Asthma and Respiratory Symptoms in Nordic Countries, Environmental and Personal Risk Factors
The overall aims of our studies were to identify risk factors for respiratory symptoms and asthma in indoor environment but even to look at some personal risk factors such as body mass index and gastroesophageal reflux. The study population is based on participants of the European Community Respirat...
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Uppsala universitet, Institutionen för medicinska vetenskaper
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ftuppsalauniv:oai:DiVA.org:uu-7076 2023-05-15T16:52:48+02:00 Asthma and Respiratory Symptoms in Nordic Countries, Environmental and Personal Risk Factors Gunnbjörnsdóttir, María Ingibjörg 2006 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7076 eng eng Uppsala universitet, Institutionen för medicinska vetenskaper Uppsala : Acta Universitatis Upsaliensis Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, 1651-6206 159 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7076 urn:isbn:91-554-6614-1 info:eu-repo/semantics/openAccess Medicine epidemiology asthma respiratory symptoms prevalence incidence indoor dampness body mass index gastroesophageal reflux snoring indoor allergens house dust mites moulds bacteria Medicin Doctoral thesis, comprehensive summary info:eu-repo/semantics/doctoralThesis text 2006 ftuppsalauniv 2023-02-23T21:44:21Z The overall aims of our studies were to identify risk factors for respiratory symptoms and asthma in indoor environment but even to look at some personal risk factors such as body mass index and gastroesophageal reflux. The study population is based on participants of the European Community Respiratory Health Survey I and II. In the first study, water damage and visible moulds were reported in 7.4% and 17% of the homes respectively. The combination of water damage and visible moulds was independently associated with attacks of breathlessness when resting and after activity and also to long term cough. In the second study, the prevalence of nocturnal GER increased with higher BMI and the same pattern could be seen for habitual snoring. Reported onset of asthma, wheeze and night-time symptoms increased in prevalence along with the BMI gradient. In the multivariable analysis, obesity and nocturnal GER were independent risk factors for onset of asthma, wheeze and night-time symptoms. Habitual snoring was an independent risk factor for onset of wheeze and night-time symptoms, but not for onset of asthma. In the third study, a total of 18% of the subjects reported indoor dampness in the last 12 months and 27% of the subjects reported indoor dampness since the previous survey. Respiratory symptoms and asthma were significantly more prevalent in individuals exposed to indoor dampness and indoor dampness was a risk factor for respiratory symptoms and asthma after adjusting for possible confounders. Indoor dampness was an independent risk factor for onset of respiratory symptoms but not for asthma onset. Remission of respiratory symptoms was less likely to occur if subjects reported indoor dampness. In the fourth study, the lowest prevalence of atopy and the lowest levels of all indoor allergens, bacteria and moulds were found in Iceland. A positive association was found, between cat allergen exposure and asthma symptoms and between bronchial hyperresponsiveness and the amount of viable mould in indoor air. Doctoral or Postdoctoral Thesis Iceland Uppsala University: Publications (DiVA) |
institution |
Open Polar |
collection |
Uppsala University: Publications (DiVA) |
op_collection_id |
ftuppsalauniv |
language |
English |
topic |
Medicine epidemiology asthma respiratory symptoms prevalence incidence indoor dampness body mass index gastroesophageal reflux snoring indoor allergens house dust mites moulds bacteria Medicin |
spellingShingle |
Medicine epidemiology asthma respiratory symptoms prevalence incidence indoor dampness body mass index gastroesophageal reflux snoring indoor allergens house dust mites moulds bacteria Medicin Gunnbjörnsdóttir, María Ingibjörg Asthma and Respiratory Symptoms in Nordic Countries, Environmental and Personal Risk Factors |
topic_facet |
Medicine epidemiology asthma respiratory symptoms prevalence incidence indoor dampness body mass index gastroesophageal reflux snoring indoor allergens house dust mites moulds bacteria Medicin |
description |
The overall aims of our studies were to identify risk factors for respiratory symptoms and asthma in indoor environment but even to look at some personal risk factors such as body mass index and gastroesophageal reflux. The study population is based on participants of the European Community Respiratory Health Survey I and II. In the first study, water damage and visible moulds were reported in 7.4% and 17% of the homes respectively. The combination of water damage and visible moulds was independently associated with attacks of breathlessness when resting and after activity and also to long term cough. In the second study, the prevalence of nocturnal GER increased with higher BMI and the same pattern could be seen for habitual snoring. Reported onset of asthma, wheeze and night-time symptoms increased in prevalence along with the BMI gradient. In the multivariable analysis, obesity and nocturnal GER were independent risk factors for onset of asthma, wheeze and night-time symptoms. Habitual snoring was an independent risk factor for onset of wheeze and night-time symptoms, but not for onset of asthma. In the third study, a total of 18% of the subjects reported indoor dampness in the last 12 months and 27% of the subjects reported indoor dampness since the previous survey. Respiratory symptoms and asthma were significantly more prevalent in individuals exposed to indoor dampness and indoor dampness was a risk factor for respiratory symptoms and asthma after adjusting for possible confounders. Indoor dampness was an independent risk factor for onset of respiratory symptoms but not for asthma onset. Remission of respiratory symptoms was less likely to occur if subjects reported indoor dampness. In the fourth study, the lowest prevalence of atopy and the lowest levels of all indoor allergens, bacteria and moulds were found in Iceland. A positive association was found, between cat allergen exposure and asthma symptoms and between bronchial hyperresponsiveness and the amount of viable mould in indoor air. |
format |
Doctoral or Postdoctoral Thesis |
author |
Gunnbjörnsdóttir, María Ingibjörg |
author_facet |
Gunnbjörnsdóttir, María Ingibjörg |
author_sort |
Gunnbjörnsdóttir, María Ingibjörg |
title |
Asthma and Respiratory Symptoms in Nordic Countries, Environmental and Personal Risk Factors |
title_short |
Asthma and Respiratory Symptoms in Nordic Countries, Environmental and Personal Risk Factors |
title_full |
Asthma and Respiratory Symptoms in Nordic Countries, Environmental and Personal Risk Factors |
title_fullStr |
Asthma and Respiratory Symptoms in Nordic Countries, Environmental and Personal Risk Factors |
title_full_unstemmed |
Asthma and Respiratory Symptoms in Nordic Countries, Environmental and Personal Risk Factors |
title_sort |
asthma and respiratory symptoms in nordic countries, environmental and personal risk factors |
publisher |
Uppsala universitet, Institutionen för medicinska vetenskaper |
publishDate |
2006 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7076 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, 1651-6206 159 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7076 urn:isbn:91-554-6614-1 |
op_rights |
info:eu-repo/semantics/openAccess |
_version_ |
1766043222086254592 |