Type II Diabetes and KCNQ1 mutations in First Nations people of northern British Columbia

• Main Author: Polanco Paniagua, Fernando de Jesus
• Other Authors: Arbour, Laura, Reading, Jeffrey Lawrence
• Format: Thesis
• Language: English
• Published: 2012
• Subjects: Type 2 Diabetes; Human Genetics; First Nations People of BC; British Columbia; Canada; Iks; First Nations
• Online Access: http://hdl.handle.net/1828/4245

Background: A novel mutation (V205M) within the KCNQ1 gene was previously delineated and confirmed to predispose to long QT syndrome (LQTS) in a First Nations community in Northern British Columbia (Gitxsan). LQTS is an autosomal dominant genetic disease that is named for the elongation of the ECG (...