Positive selection plays a major role in shaping signatures of differentiation across the genomic landscape of two independent Ficedula flycatcher species pairs
A current debate within population genomics surrounds the relevance of patterns of genomic differentiation between closely related species for our understanding of adaptation and speciation. Mounting evidence across many taxa suggests that the same genomic regions repeatedly develop elevated differe...
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Uppsala universitet, Evolutionsbiologi
2021
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-468157 https://doi.org/10.1111/evo.14234 |
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ftuppsalauniv:oai:DiVA.org:uu-468157 2024-02-11T10:09:04+01:00 Positive selection plays a major role in shaping signatures of differentiation across the genomic landscape of two independent Ficedula flycatcher species pairs Chase, Madeline A. Ellegren, Hans Mugal, Carina F. 2021 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-468157 https://doi.org/10.1111/evo.14234 eng eng Uppsala universitet, Evolutionsbiologi Wiley Evolution, 0014-3820, 2021, 75:9, s. 2179-2196 orcid:0000-0002-7916-3560 orcid:0000-0002-5035-1736 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-468157 doi:10.1111/evo.14234 PMID 33851440 ISI:000646158400001 info:eu-repo/semantics/openAccess Linked selection recombination rate selective sweep speciation genomics Evolutionary Biology Evolutionsbiologi Genetics Genetik Article in journal info:eu-repo/semantics/article text 2021 ftuppsalauniv https://doi.org/10.1111/evo.14234 2024-01-17T23:32:49Z A current debate within population genomics surrounds the relevance of patterns of genomic differentiation between closely related species for our understanding of adaptation and speciation. Mounting evidence across many taxa suggests that the same genomic regions repeatedly develop elevated differentiation in independent species pairs. These regions often coincide with high gene density and/or low recombination, leading to the hypothesis that the genomic differentiation landscape mostly reflects a history of background selection, and reveals little about adaptation or speciation. A comparative genomics approach with multiple independent species pairs at a timescale where gene flow and ILS are negligible permits investigating whether different evolutionary processes are responsible for generating lineage-specific versus shared patterns of species differentiation. We use whole-genome resequencing data of 195 individuals from four Ficedula flycatcher species comprising two independent species pairs: collared and pied flycatchers, and red-breasted and taiga flycatchers. We found that both shared and lineage-specific FST peaks could partially be explained by selective sweeps, with recurrent selection likely to underlie shared signatures of selection, whereas indirect evidence supports a role of recombination landscape evolution in driving lineage-specific signatures of selection. This work therefore provides evidence for an interplay of positive selection and recombination to genomic landscape evolution. Article in Journal/Newspaper taiga Uppsala University: Publications (DiVA) Evolution 75 9 2179 2196 |
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Open Polar |
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Uppsala University: Publications (DiVA) |
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ftuppsalauniv |
language |
English |
topic |
Linked selection recombination rate selective sweep speciation genomics Evolutionary Biology Evolutionsbiologi Genetics Genetik |
spellingShingle |
Linked selection recombination rate selective sweep speciation genomics Evolutionary Biology Evolutionsbiologi Genetics Genetik Chase, Madeline A. Ellegren, Hans Mugal, Carina F. Positive selection plays a major role in shaping signatures of differentiation across the genomic landscape of two independent Ficedula flycatcher species pairs |
topic_facet |
Linked selection recombination rate selective sweep speciation genomics Evolutionary Biology Evolutionsbiologi Genetics Genetik |
description |
A current debate within population genomics surrounds the relevance of patterns of genomic differentiation between closely related species for our understanding of adaptation and speciation. Mounting evidence across many taxa suggests that the same genomic regions repeatedly develop elevated differentiation in independent species pairs. These regions often coincide with high gene density and/or low recombination, leading to the hypothesis that the genomic differentiation landscape mostly reflects a history of background selection, and reveals little about adaptation or speciation. A comparative genomics approach with multiple independent species pairs at a timescale where gene flow and ILS are negligible permits investigating whether different evolutionary processes are responsible for generating lineage-specific versus shared patterns of species differentiation. We use whole-genome resequencing data of 195 individuals from four Ficedula flycatcher species comprising two independent species pairs: collared and pied flycatchers, and red-breasted and taiga flycatchers. We found that both shared and lineage-specific FST peaks could partially be explained by selective sweeps, with recurrent selection likely to underlie shared signatures of selection, whereas indirect evidence supports a role of recombination landscape evolution in driving lineage-specific signatures of selection. This work therefore provides evidence for an interplay of positive selection and recombination to genomic landscape evolution. |
format |
Article in Journal/Newspaper |
author |
Chase, Madeline A. Ellegren, Hans Mugal, Carina F. |
author_facet |
Chase, Madeline A. Ellegren, Hans Mugal, Carina F. |
author_sort |
Chase, Madeline A. |
title |
Positive selection plays a major role in shaping signatures of differentiation across the genomic landscape of two independent Ficedula flycatcher species pairs |
title_short |
Positive selection plays a major role in shaping signatures of differentiation across the genomic landscape of two independent Ficedula flycatcher species pairs |
title_full |
Positive selection plays a major role in shaping signatures of differentiation across the genomic landscape of two independent Ficedula flycatcher species pairs |
title_fullStr |
Positive selection plays a major role in shaping signatures of differentiation across the genomic landscape of two independent Ficedula flycatcher species pairs |
title_full_unstemmed |
Positive selection plays a major role in shaping signatures of differentiation across the genomic landscape of two independent Ficedula flycatcher species pairs |
title_sort |
positive selection plays a major role in shaping signatures of differentiation across the genomic landscape of two independent ficedula flycatcher species pairs |
publisher |
Uppsala universitet, Evolutionsbiologi |
publishDate |
2021 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-468157 https://doi.org/10.1111/evo.14234 |
genre |
taiga |
genre_facet |
taiga |
op_relation |
Evolution, 0014-3820, 2021, 75:9, s. 2179-2196 orcid:0000-0002-7916-3560 orcid:0000-0002-5035-1736 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-468157 doi:10.1111/evo.14234 PMID 33851440 ISI:000646158400001 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1111/evo.14234 |
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Evolution |
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75 |
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9 |
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2179 |
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2196 |
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1790608789511077888 |