Genomic evidence for the Pleistocene and recent population history of Native Americans
INTRODUCTION: The consensus view on the peopling of the Americas is that ancestors of modern Native Americans entered the Americas from Siberia via the Bering Land Bridge and that this occurred at least ~14.6 thousand years ago (ka). However, the number and timing of migrations into the Americas rem...
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ftunivzuerich:oai:www.zora.uzh.ch:120402 2024-06-23T07:51:43+00:00 Genomic evidence for the Pleistocene and recent population history of Native Americans Raghavan, M Steinrucken, M Harris, K Schiffels, S Rasmussen, S DeGiorgio, M Zollikofer, C P E Ponce de León, M S Willerslev, E 2015 application/pdf https://www.zora.uzh.ch/id/eprint/120402/ https://www.zora.uzh.ch/id/eprint/120402/1/aab3884.full.pdf https://doi.org/10.5167/uzh-120402 https://doi.org/10.1126/science.aab3884 eng eng American Association for the Advancement of Science https://www.zora.uzh.ch/id/eprint/120402/1/aab3884.full.pdf doi:10.5167/uzh-120402 doi:10.1126/science.aab3884 info:pmid/26198033 urn:issn:0036-8075 info:eu-repo/semantics/closedAccess Raghavan, M; Steinrucken, M; Harris, K; Schiffels, S; Rasmussen, S; DeGiorgio, M; Zollikofer, C P E; Ponce de León, M S; Willerslev, E; et al (2015). Genomic evidence for the Pleistocene and recent population history of Native Americans. Science, 349(6250):aab3884-aab3884. Department of Evolutionary Anthropology 300 Social sciences sociology & anthropology Journal Article PeerReviewed info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2015 ftunivzuerich https://doi.org/10.5167/uzh-12040210.1126/science.aab3884 2024-05-29T00:30:37Z INTRODUCTION: The consensus view on the peopling of the Americas is that ancestors of modern Native Americans entered the Americas from Siberia via the Bering Land Bridge and that this occurred at least ~14.6 thousand years ago (ka). However, the number and timing of migrations into the Americas remain controversial, with conflicting interpretations based on anatomical and genetic evidence. RATIONALE: In this study, we address four major unresolved issues regarding the Pleistocene and recent population history of Native Americans: (i) the timing of their divergence from their ancestral group, (ii) the number of migrations into the Americas, (iii) whether there was ~15,000 years of isolation of ancestral Native Americans in Beringia (Beringian Incubation Model), and (iv) whether there was post-Pleistocene survival of relict populations in the Americas related to Australo-Melanesians, as suggested by apparent differences in cranial morphologies between some early (“Paleoamerican”) remains and those of more recent Native Americans. We generated 31 high-coverage modern genomes from the Americas, Siberia, and Oceania; 23 ancient genomic sequences from the Americas dating between ~0.2 and 6 ka; and SNP chip genotype data from 79 present-day individuals belonging to 28 populations from the Americas and Siberia. The above data sets were analyzed together with published modern and ancient genomic data from worldwide populations, after masking some present-day Native Americans for recent European admixture. RESULTS: Using three different methods, we determined the divergence time for all Native Americans (Athabascans and Amerindians) from their Siberian ancestors to be ~20 ka, and no earlier than ~23 ka. Furthermore, we dated the divergence between Athabascans (northern Native American branch, together with northern North American Amerindians) and southern North Americans and South and Central Americans (southern Native American branch) to be ~13 ka. Similar divergence times from East Asian populations and a divergence ... Article in Journal/Newspaper Bering Land Bridge Beringia Siberia University of Zurich (UZH): ZORA (Zurich Open Repository and Archive Frontiers in Plant Science 13 |
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University of Zurich (UZH): ZORA (Zurich Open Repository and Archive |
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ftunivzuerich |
language |
English |
topic |
Department of Evolutionary Anthropology 300 Social sciences sociology & anthropology |
