Evidence for the Introduction, Reassortment, and Persistence of Diverse Influenza A Viruses in Antarctica
Avian influenza virus (AIV) surveillance in Antarctica during 2013 revealed the prevalence of evolutionarily distinct influenza viruses of the H11N2 subtype in Adelie penguins. Here we present results from the continued surveillance of AIV on the Antarctic Peninsula during 2014 and 2015. In addition...
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Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi
2016
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-307521 https://doi.org/10.1128/JVI.01404-16 |
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ftuppsalauniv:oai:DiVA.org:uu-307521 2023-05-15T14:02:17+02:00 Evidence for the Introduction, Reassortment, and Persistence of Diverse Influenza A Viruses in Antarctica Hurt, Aeron C. Su, Yvonne C. F. Aban, Malet Peck, Heidi Lau, Hilda Baas, Chantal Deng, Yi-Mo Spirason, Natalie Ellström, Patrik Hernandez, Jorge Olsen, Björn Barr, Ian G. Vijaykrishna, Dhanasekaran Gonzalez-Acuna, Daniel 2016 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-307521 https://doi.org/10.1128/JVI.01404-16 eng eng Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi Uppsala universitet, Infektionsmedicin WHO, Collaborating Ctr Reference & Res Influenza, Parkville, Vic, Australia.;Univ Melbourne, Melbourne Sch Populat & Global Hlth, Parkville, Vic, Australia. Duke NUS Med Sch, Program Emerging Infect Dis, Singapore, Singapore. WHO, Collaborating Ctr Reference & Res Influenza, Parkville, Vic, Australia. Kalmar Cty Hosp, Dept Microbiol, Kalmar, Sweden. Univ Concepcion, Fac Ciencias Vet, Chillan, Chile. Journal of Virology, 0022-538X, 2016, 90:21, s. 9674-9682 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-307521 doi:10.1128/JVI.01404-16 PMID 27535050 ISI:000385525700011 info:eu-repo/semantics/openAccess Infectious Medicine Infektionsmedicin Article in journal info:eu-repo/semantics/article text 2016 ftuppsalauniv https://doi.org/10.1128/JVI.01404-16 2023-02-23T22:00:58Z Avian influenza virus (AIV) surveillance in Antarctica during 2013 revealed the prevalence of evolutionarily distinct influenza viruses of the H11N2 subtype in Adelie penguins. Here we present results from the continued surveillance of AIV on the Antarctic Peninsula during 2014 and 2015. In addition to the continued detection of H11 subtype viruses in a snowy sheathbill during 2014, we isolated a novel H5N5 subtype virus from a chinstrap penguin during 2015. Gene sequencing and phylogenetic analysis revealed that the H11 virus detected in 2014 had a >99.1% nucleotide similarity to the H11N2 viruses isolated in 2013, suggesting the continued prevalence of this virus in Antarctica over multiple years. However, phylogenetic analysis of the H5N5 virus showed that the genome segments were recently introduced to the continent, except for the NP gene, which was similar to that in the endemic H11N2 viruses. Our analysis indicates geographically diverse origins for the H5N5 virus genes, with the majority of its genome segments derived from North American lineage viruses but the neuraminidase gene derived from a Eurasian lineage virus. In summary, we show the persistence of AIV lineages in Antarctica over multiple years, the recent introduction of gene segments from diverse regions, and reassortment between different AIV lineages in Antarctica, which together significantly increase our understanding of AIV ecology in this fragile and pristine environment. Article in Journal/Newspaper Antarc* Antarctic Antarctic Peninsula Antarctica Chinstrap penguin Snowy Sheathbill Uppsala University: Publications (DiVA) Antarctic Antarctic Peninsula The Antarctic Journal of Virology 90 21 9674 9682 |
institution |
Open Polar |
collection |
Uppsala University: Publications (DiVA) |
op_collection_id |
ftuppsalauniv |
language |
English |
topic |
Infectious Medicine Infektionsmedicin |
spellingShingle |
