Lacunar infarction in type 2 diabetes is associated with a elevated intracranial arterial pulsatility index
PURPOSE: The arterial pulsatility index (PI) is measured by transcranial Doppler ultrasonography (TCD) and is postulated to reflect the vascular resistance distal to the artery being examined. An increased PI of the intracranial artery is often reported with diabetes mellitus (DM), old age, hyperten...
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ftyonseiuniv:oai:ir.ymlib.yonsei.ac.kr:22282913/97546 2023-05-15T16:01:33+02:00 Lacunar infarction in type 2 diabetes is associated with a elevated intracranial arterial pulsatility index Kee-Oog Lee Kyung-Yul Lee Jong Sook Park Chul-Woo Ahn Seung-Yeob Lee Park, Jong Suk Ahn, Chul Woo Lee, Kyung Yul 2007 802~806 https://ir.ymlib.yonsei.ac.kr/handle/22282913/97546 https://doi.org/10.3349/ymj.2007.48.5.802 unknown YONSEI MEDICAL JOURNAL J02813 0513-5796 OAK-2007-01779 https://ir.ymlib.yonsei.ac.kr/handle/22282913/97546 doi:10.3349/ymj.2007.48.5.802 1976-2437 T200701321 YONSEI MEDICAL JOURNAL, Vol.48(5) : 802-806, 2007 CC BY-NC-ND 2.0 KR https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ free CC-BY-NC-ND T200701321.pdf Article 2007 ftyonseiuniv https://doi.org/10.3349/ymj.2007.48.5.802 2020-05-17T08:18:17Z PURPOSE: The arterial pulsatility index (PI) is measured by transcranial Doppler ultrasonography (TCD) and is postulated to reflect the vascular resistance distal to the artery being examined. An increased PI of the intracranial artery is often reported with diabetes mellitus (DM), old age, hypertension, intracranial hypertension, vascular dementia, and small artery disease. Microvascular complication of DM, which may contribute to cerebral infarction, involves the small perforating artery and may influence the PI of the proximal artery. MATERIALS AND METHODS: We performed a TCD examination in patients with type 2 DM with acute lacunar infarction (DML, n=35), type 2 DM without cerebral infarction (DMO, n=69), and in control cases with no DM or cerebral infarction (control group, n=41). We then compared the TCD findings among these groups. RESULTS: The PI was significantly higher in the DML and DMO groups than in the control group (1.05, 0.93, 0.73. respectively, for the right middle cerebral artery; 1.04, 0.90, 0.73, respectively, for the left middle cerebral artery; 0.97, 0.89, 0.70, respectively, for the basilar artery). The PI was also significantly higher in the DML group than in the DMO group for both middle cerebral arteries. The flow velocity was comparable among the three groups. CONCLUSION: The elevated PI of the intracranial arteries may reflect diabetic cerebral microvascular complications. The PI measurement using TCD may be a useful predictor of lacunar infarction in type 2 DM patients. open Article in Journal/Newspaper DML YUHSpace (Yonsei University Health System Repository) Yonsei Medical Journal 48 5 802 |
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YUHSpace (Yonsei University Health System Repository) |
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ftyonseiuniv |
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description |
PURPOSE: The arterial pulsatility index (PI) is measured by transcranial Doppler ultrasonography (TCD) and is postulated to reflect the vascular resistance distal to the artery being examined. An increased PI of the intracranial artery is often reported with diabetes mellitus (DM), old age, hypertension, intracranial hypertension, vascular dementia, and small artery disease. Microvascular complication of DM, which may contribute to cerebral infarction, involves the small perforating artery and may influence the PI of the proximal artery. MATERIALS AND METHODS: We performed a TCD examination in patients with type 2 DM with acute lacunar infarction (DML, n=35), type 2 DM without cerebral infarction (DMO, n=69), and in control cases with no DM or cerebral infarction (control group, n=41). We then compared the TCD findings among these groups. RESULTS: The PI was significantly higher in the DML and DMO groups than in the control group (1.05, 0.93, 0.73. respectively, for the right middle cerebral artery; 1.04, 0.90, 0.73, respectively, for the left middle cerebral artery; 0.97, 0.89, 0.70, respectively, for the basilar artery). The PI was also significantly higher in the DML group than in the DMO group for both middle cerebral arteries. The flow velocity was comparable among the three groups. CONCLUSION: The elevated PI of the intracranial arteries may reflect diabetic cerebral microvascular complications. The PI measurement using TCD may be a useful predictor of lacunar infarction in type 2 DM patients. open |
author2 |
Kee-Oog Lee Kyung-Yul Lee Jong Sook Park Chul-Woo Ahn Seung-Yeob Lee Park, Jong Suk Ahn, Chul Woo Lee, Kyung Yul |
format |
Article in Journal/Newspaper |
title |
Lacunar infarction in type 2 diabetes is associated with a elevated intracranial arterial pulsatility index |
spellingShingle |
Lacunar infarction in type 2 diabetes is associated with a elevated intracranial arterial pulsatility index |
title_short |
Lacunar infarction in type 2 diabetes is associated with a elevated intracranial arterial pulsatility index |
title_full |
Lacunar infarction in type 2 diabetes is associated with a elevated intracranial arterial pulsatility index |
title_fullStr |
Lacunar infarction in type 2 diabetes is associated with a elevated intracranial arterial pulsatility index |
title_full_unstemmed |
Lacunar infarction in type 2 diabetes is associated with a elevated intracranial arterial pulsatility index |
title_sort |
lacunar infarction in type 2 diabetes is associated with a elevated intracranial arterial pulsatility index |
publishDate |
2007 |
url |
https://ir.ymlib.yonsei.ac.kr/handle/22282913/97546 https://doi.org/10.3349/ymj.2007.48.5.802 |
genre |
DML |
genre_facet |
DML |
op_source |
T200701321.pdf |
op_relation |
YONSEI MEDICAL JOURNAL J02813 0513-5796 OAK-2007-01779 https://ir.ymlib.yonsei.ac.kr/handle/22282913/97546 doi:10.3349/ymj.2007.48.5.802 1976-2437 T200701321 YONSEI MEDICAL JOURNAL, Vol.48(5) : 802-806, 2007 |
op_rights |
CC BY-NC-ND 2.0 KR https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ free |
op_rightsnorm |
CC-BY-NC-ND |
op_doi |
https://doi.org/10.3349/ymj.2007.48.5.802 |
container_title |
Yonsei Medical Journal |
container_volume |
48 |
container_issue |
5 |
container_start_page |
802 |
_version_ |
1766397357874741248 |