Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis

• Published in: Arthritis Research & Therapy
• Main Authors: Brink, Mikael, Hansson, Monika, Mathsson-Alm, Linda, Wijayatunga, Priyantha, Verheul, Marije K., Trouw, Leendert A., Holmdahl, Rikard, Rönnelid, Johan, Klareskog, Lars, Rantapaa-Dahlqvist, Solbritt
• Format: Article in Journal/Newspaper
• Language: English
• Published: Uppsala universitet, Klinisk immunologi 2016
• Subjects: Rheumatoid arthritis; Rheumatoid factor; Anti-citrullinated peptide antibodies; Pre-symptomatic individuals; Anti-carbamylated protein antibodies; Anti-CCP2 antibodies; Immunology; Immunologi; Elia; Northern Sweden
• Online Access: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-280252; https://doi.org/10.1186/s13075-016-0940-2

Background: The presence of rheumatoid factor (RF), anti-carbamylated protein antibodies (anti-CarP) and antibodies against citrullinated protein and peptides (ACPA) precedes the onset of symptoms of rheumatoid arthritis (RA) by several years. Relationships between the development of these antibodie...