Fish Skin Graft as Wound Dressing to Provide Acceleration of Wound Healing: A Narrative Review

• Main Author: Bremi Surya Winata
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: Zenodo 2024
• Subjects: atlantic cod; Gadus morhua; North Atlantic
• Online Access: https://doi.org/10.5281/zenodo.10638447

Acellular fish skin grafts (FSGs) are tissue-based products derived from the minimally processed skin of the Atlantic cod (Gadus morhua). The FSG has a high amount of omega-3 fatty acids, which aid in the regeneration of tissues by promoting the growth of new blood vessels and tissue formation throughout the stages of wound healing known as proliferation and remodeling. FSG exhibits a higher degree of structural resemblance to human skin compared to antiviral-treated skin substitutes like amniotic membrane. Furthermore, there is no evidence of any prion, bacterial, or viral infections being transmissible from North-Atlantic cod to humans. The FSG undergoes proprietary processing that maintains the integrity and lipid composition of the skin. FSG is presently the sole acellular dermal matrix product that does not derive from mammalian tissues. This review will examine the efficacy of FSG as a wound dressing. Keywords:- Fish skin Graft, Wound Dressing, Regeneration.