Lifetime exposure to violence and other life stressors and hair cortisol concentration in women
Women are exposed to a variety of life stressors, particularly violence, during their lifetime which increases the risk of developing various psychiatric and somatic diseases, with the dysregulated secretion of cortisol as one potential biological mechanism. We examined the association between viole...
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Uppsala universitet, Kunskapscentrum för katastrofpsykiatri
2022
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-474551 https://doi.org/10.1080/10253890.2021.2011204 |
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ftuppsalauniv:oai:DiVA.org:uu-474551 2023-05-15T16:51:50+02:00 Lifetime exposure to violence and other life stressors and hair cortisol concentration in women Lynch, Rebekka Aspelund, Thor Kormáksson, Matthías Flores-Torres, Mario H Hauksdóttir, Arna Arnberg, Filip Lajous, Martín Kirschbaum, Clemens Valdimarsdóttir, Unnur 2022 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-474551 https://doi.org/10.1080/10253890.2021.2011204 eng eng Uppsala universitet, Kunskapscentrum för katastrofpsykiatri Uppsala universitet, Institutionen för neurovetenskap Stress, 1025-3890, 2022, 25:1, s. 48-56 orcid:0000-0002-1317-2093 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-474551 doi:10.1080/10253890.2021.2011204 PMID 34962229 ISI:000740923800001 info:eu-repo/semantics/openAccess Violence cortisol gender hair cortisol life stressor violence against women Psychology Psykologi Article in journal info:eu-repo/semantics/article text 2022 ftuppsalauniv https://doi.org/10.1080/10253890.2021.2011204 2023-02-23T22:00:42Z Women are exposed to a variety of life stressors, particularly violence, during their lifetime which increases the risk of developing various psychiatric and somatic diseases, with the dysregulated secretion of cortisol as one potential biological mechanism. We examined the association between violence and other life stressors and hair cortisol concentration (HCC) in a population of urban women. We included 470 adult women (age = 21-86 years) attending the Cancer Detection Clinic in Iceland. The Life Stressor Checklist-Revised (LSC-R; 30-items) was used to assess exposure. HCC was measured with liquid chromatography coupled with tandem mass spectrometry. We used linear regression models to assess the association between life stressors and log-transformed HCC. The median HCC (pg/mg) in the study population was 4.9 (range 0.6-616.6). HCC was not associated with background covariates, including age (p = 0.868), education level (p = 0.824), marital status (p = 0.545), income (p = 0.363), occupation (p = 0.192), but associated with current smoking (p = 0.013). We noted a 3.3% (95% CI: 0.17-6.6%) associated increase in HCC per endorsed life stressor after adjusting for age and smoking, while non-violent life stressors were not associated with HCC. Per endorsed violence item, we observed a 10.2% (95% CI: 1.4-19.7%) associated increase in HCC after age and smoking adjustment. Women with lifetime exposure to both physical and sexual violence presented with higher HCC than unexposed women (p = 0.010), after age and smoking adjustment. Lifetime exposure to violence was associated with higher levels of HCC in a community sample of women. These findings need confirmation with prospective studies. Article in Journal/Newspaper Iceland Uppsala University: Publications (DiVA) Stress 25 1 48 56 |
institution |
Open Polar |
collection |
Uppsala University: Publications (DiVA) |
op_collection_id |
ftuppsalauniv |
language |
English |
topic |
Violence cortisol gender hair cortisol life stressor violence against women Psychology Psykologi |
spellingShingle |
Violence cortisol gender hair cortisol life stressor violence against women Psychology Psykologi Lynch, Rebekka Aspelund, Thor Kormáksson, Matthías Flores-Torres, Mario H Hauksdóttir, Arna Arnberg, Filip Lajous, Martín Kirschbaum, Clemens Valdimarsdóttir, Unnur Lifetime exposure to violence and other life stressors and hair cortisol concentration in women |
topic_facet |
Violence cortisol gender hair cortisol life stressor violence against women Psychology Psykologi |
description |
Women are exposed to a variety of life stressors, particularly violence, during their lifetime which increases the risk of developing various psychiatric and somatic diseases, with the dysregulated secretion of cortisol as one potential biological mechanism. We examined the association between violence and other life stressors and hair cortisol concentration (HCC) in a population of urban women. We included 470 adult women (age = 21-86 years) attending the Cancer Detection Clinic in Iceland. The Life Stressor Checklist-Revised (LSC-R; 30-items) was used to assess exposure. HCC was measured with liquid chromatography coupled with tandem mass spectrometry. We used linear regression models to assess the association between life stressors and log-transformed HCC. The median HCC (pg/mg) in the study population was 4.9 (range 0.6-616.6). HCC was not associated with background covariates, including age (p = 0.868), education level (p = 0.824), marital status (p = 0.545), income (p = 0.363), occupation (p = 0.192), but associated with current smoking (p = 0.013). We noted a 3.3% (95% CI: 0.17-6.6%) associated increase in HCC per endorsed life stressor after adjusting for age and smoking, while non-violent life stressors were not associated with HCC. Per endorsed violence item, we observed a 10.2% (95% CI: 1.4-19.7%) associated increase in HCC after age and smoking adjustment. Women with lifetime exposure to both physical and sexual violence presented with higher HCC than unexposed women (p = 0.010), after age and smoking adjustment. Lifetime exposure to violence was associated with higher levels of HCC in a community sample of women. These findings need confirmation with prospective studies. |
format |
Article in Journal/Newspaper |
author |
Lynch, Rebekka Aspelund, Thor Kormáksson, Matthías Flores-Torres, Mario H Hauksdóttir, Arna Arnberg, Filip Lajous, Martín Kirschbaum, Clemens Valdimarsdóttir, Unnur |
author_facet |
Lynch, Rebekka Aspelund, Thor Kormáksson, Matthías Flores-Torres, Mario H Hauksdóttir, Arna Arnberg, Filip Lajous, Martín Kirschbaum, Clemens Valdimarsdóttir, Unnur |
author_sort |
Lynch, Rebekka |
title |
Lifetime exposure to violence and other life stressors and hair cortisol concentration in women |
title_short |
Lifetime exposure to violence and other life stressors and hair cortisol concentration in women |
title_full |
Lifetime exposure to violence and other life stressors and hair cortisol concentration in women |
title_fullStr |
Lifetime exposure to violence and other life stressors and hair cortisol concentration in women |
title_full_unstemmed |
Lifetime exposure to violence and other life stressors and hair cortisol concentration in women |
title_sort |
lifetime exposure to violence and other life stressors and hair cortisol concentration in women |
publisher |
Uppsala universitet, Kunskapscentrum för katastrofpsykiatri |
publishDate |
2022 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-474551 https://doi.org/10.1080/10253890.2021.2011204 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
Stress, 1025-3890, 2022, 25:1, s. 48-56 orcid:0000-0002-1317-2093 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-474551 doi:10.1080/10253890.2021.2011204 PMID 34962229 ISI:000740923800001 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1080/10253890.2021.2011204 |
container_title |
Stress |
container_volume |
25 |
container_issue |
1 |
container_start_page |
48 |
op_container_end_page |
56 |
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1766041945206947840 |