Penicillium nalgiovense Laxa isolated from Antarctica is a new source of the antifungal metabolite amphotericin B

• Published in: Fungal Biology and Biotechnology
• Main Authors: Svahn, Stefan, Chryssanthou, Erja, Olsen, Björn, Bohlin, Lars, Göransson, Ulf
• Format: Article in Journal/Newspaper
• Language: English
• Published: Uppsala universitet, Avdelningen för farmakognosi 2015
• Subjects: Amphotericin B; Penicillium nalgiovense Laxa; Antarctica; Medicinal Chemistry; Läkemedelskemi; Laxa; South Pole; Antarc*; South pole
• Online Access: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-242609; https://doi.org/10.1186/s40694-014-0011-x

Background: The need for new antibiotic drugs increases as pathogenic microorganisms continue to develop resistance against current antibiotics. We obtained samples from Antarctica as part of a search for new antimicrobial metabolites derived from filamentous fungi. This terrestrial environment in t...