Clinical Remission of Asthma and Allergic Rhinitis- in a Longitudinal Population Study
Background: Although asthma and allergic rhinitis are chronic diseases, some patients experience periods of remission. Information on prognostic factors associated with the remission of asthma and allergic rhinitis is valuable in resource prioritization. This study investigated factors associated wi...
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Uppsala universitet, Lung- allergi- och sömnforskning
2022
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-489343 https://doi.org/10.2147/JAA.S378584 |
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ftuppsalauniv:oai:DiVA.org:uu-489343 2023-05-15T16:52:33+02:00 Clinical Remission of Asthma and Allergic Rhinitis- in a Longitudinal Population Study Heldin, Johanna Malinovschi, Andrei Johannessen, Ane Alving, Kjell Holm, Mathias Franklin, Karl A. Forsberg, Bertil Schlunssen, Vivi Jõgi, Rain Gislason, Thorarinn Benediktsdottir, Bryndis Svanes, Cecilie Janson, Christer 2022 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-489343 https://doi.org/10.2147/JAA.S378584 eng eng Uppsala universitet, Lung- allergi- och sömnforskning Uppsala universitet, Klinisk fysiologi Uppsala universitet, Pediatrisk inflammations- och metabolismforskning samt barnhälsa Univ Bergen, Ctr Int Hlth, Dept Global Publ Hlth & Primary Care, Bergen, Norway. Univ Gothenburg, Sch Publ Hlth & Community Med, Inst Med, Occupat & Environm Med, Gothenburg, Sweden. Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden. Umeå Univ, Dept Publ Hlth & Clin Med, Sect Sustainable Hlth, Umeå, Sweden. Aarhus Univ, Danish Ramazzini Ctr, Unit Environm Occupat & Hlth, Dept Publ Hlth, Aarhus, Denmark.;Natl Res Ctr Working Environm, Copenhagen, Denmark. Tartu Univ Hosp, Lung Clin, Tartu, Estonia. Univ Iceland, Med Fac, Reykjavik, Iceland.;Landspitali Univ Hosp Reykjavik, Dept Sleep, Reykjavik, Iceland. Univ Bergen, Ctr Int Hlth, Dept Global Publ Hlth & Primary Care, Bergen, Norway.;Haukeland Hosp, Dept Occupat Med, Bergen, Norway. Informa UK Limited Journal of Asthma and Allergy, 1178-6965, 2022, 15, s. 1569-1578 orcid:0000-0002-4098-7765 orcid:0000-0003-0784-0443 orcid:0000-0003-0869-6914 orcid:0000-0001-5093-6980 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-489343 doi:10.2147/JAA.S378584 PMID 36387839 ISI:000882371400001 info:eu-repo/semantics/openAccess asthma allergic rhinitis remission epidemiology Respiratory Medicine and Allergy Lungmedicin och allergi Article in journal info:eu-repo/semantics/article text 2022 ftuppsalauniv https://doi.org/10.2147/JAA.S378584 2023-02-23T22:01:24Z Background: Although asthma and allergic rhinitis are chronic diseases, some patients experience periods of remission. Information on prognostic factors associated with the remission of asthma and allergic rhinitis is valuable in resource prioritization. This study investigated factors associated with the clinical remission of asthma and allergic rhinitis.Methods: In the Respiratory Health In Northern Europe (RHINE) study, data was collected with questionnaires in stage one (RHINE I, 1989-1992) and two follow-ups (RHINE II, 1999-2001 and RHINE III, 2010-2012) from Sweden, Norway, Denmark, Iceland and Estonia. Clinical remission was defined as having reported asthma or allergic rhinitis in RHINE I or RHINE II but not in RHINE III.Results: Of 13,052 participants, 975 (7.5%) reported asthma in RHINE I or RHINE II, and 3379 (25.9%) allergic rhinitis. Clinical remission of asthma and allergic rhinitis was found in 46.4% and 31.8%, respectively. Living in Estonia (OR (95% CI) 2.44 (1.22- 4.85)) and living in an apartment (1.45 (1.06-1.98)) were related to remission of asthma, while subjects reporting allergic rhinitis (0.68 (0.51-0.90)), asthma onset <= 12 years of age (0.49 (0.35-0.68)), receiving treatment with antibiotics for respiratory illness (0.64 (0.47- 0.87)) were less likely to have asthma remission. Factors related to a higher likelihood of remission of allergic rhinitis were no asthma at baseline, age >= 58 years in RHINE III, allergic rhinitis onset after 12 years of age, living in rural areas as a child, having only a primary school education and not being pregnant.Conclusion: Clinical remission was found in almost one-half of those with asthma and one-third of persons with allergic rhinitis. Coexisting allergic symptoms were associated with less clinical asthma remission. Age, asthma symptoms and environmental factors in childhood, such as living in a rural area, were found to influence the clinical remission of allergic rhinitis. Article in Journal/Newspaper Iceland Uppsala University: Publications (DiVA) Norway Journal of Asthma and Allergy Volume 15 1569 1578 |
institution |
