Protein polymorphism in northern populations of field mice (Apodemus sylvaticus L.)

• Main Author: Arnason, A.
• Format: Doctoral or Postdoctoral Thesis
• Language: unknown
• Published: 1974
• Subjects: Iceland
• Online Access: https://doi.org/10.48730/mdyk-1370; https://stax.strath.ac.uk/concern/theses/mp48sc79x

An electrophoretic investigation was carried out on protein variation in different tissues of Apodemus sylvaticus. In addition to some ontogenetic studies, physicochemical methods were employed to characterise esterase enzymes and other proteins. The distribution of variant forms from thirteen localities in Iceland, Ireland, Scotland, Norway and Sweden were studied. Finally it was possible in some cases to acquire breeding data and clarify modes of inheritance. Protein: Serum pre-albumins, albumin and ceruloplasmin are monomorphic, whilst post-albumin and transferring may be polymorphic. R-cell proteins A and B are polymorphic. Other tissue proteins were found to be uniform, except for a cathodally migrating protein fraction in striated muscle. Esterases: Most esterase fractions were found to be nonspecific carboxylesterases. Each tissue has its own esterase pattern, but also shares fractions with other tissues. The physicochemical tests, breeding, ontogenetic and population data make it feasable to propose a mode of inheritance for many esterase fractions. Thus, the proposed loci Es-1, Es-2, Es-3, Es-4, Es-7 and Es-8 have each two codominant alleles. Es-6 has one dominant silent allele, and one recessive producing allele. These loci produce esterase in more than one tissue at the same time. There is a difference between all populations tested, the Iceland populations differing most from the rest. It is suggested that chance founder effects is the chief factor for the uneven/uneven distribution of protein markers. The phvsicochemical characters of proteins in Apodemus sylvatcus are similar to those established for other rodents. An electrophoretic investigation was carried out on protein variation in different tissues of Apodemus sylvaticus. In addition to some ontogenetic studies, physicochemical methods were employed to characterise esterase enzymes and other proteins. The distribution of variant forms from thirteen localities in Iceland, Ireland, Scotland, Norway and Sweden were studied. Finally it was ...