Pheromonal Mediated Behaviour and Endocrine Responses in Salmonids : The impact of Cypermethrin, Copper, and Glyphosate
The effects of cypermethrin, copper and glyphosate on the endocrine system and subsequent response to female pheromones were investigated in mature male brown trout (Salmo trutta) parr. Responses measured were the amount of strippable milt, blood plasma levels of both an androgen (11-ketotestosteron...
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Ekotoxikologi
2010
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ftuppsalauniv:oai:DiVA.org:uu-121848 2023-05-15T15:33:00+02:00 Pheromonal Mediated Behaviour and Endocrine Responses in Salmonids : The impact of Cypermethrin, Copper, and Glyphosate Jaensson, Alia 2010 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-121848 eng eng Ekotoxikologi Uppsala : Acta Universitatis Upsaliensis Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, 1651-6214 730 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-121848 urn:isbn:978-91-554-7772-1 info:eu-repo/semantics/openAccess Cypermethrin copper glyphosate behaviour hormones pheromones olfaction 11-ketotestosterone (11-KT) 17α 20β-dihydroxy-4-pregnen-3-one (17 20β-P) reproduction Pharmacology and Toxicology Farmakologi och toxikologi Doctoral thesis, comprehensive summary info:eu-repo/semantics/doctoralThesis text 2010 ftuppsalauniv 2023-02-23T21:58:00Z The effects of cypermethrin, copper and glyphosate on the endocrine system and subsequent response to female pheromones were investigated in mature male brown trout (Salmo trutta) parr. Responses measured were the amount of strippable milt, blood plasma levels of both an androgen (11-ketotestosterone (11-KT)) and a progestin (17α,20β-dihydroxy-4-pregnen-3-one (17,20b-P)), and behavioural changes. This was done in a two phased investigation where parr were exposed to one of the following via ambient water: 1) 0.1 or 1.0 μg L-1 cypermethrin, 2) 10 or 100 μg L-1 copper (Cu2+), or 3) 150 μg L-1 glyphosate for a 96 hour period. Phase one was a priming experiment exposing parr to a treatment followed by priming with PGF2α or ovarian fluid (OVF). Atlantic salmon (Salmo salar) parr were, also exposed to glyphosate during phase I. The second phase was centered on behavioural observations. Exposed parr were placed in a 35,000 L stream aquarium together with two ovulated females and four anadromous males. After the experiments a blood sample was taken, milt volumes measured and testes weighed. The plasma was analyzed for 11-KT and 17,20b-P concentrations using radioimmunoassay (RIA). Results from phase I-priming: 1.0 μg L-1 cypermethrin exposure lowered 17,20b-P and 11-KT; Copper exposure lowered milt volumes; glyphosate exposure lowered 11-KT in salmon and raised 17,20b-P in trout. Results from phase II-behaviour: 1.0 μg L-1 cypermethrin exposure lowered 11-KT, milt and spawning behaviour; copper exposure lowered spawning behaviour and raised 11-KT; Glyphosate exposure lowered 11KT; continuous cypermethrin exposure raised 17,20b-P, 11-KT and gave a tendency towards increased aggression. It is concluded that low concentration exposure to the compounds examined can induce negative effects on male salmonid endocrine systems, either through a disruption in the olfactory system or through a direct effect. Extern doktorand från Södertörns högskola Doctoral or Postdoctoral Thesis Atlantic salmon Salmo salar Uppsala University: Publications (DiVA) |
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Uppsala University: Publications (DiVA) |
op_collection_id |
ftuppsalauniv |
language |
English |
topic |
Cypermethrin copper glyphosate behaviour hormones pheromones olfaction 11-ketotestosterone (11-KT) 17α 20β-dihydroxy-4-pregnen-3-one (17 20β-P) reproduction Pharmacology and Toxicology Farmakologi och toxikologi |
spellingShingle |
