journal of Zoology and Applied Biosciences 4(6) 278-280
op_relation doi:10.5281/zenodo.3612328
https://zenodo.org/record/3612329
https://doi.org/10.5281/zenodo.3612329
oai:zenodo.org:3612329
op_rights info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/4.0/legalcode
op_doi https://doi.org/10.5281/zenodo.361232910.5281/zenodo.3612328
_version_ 1766176656452485120

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