Infectious Medicine Infektionsmedicin Hurt, Aeron C. Su, Yvonne C. F. Aban, Malet Peck, Heidi Lau, Hilda Baas, Chantal Deng, Yi-Mo Spirason, Natalie Ellström, Patrik Hernandez, Jorge Olsen, Björn Barr, Ian G. Vijaykrishna, Dhanasekaran Gonzalez-Acuna, Daniel Evidence for the Introduction, Reassortment, and Persistence of Diverse Influenza A Viruses in Antarctica |
topic_facet |
Infectious Medicine Infektionsmedicin |
description |
Avian influenza virus (AIV) surveillance in Antarctica during 2013 revealed the prevalence of evolutionarily distinct influenza viruses of the H11N2 subtype in Adelie penguins. Here we present results from the continued surveillance of AIV on the Antarctic Peninsula during 2014 and 2015. In addition to the continued detection of H11 subtype viruses in a snowy sheathbill during 2014, we isolated a novel H5N5 subtype virus from a chinstrap penguin during 2015. Gene sequencing and phylogenetic analysis revealed that the H11 virus detected in 2014 had a >99.1% nucleotide similarity to the H11N2 viruses isolated in 2013, suggesting the continued prevalence of this virus in Antarctica over multiple years. However, phylogenetic analysis of the H5N5 virus showed that the genome segments were recently introduced to the continent, except for the NP gene, which was similar to that in the endemic H11N2 viruses. Our analysis indicates geographically diverse origins for the H5N5 virus genes, with the majority of its genome segments derived from North American lineage viruses but the neuraminidase gene derived from a Eurasian lineage virus. In summary, we show the persistence of AIV lineages in Antarctica over multiple years, the recent introduction of gene segments from diverse regions, and reassortment between different AIV lineages in Antarctica, which together significantly increase our understanding of AIV ecology in this fragile and pristine environment. |
format |
Article in Journal/Newspaper |
author |
Hurt, Aeron C. Su, Yvonne C. F. Aban, Malet Peck, Heidi Lau, Hilda Baas, Chantal Deng, Yi-Mo Spirason, Natalie Ellström, Patrik Hernandez, Jorge Olsen, Björn Barr, Ian G. Vijaykrishna, Dhanasekaran Gonzalez-Acuna, Daniel |
author_facet |
Hurt, Aeron C. Su, Yvonne C. F. Aban, Malet Peck, Heidi Lau, Hilda Baas, Chantal Deng, Yi-Mo Spirason, Natalie Ellström, Patrik Hernandez, Jorge Olsen, Björn Barr, Ian G. Vijaykrishna, Dhanasekaran Gonzalez-Acuna, Daniel |
author_sort |
Hurt, Aeron C. |
title |
Evidence for the Introduction, Reassortment, and Persistence of Diverse Influenza A Viruses in Antarctica |
title_short |
Evidence for the Introduction, Reassortment, and Persistence of Diverse Influenza A Viruses in Antarctica |
title_full |
Evidence for the Introduction, Reassortment, and Persistence of Diverse Influenza A Viruses in Antarctica |
title_fullStr |
Evidence for the Introduction, Reassortment, and Persistence of Diverse Influenza A Viruses in Antarctica |
title_full_unstemmed |
Evidence for the Introduction, Reassortment, and Persistence of Diverse Influenza A Viruses in Antarctica |
title_sort |
evidence for the introduction, reassortment, and persistence of diverse influenza a viruses in antarctica |
publisher |
Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi |
publishDate |
2016 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-307521 https://doi.org/10.1128/JVI.01404-16 |
geographic |
Antarctic Antarctic Peninsula The Antarctic |
geographic_facet |
Antarctic Antarctic Peninsula The Antarctic |
genre |
Antarc* Antarctic Antarctic Peninsula Antarctica Chinstrap penguin Snowy Sheathbill |
genre_facet |
Antarc* Antarctic Antarctic Peninsula Antarctica Chinstrap penguin Snowy Sheathbill |
op_relation |
Journal of Virology, 0022-538X, 2016, 90:21, s. 9674-9682 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-307521 doi:10.1128/JVI.01404-16 PMID 27535050 ISI:000385525700011 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1128/JVI.01404-16 |
container_title |
Journal of Virology |
container_volume |
90 |
container_issue |
21 |
container_start_page |
9674 |
op_container_end_page |
9682 |
_version_ |
1766272439898079232 |