Open Polar |
collection |
Uppsala University: Publications (DiVA) |
op_collection_id |
ftuppsalauniv |
language |
English |
topic |
asthma allergic rhinitis remission epidemiology Respiratory Medicine and Allergy Lungmedicin och allergi |
spellingShingle |
asthma allergic rhinitis remission epidemiology Respiratory Medicine and Allergy Lungmedicin och allergi Heldin, Johanna Malinovschi, Andrei Johannessen, Ane Alving, Kjell Holm, Mathias Franklin, Karl A. Forsberg, Bertil Schlunssen, Vivi Jõgi, Rain Gislason, Thorarinn Benediktsdottir, Bryndis Svanes, Cecilie Janson, Christer Clinical Remission of Asthma and Allergic Rhinitis- in a Longitudinal Population Study |
topic_facet |
asthma allergic rhinitis remission epidemiology Respiratory Medicine and Allergy Lungmedicin och allergi |
description |
Background: Although asthma and allergic rhinitis are chronic diseases, some patients experience periods of remission. Information on prognostic factors associated with the remission of asthma and allergic rhinitis is valuable in resource prioritization. This study investigated factors associated with the clinical remission of asthma and allergic rhinitis.Methods: In the Respiratory Health In Northern Europe (RHINE) study, data was collected with questionnaires in stage one (RHINE I, 1989-1992) and two follow-ups (RHINE II, 1999-2001 and RHINE III, 2010-2012) from Sweden, Norway, Denmark, Iceland and Estonia. Clinical remission was defined as having reported asthma or allergic rhinitis in RHINE I or RHINE II but not in RHINE III.Results: Of 13,052 participants, 975 (7.5%) reported asthma in RHINE I or RHINE II, and 3379 (25.9%) allergic rhinitis. Clinical remission of asthma and allergic rhinitis was found in 46.4% and 31.8%, respectively. Living in Estonia (OR (95% CI) 2.44 (1.22- 4.85)) and living in an apartment (1.45 (1.06-1.98)) were related to remission of asthma, while subjects reporting allergic rhinitis (0.68 (0.51-0.90)), asthma onset <= 12 years of age (0.49 (0.35-0.68)), receiving treatment with antibiotics for respiratory illness (0.64 (0.47- 0.87)) were less likely to have asthma remission. Factors related to a higher likelihood of remission of allergic rhinitis were no asthma at baseline, age >= 58 years in RHINE III, allergic rhinitis onset after 12 years of age, living in rural areas as a child, having only a primary school education and not being pregnant.Conclusion: Clinical remission was found in almost one-half of those with asthma and one-third of persons with allergic rhinitis. Coexisting allergic symptoms were associated with less clinical asthma remission. Age, asthma symptoms and environmental factors in childhood, such as living in a rural area, were found to influence the clinical remission of allergic rhinitis. |
format |
Article in Journal/Newspaper |
author |
Heldin, Johanna Malinovschi, Andrei Johannessen, Ane Alving, Kjell Holm, Mathias Franklin, Karl A. Forsberg, Bertil Schlunssen, Vivi Jõgi, Rain Gislason, Thorarinn Benediktsdottir, Bryndis Svanes, Cecilie Janson, Christer |
author_facet |
Heldin, Johanna Malinovschi, Andrei Johannessen, Ane Alving, Kjell Holm, Mathias Franklin, Karl A. Forsberg, Bertil Schlunssen, Vivi Jõgi, Rain Gislason, Thorarinn Benediktsdottir, Bryndis Svanes, Cecilie Janson, Christer |
author_sort |
Heldin, Johanna |
title |
Clinical Remission of Asthma and Allergic Rhinitis- in a Longitudinal Population Study |
title_short |
Clinical Remission of Asthma and Allergic Rhinitis- in a Longitudinal Population Study |
title_full |
Clinical Remission of Asthma and Allergic Rhinitis- in a Longitudinal Population Study |
title_fullStr |
Clinical Remission of Asthma and Allergic Rhinitis- in a Longitudinal Population Study |
title_full_unstemmed |
Clinical Remission of Asthma and Allergic Rhinitis- in a Longitudinal Population Study |
title_sort |
clinical remission of asthma and allergic rhinitis- in a longitudinal population study |
publisher |
Uppsala universitet, Lung- allergi- och sömnforskning |
publishDate |
2022 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-489343 https://doi.org/10.2147/JAA.S378584 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
Journal of Asthma and Allergy, 1178-6965, 2022, 15, s. 1569-1578 orcid:0000-0002-4098-7765 orcid:0000-0003-0784-0443 orcid:0000-0003-0869-6914 orcid:0000-0001-5093-6980 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-489343 doi:10.2147/JAA.S378584 PMID 36387839 ISI:000882371400001 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.2147/JAA.S378584 |
container_title |
Journal of Asthma and Allergy |
container_volume |
Volume 15 |
container_start_page |
1569 |
op_container_end_page |
1578 |
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1766042893154254848 |