Blue Light and Temperature Actigraphy Measures Predicting Metabolic Health Are Linked to Melatonin Receptor Polymorphism
This study explores the relationship between the light features of the Arctic spring equinox and circadian rhythms, sleep and metabolic health. Residents (N = 62) provided week-long actigraphy measures, including light exposure, which were related to body mass index (BMI), leptin and cortisol. Lower...
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ftzenodo:oai:zenodo.org:12748919 2024-09-09T19:23:38+00:00 Blue Light and Temperature Actigraphy Measures Predicting Metabolic Health Are Linked to Melatonin Receptor Polymorphism Gubin, Denis Danilenko, Konstantin Stefani, Oliver Kolomeichuk, Sergey Markov, Alexander Petrov, Ivan Voronin, Kirill Mezhakova, Marina Borisenkov, Mikhail Shigabaeva, Aislu Yuzhakova, Natalya Lobkina, Svetlana Weinert, Dietmar Cornelissen, Germaine 2023-01-01 https://doi.org/10.5281/zenodo.12748919 unknown Zenodo https://www.mdpi.com/2079-7737/13/1/22 https://doi.org/10.3390/biology13010022 https://zenodo.org/communities/lory https://zenodo.org/communities/lory_hslu_t_und_a https://zenodo.org/communities/lory_hslu https://doi.org/10.5281/zenodo.12748918 https://doi.org/10.5281/zenodo.12748919 oai:zenodo.org:12748919 info:eu-repo/semantics/openAccess Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode Biology, 13(1), (2023-01-01) Light Arctic Metabolism info:eu-repo/semantics/article 2023 ftzenodo https://doi.org/10.5281/zenodo.1274891910.3390/biology1301002210.5281/zenodo.12748918 2024-07-27T07:14:39Z This study explores the relationship between the light features of the Arctic spring equinox and circadian rhythms, sleep and metabolic health. Residents (N = 62) provided week-long actigraphy measures, including light exposure, which were related to body mass index (BMI), leptin and cortisol. Lower wrist temperature (wT) and higher evening blue light exposure (BLE), expressed as a novel index, the nocturnal excess index (NEIbl), were the most sensitive actigraphy measures associated with BMI. A higher BMI was linked to nocturnal BLE within distinct time windows. These associations were present specifically in carriers of the MTNR1B rs10830963 G-allele. A larger wake-after-sleep onset (WASO), smaller 24 h amplitude and earlier phase of the activity rhythm were associated with higher leptin. Higher cortisol was associated with an earlier M10 onset of BLE and with our other novel index, the Daylight Deficit Index of blue light, DDIbl. We also found sex-, age- and population-dependent differences in the parametric and non-parametric indices of BLE, wT and physical activity, while there were no differences in any sleep characteristics. Overall, this study determined sensitive actigraphy markers of light exposure and wT predictive of metabolic health and showed that these markers are linked to melatonin receptor polymorphism. + ID der Publikation: hslu_107556 + Art des Beitrages: Wissenschaftliche Medien + Sprache: Englisch + Letzte Aktualisierung: 2024-07-16 10:46:29 Article in Journal/Newspaper Arctic Zenodo Arctic |
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Open Polar |
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Zenodo |
op_collection_id |
ftzenodo |
language |
unknown |
topic |
Light Arctic Metabolism |
spellingShingle |
Light Arctic Metabolism Gubin, Denis Danilenko, Konstantin Stefani, Oliver Kolomeichuk, Sergey Markov, Alexander Petrov, Ivan Voronin, Kirill Mezhakova, Marina Borisenkov, Mikhail Shigabaeva, Aislu Yuzhakova, Natalya Lobkina, Svetlana Weinert, Dietmar Cornelissen, Germaine Blue Light and Temperature Actigraphy Measures Predicting Metabolic Health Are Linked to Melatonin Receptor Polymorphism |
