Sweepstakes reproductive success via pervasive and recurrent selective sweeps
Highly fecund natural populations characterized by high early mortality abound, yet our knowledge about their recruitment dynamics is somewhat rudimentary. This knowledge gap has implications for our understanding of genetic variation, population connectivity, local adaptation, and the resilience of...
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eLife Sciences Publications Ltd.
2023
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Online Access: | https://wrap.warwick.ac.uk/172483/ https://wrap.warwick.ac.uk/172483/7/elife-80781-v1.pdf https://wrap.warwick.ac.uk/172483/1/sweepstakes_selection_eLife_clean_final.pdf https://doi.org/10.7554/eLife.80781 |
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ftuwarwick:oai:wrap.warwick.ac.uk:172483 2024-04-21T07:56:46+00:00 Sweepstakes reproductive success via pervasive and recurrent selective sweeps Árnason, Einar Koskela, Jere Halldórsdóttir, Katrin Eldon, Bjarki 2023-02-20 application/pdf https://wrap.warwick.ac.uk/172483/ https://wrap.warwick.ac.uk/172483/7/elife-80781-v1.pdf https://wrap.warwick.ac.uk/172483/1/sweepstakes_selection_eLife_clean_final.pdf https://doi.org/10.7554/eLife.80781 unknown eLife Sciences Publications Ltd. https://wrap.warwick.ac.uk/172483/7/elife-80781-v1.pdf https://wrap.warwick.ac.uk/172483/1/sweepstakes_selection_eLife_clean_final.pdf Árnason, Einar, Koskela, Jere, Halldórsdóttir, Katrin and Eldon, Bjarki (2023) Sweepstakes reproductive success via pervasive and recurrent selective sweeps. eLife, 12 . e80781. doi:10.7554/eLife.80781 <http://dx.doi.org/10.7554/eLife.80781> ISSN 2050-084X. Journal Article NonPeerReviewed 2023 ftuwarwick https://doi.org/10.7554/eLife.80781 2024-03-27T15:40:22Z Highly fecund natural populations characterized by high early mortality abound, yet our knowledge about their recruitment dynamics is somewhat rudimentary. This knowledge gap has implications for our understanding of genetic variation, population connectivity, local adaptation, and the resilience of highly fecund populations. The concept of sweepstakes reproductive success, which posits a considerable variance and skew in individual reproductive output, is key to understanding the distribution of individual reproductive success. However, it still needs to be determined whether highly fecund organisms reproduce through sweepstakes and, if they do, the relative roles of neutral and selective sweepstakes. Here we use coalescent-based statistical analysis of population genomic data to show that selective sweepstakes likely explain recruitment dynamics in the highly fecund Atlantic cod. We show that the Kingman coalescent (modeling no sweepstakes) and the Xi-Beta coalescent (modeling random sweepstakes), including complex demography and background selection, do not provide an adequate fit for the data. The Durrett-Schweinsberg coalescent, in which selective sweepstakes result from recurrent and pervasive selective sweeps of new mutations, offers greater explanatory power. Our results show that models of sweepstakes reproduction and multiple-merger coalescents are relevant and necessary for understanding genetic diversity in highly fecund natural populations. These findings have fundamental implications for understanding the recruitment variation of fish stocks and general evolutionary genomics of high-fecundity organisms. Article in Journal/Newspaper atlantic cod The University of Warwick: WRAP - Warwick Research Archive Portal eLife 12 |
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The University of Warwick: WRAP - Warwick Research Archive Portal |
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description |
Highly fecund natural populations characterized by high early mortality abound, yet our knowledge about their recruitment dynamics is somewhat rudimentary. This knowledge gap has implications for our understanding of genetic variation, population connectivity, local adaptation, and the resilience of highly fecund populations. The concept of sweepstakes reproductive success, which posits a considerable variance and skew in individual reproductive output, is key to understanding the distribution of individual reproductive success. However, it still needs to be determined whether highly fecund organisms reproduce through sweepstakes and, if they do, the relative roles of neutral and selective sweepstakes. Here we use coalescent-based statistical analysis of population genomic data to show that selective sweepstakes likely explain recruitment dynamics in the highly fecund Atlantic cod. We show that the Kingman coalescent (modeling no sweepstakes) and the Xi-Beta coalescent (modeling random sweepstakes), including complex demography and background selection, do not provide an adequate fit for the data. The Durrett-Schweinsberg coalescent, in which selective sweepstakes result from recurrent and pervasive selective sweeps of new mutations, offers greater explanatory power. Our results show that models of sweepstakes reproduction and multiple-merger coalescents are relevant and necessary for understanding genetic diversity in highly fecund natural populations. These findings have fundamental implications for understanding the recruitment variation of fish stocks and general evolutionary genomics of high-fecundity organisms. |
format |
Article in Journal/Newspaper |
author |
Árnason, Einar Koskela, Jere Halldórsdóttir, Katrin Eldon, Bjarki |
spellingShingle |
Árnason, Einar Koskela, Jere Halldórsdóttir, Katrin Eldon, Bjarki Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
author_facet |
Árnason, Einar Koskela, Jere Halldórsdóttir, Katrin Eldon, Bjarki |
author_sort |
Árnason, Einar |
title |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_short |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_full |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_fullStr |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_full_unstemmed |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_sort |
sweepstakes reproductive success via pervasive and recurrent selective sweeps |
publisher |
eLife Sciences Publications Ltd. |
publishDate |
2023 |
url |
https://wrap.warwick.ac.uk/172483/ https://wrap.warwick.ac.uk/172483/7/elife-80781-v1.pdf https://wrap.warwick.ac.uk/172483/1/sweepstakes_selection_eLife_clean_final.pdf https://doi.org/10.7554/eLife.80781 |
genre |
atlantic cod |
genre_facet |
atlantic cod |
op_relation |
https://wrap.warwick.ac.uk/172483/7/elife-80781-v1.pdf https://wrap.warwick.ac.uk/172483/1/sweepstakes_selection_eLife_clean_final.pdf Árnason, Einar, Koskela, Jere, Halldórsdóttir, Katrin and Eldon, Bjarki (2023) Sweepstakes reproductive success via pervasive and recurrent selective sweeps. eLife, 12 . e80781. doi:10.7554/eLife.80781 <http://dx.doi.org/10.7554/eLife.80781> ISSN 2050-084X. |
op_doi |
https://doi.org/10.7554/eLife.80781 |
container_title |
eLife |
container_volume |
12 |
_version_ |
1796938648829034496 |