No Serological Evidence that Harbour Porpoises Are Additional Hosts of Influenza B Viruses

Influenza A and B viruses circulate among humans causing epidemics almost annually. While various hosts for influenza A viruses exist, influenza B viruses have been detected only in humans and seals. However, recurrent infections of seals in Dutch coastal waters with influenza B viruses that are ant...

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Published in:PLoS ONE
Main Authors: Bodewes, Rogier, van de Bildt, Marco, Elk, Niels, Bunskoek, PE, van de Vijver, David, Smits, Saskia, Osterhaus, Ab, Kuiken, Thijs
Format: Article in Journal/Newspaper
Language:unknown
Published: 2014
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Online Access:https://pure.eur.nl/en/publications/fd68ffc7-2c56-4c58-8980-b51612f9aff6
https://doi.org/10.1371/journal.pone.0089058
https://pure.eur.nl/ws/files/47591354/journal.pone.0089058.pdf
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spelling fturottercrispub:oai:pure.eur.nl:publications/fd68ffc7-2c56-4c58-8980-b51612f9aff6 2023-05-15T17:59:13+02:00 No Serological Evidence that Harbour Porpoises Are Additional Hosts of Influenza B Viruses Bodewes, Rogier van de Bildt, Marco Elk, Niels Bunskoek, PE van de Vijver, David Smits, Saskia Osterhaus, Ab Kuiken, Thijs 2014 application/pdf https://pure.eur.nl/en/publications/fd68ffc7-2c56-4c58-8980-b51612f9aff6 https://doi.org/10.1371/journal.pone.0089058 https://pure.eur.nl/ws/files/47591354/journal.pone.0089058.pdf und unknown info:eu-repo/semantics/openAccess Bodewes , R , van de Bildt , M , Elk , N , Bunskoek , PE , van de Vijver , D , Smits , S , Osterhaus , A & Kuiken , T 2014 , ' No Serological Evidence that Harbour Porpoises Are Additional Hosts of Influenza B Viruses ' , PLoS One (print) , vol. 9 , no. 2 . https://doi.org/10.1371/journal.pone.0089058 article 2014 fturottercrispub https://doi.org/10.1371/journal.pone.0089058 2022-06-26T06:07:39Z Influenza A and B viruses circulate among humans causing epidemics almost annually. While various hosts for influenza A viruses exist, influenza B viruses have been detected only in humans and seals. However, recurrent infections of seals in Dutch coastal waters with influenza B viruses that are antigenetically distinct from influenza B viruses circulating among humans suggest that influenza B viruses have been introduced into this seal population by another, non-human, host. Harbour porpoises (Phocoena phocoena) are sympatric with seals in these waters and are also occasionally in close contact with humans after stranding and subsequent rehabilitation. In addition, virus attachment studies demonstrated that influenza B viruses can bind to cells of the respiratory tract of these animals. Therefore, we hypothesized that harbour porpoises might be a reservoir of influenza B viruses. In the present study, an unique set of serum samples from 79 harbour porpoises, stranded alive on the Dutch coast between 2003 and 2013, was tested for the presence of antibodies against influenza B viruses by use of the hemagglutination inhibition test and for antibodies against influenza A viruses by use of a competitive influenza A nucleoprotein ELISA. No antibodies were detected against either virus, suggesting that influenza A and B virus infections of harbour porpoises in Dutch coastal waters are not common, which was supported by statistical analysis of the dataset. Article in Journal/Newspaper Phocoena phocoena Erasmus University Rotterdam & Erasmus MC Research Portal PLoS ONE 9 2 e89058
institution Open Polar
collection Erasmus University Rotterdam & Erasmus MC Research Portal
op_collection_id fturottercrispub
language unknown
description Influenza A and B viruses circulate among humans causing epidemics almost annually. While various hosts for influenza A viruses exist, influenza B viruses have been detected only in humans and seals. However, recurrent infections of seals in Dutch coastal waters with influenza B viruses that are antigenetically distinct from influenza B viruses circulating among humans suggest that influenza B viruses have been introduced into this seal population by another, non-human, host. Harbour porpoises (Phocoena phocoena) are sympatric with seals in these waters and are also occasionally in close contact with humans after stranding and subsequent rehabilitation. In addition, virus attachment studies demonstrated that influenza B viruses can bind to cells of the respiratory tract of these animals. Therefore, we hypothesized that harbour porpoises might be a reservoir of influenza B viruses. In the present study, an unique set of serum samples from 79 harbour porpoises, stranded alive on the Dutch coast between 2003 and 2013, was tested for the presence of antibodies against influenza B viruses by use of the hemagglutination inhibition test and for antibodies against influenza A viruses by use of a competitive influenza A nucleoprotein ELISA. No antibodies were detected against either virus, suggesting that influenza A and B virus infections of harbour porpoises in Dutch coastal waters are not common, which was supported by statistical analysis of the dataset.
format Article in Journal/Newspaper
author Bodewes, Rogier
van de Bildt, Marco
Elk, Niels
Bunskoek, PE
van de Vijver, David
Smits, Saskia
Osterhaus, Ab
Kuiken, Thijs
spellingShingle Bodewes, Rogier
van de Bildt, Marco
Elk, Niels
Bunskoek, PE
van de Vijver, David
Smits, Saskia
Osterhaus, Ab
Kuiken, Thijs
No Serological Evidence that Harbour Porpoises Are Additional Hosts of Influenza B Viruses
author_facet Bodewes, Rogier
van de Bildt, Marco
Elk, Niels
Bunskoek, PE
van de Vijver, David
Smits, Saskia
Osterhaus, Ab
Kuiken, Thijs
author_sort Bodewes, Rogier
title No Serological Evidence that Harbour Porpoises Are Additional Hosts of Influenza B Viruses
title_short No Serological Evidence that Harbour Porpoises Are Additional Hosts of Influenza B Viruses
title_full No Serological Evidence that Harbour Porpoises Are Additional Hosts of Influenza B Viruses
title_fullStr No Serological Evidence that Harbour Porpoises Are Additional Hosts of Influenza B Viruses
title_full_unstemmed No Serological Evidence that Harbour Porpoises Are Additional Hosts of Influenza B Viruses
title_sort no serological evidence that harbour porpoises are additional hosts of influenza b viruses
publishDate 2014
url https://pure.eur.nl/en/publications/fd68ffc7-2c56-4c58-8980-b51612f9aff6
https://doi.org/10.1371/journal.pone.0089058
https://pure.eur.nl/ws/files/47591354/journal.pone.0089058.pdf
genre Phocoena phocoena
genre_facet Phocoena phocoena
op_source Bodewes , R , van de Bildt , M , Elk , N , Bunskoek , PE , van de Vijver , D , Smits , S , Osterhaus , A & Kuiken , T 2014 , ' No Serological Evidence that Harbour Porpoises Are Additional Hosts of Influenza B Viruses ' , PLoS One (print) , vol. 9 , no. 2 . https://doi.org/10.1371/journal.pone.0089058
op_rights info:eu-repo/semantics/openAccess
op_doi https://doi.org/10.1371/journal.pone.0089058
container_title PLoS ONE
container_volume 9
container_issue 2
container_start_page e89058
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