Speciation genomics : A perspective from vertebrate systems
Species are vital entities in biology. Species are generally considered to be discrete entities, consisting of a group of (usually interbreeding) individuals that are similar in phenotype and genetic composition, yet differ in significant ways from other species. The study of speciation has focussed...
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Uppsala universitet, Evolutionsbiologi
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ftuppsalauniv:oai:DiVA.org:uu-265342 2023-05-15T17:03:33+02:00 Speciation genomics : A perspective from vertebrate systems Vijay, Nagarjun 2016 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-265342 eng eng Uppsala universitet, Evolutionsbiologi Uppsala Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, 1651-6214 1326 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-265342 urn:isbn:978-91-554-9425-4 info:eu-repo/semantics/openAccess evolution speciation genomics vertebrate adaptation selection linked selection crow killer whale hybrid zone transcriptomics population genetics behaviour colouration Doctoral thesis, comprehensive summary info:eu-repo/semantics/doctoralThesis text 2016 ftuppsalauniv 2023-02-23T21:39:36Z Species are vital entities in biology. Species are generally considered to be discrete entities, consisting of a group of (usually interbreeding) individuals that are similar in phenotype and genetic composition, yet differ in significant ways from other species. The study of speciation has focussed on understanding general evolutionary mechanisms involved in the accumulation of differences both at the genetic and phenotypic level. In this thesis, I investigate incipient speciation, an early stage of divergence towards evolutionary independence in closely related natural populations. I make ample use of recent advances in sequencing technology that allow 1) characterizing phenotypic divergence at the level of the transcriptome and 2) delineate patterns of genetic variation at genome-scale from which processes are inferred by using principles of population genetic theory. In the first paper, we assembled a draft genome of the hooded crow and investigated population differentiation across a famous European hybrid zone. Comparing sequence differentiation peaks between and within the colour morphs, we could identify regions of the genome that show differentiation only between colour morphs and that could be related to gene expression profiles of the melanogenesis pathway coding for colour differences. The second paper expands on the first paper in that it includes crow population samples from across the entire Palaearctic distribution spanning two additional zones of contact between colour morphs. The results suggest that regions associated with selection against gene flow between colour morphs were largely idiosyncratic to each contact zone and emerged against a background of conserved 'islands of differentiation' due to shared linked selection. The third paper focusses on five killer whale ecotypes with distinct feeding and habitat specific adaptations. Differing levels of sequence differentiation between these ecotypes places them along a speciation continuum and provides a unique temporal cross-section of the ... Doctoral or Postdoctoral Thesis Killer Whale Killer whale Uppsala University: Publications (DiVA) |
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Uppsala University: Publications (DiVA) |
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ftuppsalauniv |
language |
English |
topic |
evolution speciation genomics vertebrate adaptation selection linked selection crow killer whale hybrid zone transcriptomics population genetics behaviour colouration |
spellingShingle |
evolution speciation genomics vertebrate adaptation selection linked selection crow killer whale hybrid zone transcriptomics population genetics behaviour colouration Vijay, Nagarjun Speciation genomics : A perspective from vertebrate systems |
topic_facet |
evolution speciation genomics vertebrate adaptation selection linked selection crow killer whale hybrid zone transcriptomics population genetics behaviour colouration |
description |
Species are vital entities in biology. Species are generally considered to be discrete entities, consisting of a group of (usually interbreeding) individuals that are similar in phenotype and genetic composition, yet differ in significant ways from other species. The study of speciation has focussed on understanding general evolutionary mechanisms involved in the accumulation of differences both at the genetic and phenotypic level. In this thesis, I investigate incipient speciation, an early stage of divergence towards evolutionary independence in closely related natural populations. I make ample use of recent advances in sequencing technology that allow 1) characterizing phenotypic divergence at the level of the transcriptome and 2) delineate patterns of genetic variation at genome-scale from which processes are inferred by using principles of population genetic theory. In the first paper, we assembled a draft genome of the hooded crow and investigated population differentiation across a famous European hybrid zone. Comparing sequence differentiation peaks between and within the colour morphs, we could identify regions of the genome that show differentiation only between colour morphs and that could be related to gene expression profiles of the melanogenesis pathway coding for colour differences. The second paper expands on the first paper in that it includes crow population samples from across the entire Palaearctic distribution spanning two additional zones of contact between colour morphs. The results suggest that regions associated with selection against gene flow between colour morphs were largely idiosyncratic to each contact zone and emerged against a background of conserved 'islands of differentiation' due to shared linked selection. The third paper focusses on five killer whale ecotypes with distinct feeding and habitat specific adaptations. Differing levels of sequence differentiation between these ecotypes places them along a speciation continuum and provides a unique temporal cross-section of the ... |
format |
Doctoral or Postdoctoral Thesis |
author |
Vijay, Nagarjun |
author_facet |
Vijay, Nagarjun |
author_sort |
Vijay, Nagarjun |
title |
Speciation genomics : A perspective from vertebrate systems |
title_short |
Speciation genomics : A perspective from vertebrate systems |
title_full |
Speciation genomics : A perspective from vertebrate systems |
title_fullStr |
Speciation genomics : A perspective from vertebrate systems |
title_full_unstemmed |
Speciation genomics : A perspective from vertebrate systems |
title_sort |
speciation genomics : a perspective from vertebrate systems |
publisher |
Uppsala universitet, Evolutionsbiologi |
publishDate |
2016 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-265342 |
genre |
Killer Whale Killer whale |
genre_facet |
Killer Whale Killer whale |
op_relation |
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, 1651-6214 1326 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-265342 urn:isbn:978-91-554-9425-4 |
op_rights |
info:eu-repo/semantics/openAccess |
_version_ |
1766057448853995520 |