Cypermethrin copper glyphosate behaviour hormones pheromones olfaction 11-ketotestosterone (11-KT) 17α 20β-dihydroxy-4-pregnen-3-one (17 20β-P) reproduction Pharmacology and Toxicology Farmakologi och toxikologi Jaensson, Alia Pheromonal Mediated Behaviour and Endocrine Responses in Salmonids : The impact of Cypermethrin, Copper, and Glyphosate |
topic_facet |
Cypermethrin copper glyphosate behaviour hormones pheromones olfaction 11-ketotestosterone (11-KT) 17α 20β-dihydroxy-4-pregnen-3-one (17 20β-P) reproduction Pharmacology and Toxicology Farmakologi och toxikologi |
description |
The effects of cypermethrin, copper and glyphosate on the endocrine system and subsequent response to female pheromones were investigated in mature male brown trout (Salmo trutta) parr. Responses measured were the amount of strippable milt, blood plasma levels of both an androgen (11-ketotestosterone (11-KT)) and a progestin (17α,20β-dihydroxy-4-pregnen-3-one (17,20b-P)), and behavioural changes. This was done in a two phased investigation where parr were exposed to one of the following via ambient water: 1) 0.1 or 1.0 μg L-1 cypermethrin, 2) 10 or 100 μg L-1 copper (Cu2+), or 3) 150 μg L-1 glyphosate for a 96 hour period. Phase one was a priming experiment exposing parr to a treatment followed by priming with PGF2α or ovarian fluid (OVF). Atlantic salmon (Salmo salar) parr were, also exposed to glyphosate during phase I. The second phase was centered on behavioural observations. Exposed parr were placed in a 35,000 L stream aquarium together with two ovulated females and four anadromous males. After the experiments a blood sample was taken, milt volumes measured and testes weighed. The plasma was analyzed for 11-KT and 17,20b-P concentrations using radioimmunoassay (RIA). Results from phase I-priming: 1.0 μg L-1 cypermethrin exposure lowered 17,20b-P and 11-KT; Copper exposure lowered milt volumes; glyphosate exposure lowered 11-KT in salmon and raised 17,20b-P in trout. Results from phase II-behaviour: 1.0 μg L-1 cypermethrin exposure lowered 11-KT, milt and spawning behaviour; copper exposure lowered spawning behaviour and raised 11-KT; Glyphosate exposure lowered 11KT; continuous cypermethrin exposure raised 17,20b-P, 11-KT and gave a tendency towards increased aggression. It is concluded that low concentration exposure to the compounds examined can induce negative effects on male salmonid endocrine systems, either through a disruption in the olfactory system or through a direct effect. Extern doktorand från Södertörns högskola |
format |
Doctoral or Postdoctoral Thesis |
author |
Jaensson, Alia |
author_facet |
Jaensson, Alia |
author_sort |
Jaensson, Alia |
title |
Pheromonal Mediated Behaviour and Endocrine Responses in Salmonids : The impact of Cypermethrin, Copper, and Glyphosate |
title_short |
Pheromonal Mediated Behaviour and Endocrine Responses in Salmonids : The impact of Cypermethrin, Copper, and Glyphosate |
title_full |
Pheromonal Mediated Behaviour and Endocrine Responses in Salmonids : The impact of Cypermethrin, Copper, and Glyphosate |
title_fullStr |
Pheromonal Mediated Behaviour and Endocrine Responses in Salmonids : The impact of Cypermethrin, Copper, and Glyphosate |
title_full_unstemmed |
Pheromonal Mediated Behaviour and Endocrine Responses in Salmonids : The impact of Cypermethrin, Copper, and Glyphosate |
title_sort |
pheromonal mediated behaviour and endocrine responses in salmonids : the impact of cypermethrin, copper, and glyphosate |
publisher |
Ekotoxikologi |
publishDate |
2010 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-121848 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_relation |
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, 1651-6214 730 http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-121848 urn:isbn:978-91-554-7772-1 |
op_rights |
info:eu-repo/semantics/openAccess |
_version_ |
1766363472493281280 |