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Department of Evolutionary Anthropology 300 Social sciences sociology & anthropology Raghavan, M Steinrucken, M Harris, K Schiffels, S Rasmussen, S DeGiorgio, M Zollikofer, C P E Ponce de León, M S Willerslev, E Genomic evidence for the Pleistocene and recent population history of Native Americans |
topic_facet |
Department of Evolutionary Anthropology 300 Social sciences sociology & anthropology |
description |
INTRODUCTION: The consensus view on the peopling of the Americas is that ancestors of modern Native Americans entered the Americas from Siberia via the Bering Land Bridge and that this occurred at least ~14.6 thousand years ago (ka). However, the number and timing of migrations into the Americas remain controversial, with conflicting interpretations based on anatomical and genetic evidence. RATIONALE: In this study, we address four major unresolved issues regarding the Pleistocene and recent population history of Native Americans: (i) the timing of their divergence from their ancestral group, (ii) the number of migrations into the Americas, (iii) whether there was ~15,000 years of isolation of ancestral Native Americans in Beringia (Beringian Incubation Model), and (iv) whether there was post-Pleistocene survival of relict populations in the Americas related to Australo-Melanesians, as suggested by apparent differences in cranial morphologies between some early (“Paleoamerican”) remains and those of more recent Native Americans. We generated 31 high-coverage modern genomes from the Americas, Siberia, and Oceania; 23 ancient genomic sequences from the Americas dating between ~0.2 and 6 ka; and SNP chip genotype data from 79 present-day individuals belonging to 28 populations from the Americas and Siberia. The above data sets were analyzed together with published modern and ancient genomic data from worldwide populations, after masking some present-day Native Americans for recent European admixture. RESULTS: Using three different methods, we determined the divergence time for all Native Americans (Athabascans and Amerindians) from their Siberian ancestors to be ~20 ka, and no earlier than ~23 ka. Furthermore, we dated the divergence between Athabascans (northern Native American branch, together with northern North American Amerindians) and southern North Americans and South and Central Americans (southern Native American branch) to be ~13 ka. Similar divergence times from East Asian populations and a divergence ... |
format |
Article in Journal/Newspaper |
author |
Raghavan, M Steinrucken, M Harris, K Schiffels, S Rasmussen, S DeGiorgio, M Zollikofer, C P E Ponce de León, M S Willerslev, E |
author_facet |
Raghavan, M Steinrucken, M Harris, K Schiffels, S Rasmussen, S DeGiorgio, M Zollikofer, C P E Ponce de León, M S Willerslev, E |
author_sort |
Raghavan, M |
title |
Genomic evidence for the Pleistocene and recent population history of Native Americans |
title_short |
Genomic evidence for the Pleistocene and recent population history of Native Americans |
title_full |
Genomic evidence for the Pleistocene and recent population history of Native Americans |
title_fullStr |
Genomic evidence for the Pleistocene and recent population history of Native Americans |
title_full_unstemmed |
Genomic evidence for the Pleistocene and recent population history of Native Americans |
title_sort |
genomic evidence for the pleistocene and recent population history of native americans |
publisher |
American Association for the Advancement of Science |
publishDate |
2015 |
url |
https://www.zora.uzh.ch/id/eprint/120402/ https://www.zora.uzh.ch/id/eprint/120402/1/aab3884.full.pdf https://doi.org/10.5167/uzh-120402 https://doi.org/10.1126/science.aab3884 |
genre |
Bering Land Bridge Beringia Siberia |
genre_facet |
Bering Land Bridge Beringia Siberia |
op_source |
Raghavan, M; Steinrucken, M; Harris, K; Schiffels, S; Rasmussen, S; DeGiorgio, M; Zollikofer, C P E; Ponce de León, M S; Willerslev, E; et al (2015). Genomic evidence for the Pleistocene and recent population history of Native Americans. Science, 349(6250):aab3884-aab3884. |
op_relation |
https://www.zora.uzh.ch/id/eprint/120402/1/aab3884.full.pdf doi:10.5167/uzh-120402 doi:10.1126/science.aab3884 info:pmid/26198033 urn:issn:0036-8075 |
op_rights |
info:eu-repo/semantics/closedAccess |
op_doi |
https://doi.org/10.5167/uzh-12040210.1126/science.aab3884 |
container_title |
Frontiers in Plant Science |
container_volume |
13 |
_version_ |
1802642840908464128 |