topic_facet |
Light Arctic Metabolism |
description |
This study explores the relationship between the light features of the Arctic spring equinox and circadian rhythms, sleep and metabolic health. Residents (N = 62) provided week-long actigraphy measures, including light exposure, which were related to body mass index (BMI), leptin and cortisol. Lower wrist temperature (wT) and higher evening blue light exposure (BLE), expressed as a novel index, the nocturnal excess index (NEIbl), were the most sensitive actigraphy measures associated with BMI. A higher BMI was linked to nocturnal BLE within distinct time windows. These associations were present specifically in carriers of the MTNR1B rs10830963 G-allele. A larger wake-after-sleep onset (WASO), smaller 24 h amplitude and earlier phase of the activity rhythm were associated with higher leptin. Higher cortisol was associated with an earlier M10 onset of BLE and with our other novel index, the Daylight Deficit Index of blue light, DDIbl. We also found sex-, age- and population-dependent differences in the parametric and non-parametric indices of BLE, wT and physical activity, while there were no differences in any sleep characteristics. Overall, this study determined sensitive actigraphy markers of light exposure and wT predictive of metabolic health and showed that these markers are linked to melatonin receptor polymorphism. + ID der Publikation: hslu_107556 + Art des Beitrages: Wissenschaftliche Medien + Sprache: Englisch + Letzte Aktualisierung: 2024-07-16 10:46:29 |
format |
Article in Journal/Newspaper |
author |
Gubin, Denis Danilenko, Konstantin Stefani, Oliver Kolomeichuk, Sergey Markov, Alexander Petrov, Ivan Voronin, Kirill Mezhakova, Marina Borisenkov, Mikhail Shigabaeva, Aislu Yuzhakova, Natalya Lobkina, Svetlana Weinert, Dietmar Cornelissen, Germaine |
author_facet |
Gubin, Denis Danilenko, Konstantin Stefani, Oliver Kolomeichuk, Sergey Markov, Alexander Petrov, Ivan Voronin, Kirill Mezhakova, Marina Borisenkov, Mikhail Shigabaeva, Aislu Yuzhakova, Natalya Lobkina, Svetlana Weinert, Dietmar Cornelissen, Germaine |
author_sort |
Gubin, Denis |
title |
Blue Light and Temperature Actigraphy Measures Predicting Metabolic Health Are Linked to Melatonin Receptor Polymorphism |
title_short |
Blue Light and Temperature Actigraphy Measures Predicting Metabolic Health Are Linked to Melatonin Receptor Polymorphism |
title_full |
Blue Light and Temperature Actigraphy Measures Predicting Metabolic Health Are Linked to Melatonin Receptor Polymorphism |
title_fullStr |
Blue Light and Temperature Actigraphy Measures Predicting Metabolic Health Are Linked to Melatonin Receptor Polymorphism |
title_full_unstemmed |
Blue Light and Temperature Actigraphy Measures Predicting Metabolic Health Are Linked to Melatonin Receptor Polymorphism |
title_sort |
blue light and temperature actigraphy measures predicting metabolic health are linked to melatonin receptor polymorphism |
publisher |
Zenodo |
publishDate |
2023 |
url |
https://doi.org/10.5281/zenodo.12748919 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Biology, 13(1), (2023-01-01) |
op_relation |
https://www.mdpi.com/2079-7737/13/1/22 https://doi.org/10.3390/biology13010022 https://zenodo.org/communities/lory https://zenodo.org/communities/lory_hslu_t_und_a https://zenodo.org/communities/lory_hslu https://doi.org/10.5281/zenodo.12748918 https://doi.org/10.5281/zenodo.12748919 oai:zenodo.org:12748919 |
op_rights |
info:eu-repo/semantics/openAccess Creative Commons Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/legalcode |
op_doi |
https://doi.org/10.5281/zenodo.1274891910.3390/biology1301002210.5281/zenodo.12748918 |
_version_ |
1809893623522656256 |