Rethinking dog domestication by integrating genetics, archeology, and biogeography
The dog was the first domesticated animal but it remains uncertain when the domestication process began and whether it occurred just once or multiple times across the Northern Hemisphere. To ascertain the value of modern genetic data to elucidate the origins of dog domestication, we analyzed 49,024...
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ftuvicpubl:oai:dspace.library.uvic.ca:1828/8411 2023-05-15T15:51:10+02:00 Rethinking dog domestication by integrating genetics, archeology, and biogeography Larson, Greger Karlsson, Elinor K. Perri, Angela Webster, Matthew T. Ho, Simon Y. W. Peters, Joris Stahl, Peter W. Piper, Philip J. Lingaas, Frode Fredholm, Merete Comstock, Kenine E. Modiano, Jamie F. Schelling, Claude Agoulnik, Alexander I. Leegwater, Peter A. Dobney, Keith Vigne, Jean-Denis Vila, Carles Andersson, Leif Lindblad-Toh, Kerstin 2012 application/pdf http://www.pnas.org/cgi/doi/10.1073/pnas.1203005109 https://dspace.library.uvic.ca//handle/1828/8411 en eng Proceedings of the National Academy of Sciences of the United States of America (PNAS) Larson, G., Karlsson, E.K., Perri, A., Webster, M.T., Ho, S.Y.W., Peters, J., … Lindblad- Toh, K. (2012). Rethinking dog domestication by integrating genetics, archeology, and biogeography. Proceedings of the National Academy of Sciences of the United States of America, (109), 8878-8883. doi:10.1073/pnas.1203005109 http://www.pnas.org/cgi/doi/10.1073/pnas.1203005109 https://dspace.library.uvic.ca//handle/1828/8411 genomics phylogeography Article 2012 ftuvicpubl https://doi.org/10.1073/pnas.1203005109 2022-05-19T06:14:08Z The dog was the first domesticated animal but it remains uncertain when the domestication process began and whether it occurred just once or multiple times across the Northern Hemisphere. To ascertain the value of modern genetic data to elucidate the origins of dog domestication, we analyzed 49,024 autosomal SNPs in 1,375 dogs (representing 35 breeds) and 19 wolves. After combining our data with previously published data, we contrasted the genetic signatures of 121 breeds with a worldwide archeological assessment of the earliest dog remains. Correlating the earliest archeological dogs with the geographic locations of 14 so-called “ancient” breeds (defined by their genetic differentiation) resulted in a counterintuitive pattern. First, none of the ancient breeds derive from regions where the oldest archeological remains have been found. Second, three of the ancient breeds (Basenjis, Dingoes, and New Guinea Singing Dogs) come from regions outside the natural range of Canis lupus (the dog’s wild ancestor) and where dogs were introduced more than 10,000 y after domestication. These results demonstrate that the unifying characteristic among all genetically distinct so-called ancient breeds is a lack of recent admixture with other breeds likely facilitated by geographic and cultural isolation. Furthermore, these genetically distinct ancient breeds only appear so because of their relative isolation, suggesting that studies of modern breeds have yet to shed light on dog origins. We conclude by assessing the limitations of past studies and how next-generation sequencing of modern and ancient individuals may unravel the history of dog domestication. G.L. is currently a Research Councils United Kingdom Academic Fellow and was supported by a European Molecular Biology Organization postdoctoral fellowship; K.L.-T. is a European Young Investigator award recipient funded by the European Science Foundation, and was supported by grants from the Swedish Research Council; and A.P. was supported by the British Association for ... Article in Journal/Newspaper Canis lupus University of Victoria (Canada): UVicDSpace Proceedings of the National Academy of Sciences 109 23 8878 8883 |
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University of Victoria (Canada): UVicDSpace |
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ftuvicpubl |
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English |
topic |
genomics phylogeography |
spellingShingle |
genomics phylogeography Larson, Greger Karlsson, Elinor K. Perri, Angela Webster, Matthew T. Ho, Simon Y. W. Peters, Joris Stahl, Peter W. Piper, Philip J. Lingaas, Frode Fredholm, Merete Comstock, Kenine E. Modiano, Jamie F. Schelling, Claude Agoulnik, Alexander I. Leegwater, Peter A. Dobney, Keith Vigne, Jean-Denis Vila, Carles Andersson, Leif Lindblad-Toh, Kerstin Rethinking dog domestication by integrating genetics, archeology, and biogeography |
