Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries
A total of 94 European eels (Anguilla anguilla) were collected from five estuaries in the UK. The deconjugated metabolites of polycyclic aromatic hydrocarbons (PAHs) in the bile of the eels were separated using HPLC. Six PAH metabolites were identified: 1-hydroxy (1-OH) metabolites of phenanthrene,...
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ftuniwestengland:oai:eprints.uwe.ac.uk:7015 2023-05-15T13:26:55+02:00 Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries Ruddock, P. Bird, D. J. McEvoy, J. Peters, L. D. 2003-01 http://eprints.uwe.ac.uk/7015/ https://doi.org/10.1016/S0048-9697(02)00292-9 unknown Elsevier Ruddock, P. , Bird, D. J. , McEvoy, J. and Peters, L. D. (2003) Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries. The Science of The Total Environment, 301 (1-3). pp. 105-117. ISSN 0048-9697 Available from: http://eprints.uwe.ac.uk/7015 Article NonPeerReviewed 2003 ftuniwestengland https://doi.org/10.1016/S0048-9697(02)00292-9 2020-08-21T16:02:01Z A total of 94 European eels (Anguilla anguilla) were collected from five estuaries in the UK. The deconjugated metabolites of polycyclic aromatic hydrocarbons (PAHs) in the bile of the eels were separated using HPLC. Six PAH metabolites were identified: 1-hydroxy (1-OH) metabolites of phenanthrene, pyrene and chrysene; and the 1-OH, 3-OH and 7,8 dihydrodiol metabolites of benzo[a]pyrene (BaP). The mean concentration of the six metabolites was greatest in eels from the Tyne (49 μM) followed by the Wear (33 μM), Tees (19 μM), Thames (4 μM) and Severn (2 μM) estuaries. Although 1-OH pyrene was always the dominant compound, there were significant differences (P<0.05) between sites and between estuaries for some metabolites. Normalising the molar concentration of the bile metabolites to the bile biliverdin absorbance reduced sample variation. When the metabolites identified were each expressed as a percentage of the total detected, the metabolite profile was characteristic for each estuary. Article in Journal/Newspaper Anguilla anguilla University of the West of England, Bristol: UWE Research Repository Science of The Total Environment 301 1-3 105 117 |
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Open Polar |
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University of the West of England, Bristol: UWE Research Repository |
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ftuniwestengland |
language |
unknown |
description |
A total of 94 European eels (Anguilla anguilla) were collected from five estuaries in the UK. The deconjugated metabolites of polycyclic aromatic hydrocarbons (PAHs) in the bile of the eels were separated using HPLC. Six PAH metabolites were identified: 1-hydroxy (1-OH) metabolites of phenanthrene, pyrene and chrysene; and the 1-OH, 3-OH and 7,8 dihydrodiol metabolites of benzo[a]pyrene (BaP). The mean concentration of the six metabolites was greatest in eels from the Tyne (49 μM) followed by the Wear (33 μM), Tees (19 μM), Thames (4 μM) and Severn (2 μM) estuaries. Although 1-OH pyrene was always the dominant compound, there were significant differences (P<0.05) between sites and between estuaries for some metabolites. Normalising the molar concentration of the bile metabolites to the bile biliverdin absorbance reduced sample variation. When the metabolites identified were each expressed as a percentage of the total detected, the metabolite profile was characteristic for each estuary. |
format |
Article in Journal/Newspaper |
author |
Ruddock, P. Bird, D. J. McEvoy, J. Peters, L. D. |
spellingShingle |
Ruddock, P. Bird, D. J. McEvoy, J. Peters, L. D. Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries |
author_facet |
Ruddock, P. Bird, D. J. McEvoy, J. Peters, L. D. |
author_sort |
Ruddock, P. |
title |
Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries |
title_short |
Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries |
title_full |
Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries |
title_fullStr |
Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries |
title_full_unstemmed |
Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries |
title_sort |
bile metabolites of polycyclic aromatic hydrocarbons (pahs) in european eels anguilla anguilla from united kingdom estuaries |
publisher |
Elsevier |
publishDate |
2003 |
url |
http://eprints.uwe.ac.uk/7015/ https://doi.org/10.1016/S0048-9697(02)00292-9 |
genre |
Anguilla anguilla |
genre_facet |
Anguilla anguilla |
op_relation |
Ruddock, P. , Bird, D. J. , McEvoy, J. and Peters, L. D. (2003) Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries. The Science of The Total Environment, 301 (1-3). pp. 105-117. ISSN 0048-9697 Available from: http://eprints.uwe.ac.uk/7015 |
op_doi |
https://doi.org/10.1016/S0048-9697(02)00292-9 |
container_title |
Science of The Total Environment |
container_volume |
301 |
container_issue |
1-3 |
container_start_page |
105 |
op_container_end_page |
117 |
_version_ |
1766395288053874688 |