topic_facet |
genomics phylogeography |
description |
The dog was the first domesticated animal but it remains uncertain when the domestication process began and whether it occurred just once or multiple times across the Northern Hemisphere. To ascertain the value of modern genetic data to elucidate the origins of dog domestication, we analyzed 49,024 autosomal SNPs in 1,375 dogs (representing 35 breeds) and 19 wolves. After combining our data with previously published data, we contrasted the genetic signatures of 121 breeds with a worldwide archeological assessment of the earliest dog remains. Correlating the earliest archeological dogs with the geographic locations of 14 so-called “ancient” breeds (defined by their genetic differentiation) resulted in a counterintuitive pattern. First, none of the ancient breeds derive from regions where the oldest archeological remains have been found. Second, three of the ancient breeds (Basenjis, Dingoes, and New Guinea Singing Dogs) come from regions outside the natural range of Canis lupus (the dog’s wild ancestor) and where dogs were introduced more than 10,000 y after domestication. These results demonstrate that the unifying characteristic among all genetically distinct so-called ancient breeds is a lack of recent admixture with other breeds likely facilitated by geographic and cultural isolation. Furthermore, these genetically distinct ancient breeds only appear so because of their relative isolation, suggesting that studies of modern breeds have yet to shed light on dog origins. We conclude by assessing the limitations of past studies and how next-generation sequencing of modern and ancient individuals may unravel the history of dog domestication. G.L. is currently a Research Councils United Kingdom Academic Fellow and was supported by a European Molecular Biology Organization postdoctoral fellowship; K.L.-T. is a European Young Investigator award recipient funded by the European Science Foundation, and was supported by grants from the Swedish Research Council; and A.P. was supported by the British Association for ... |
format |
Article in Journal/Newspaper |
author |
Larson, Greger Karlsson, Elinor K. Perri, Angela Webster, Matthew T. Ho, Simon Y. W. Peters, Joris Stahl, Peter W. Piper, Philip J. Lingaas, Frode Fredholm, Merete Comstock, Kenine E. Modiano, Jamie F. Schelling, Claude Agoulnik, Alexander I. Leegwater, Peter A. Dobney, Keith Vigne, Jean-Denis Vila, Carles Andersson, Leif Lindblad-Toh, Kerstin |
author_facet |
Larson, Greger Karlsson, Elinor K. Perri, Angela Webster, Matthew T. Ho, Simon Y. W. Peters, Joris Stahl, Peter W. Piper, Philip J. Lingaas, Frode Fredholm, Merete Comstock, Kenine E. Modiano, Jamie F. Schelling, Claude Agoulnik, Alexander I. Leegwater, Peter A. Dobney, Keith Vigne, Jean-Denis Vila, Carles Andersson, Leif Lindblad-Toh, Kerstin |
author_sort |
Larson, Greger |
title |
Rethinking dog domestication by integrating genetics, archeology, and biogeography |
title_short |
Rethinking dog domestication by integrating genetics, archeology, and biogeography |
title_full |
Rethinking dog domestication by integrating genetics, archeology, and biogeography |
title_fullStr |
Rethinking dog domestication by integrating genetics, archeology, and biogeography |
title_full_unstemmed |
Rethinking dog domestication by integrating genetics, archeology, and biogeography |
title_sort |
rethinking dog domestication by integrating genetics, archeology, and biogeography |
publisher |
Proceedings of the National Academy of Sciences of the United States of America (PNAS) |
publishDate |
2012 |
url |
http://www.pnas.org/cgi/doi/10.1073/pnas.1203005109 https://dspace.library.uvic.ca//handle/1828/8411 |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_relation |
Larson, G., Karlsson, E.K., Perri, A., Webster, M.T., Ho, S.Y.W., Peters, J., … Lindblad- Toh, K. (2012). Rethinking dog domestication by integrating genetics, archeology, and biogeography. Proceedings of the National Academy of Sciences of the United States of America, (109), 8878-8883. doi:10.1073/pnas.1203005109 http://www.pnas.org/cgi/doi/10.1073/pnas.1203005109 https://dspace.library.uvic.ca//handle/1828/8411 |
op_doi |
https://doi.org/10.1073/pnas.1203005109 |
container_title |
Proceedings of the National Academy of Sciences |
container_volume |
109 |
container_issue |
23 |
container_start_page |
8878 |
op_container_end_page |
8883 |
_version_ |
1766386225588994048 |