Hazards of secondary bromadiolone intoxications evaluated using high-performance liquid chromatography with electrochemical detection
This study reported on the possibility of intoxications of non-target wild animals associated with use of bromadiolone as the active component of rodenticides with anticoagulation effects. A laboratory test was done with earthworms were exposed to bromadiolone-containing granules under the condition...
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Molecular Diversity Preservation International (MDPI)
2007
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ftunivzlinpubl:oai:publikace.k.utb.cz:10563/1002108 2023-07-16T03:59:31+02:00 Hazards of secondary bromadiolone intoxications evaluated using high-performance liquid chromatography with electrochemical detection Křížková, Soňa Beklová, Miroslava Pikula, Jiří Adam, Vojtěch Horna, Aleš Kizek, René 2007-07 http://publikace.k.utb.cz/handle/10563/1002108 en eng Molecular Diversity Preservation International (MDPI) http://www.mdpi.com/1424-8220/7/7/1271/ Sensors http://publikace.k.utb.cz/handle/10563/1002108 Attribution 3.0 International https://creativecommons.org/licenses/by/3.0/ openAccess Sensors anticoagulant rodenticide electrochemistry cyclic voltammetry animal tissues non-target organisms Eisenia fetida Microtus arvalis Lepus europaeus article 2007 ftunivzlinpubl 2023-06-25T07:40:02Z This study reported on the possibility of intoxications of non-target wild animals associated with use of bromadiolone as the active component of rodenticides with anticoagulation effects. A laboratory test was done with earthworms were exposed to bromadiolone-containing granules under the conditions specified in the modified OECD 207 guideline. No mortality of earthworms was observed during the fourteen days long exposure. When the earthworms from the above test became a part of the diet of common voles in the following experiment, no mortality of consumers was observed too. However, electrochemical analysis revealed higher levels of bromadiolone in tissues from earthworms as well as common voles compared to control animals. There were determined comparable levels of bromadiolone in the liver tissue of common voles after primary (2.34 +/- 0.10 mu g/g) and secondary (2.20 +/- 0.53 mu g/g) intoxication. Therefore, the risk of secondary intoxication of small mammalian species feeding on bromadiolone-containing earthworms is the same as of primary intoxication through baited granules. Bromadiolone bio- accumulation in the food chain was monitored using the newly developed analytical procedure based on the use of a liquid chromatography coupled with electrochemical detector (HPLC-ED). The HPLC-ED method allowed to determine the levels of bromadiolone in biological samples and is therefore suitable for examining the environmental hazards of this substance. Article in Journal/Newspaper Microtus arvalis Tomas Bata University Zlin: TBU publications |
institution |
Open Polar |
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Tomas Bata University Zlin: TBU publications |
op_collection_id |
ftunivzlinpubl |
language |
English |
topic |
anticoagulant rodenticide electrochemistry cyclic voltammetry animal tissues non-target organisms Eisenia fetida Microtus arvalis Lepus europaeus |
spellingShingle |
anticoagulant rodenticide electrochemistry cyclic voltammetry animal tissues non-target organisms Eisenia fetida Microtus arvalis Lepus europaeus Křížková, Soňa Beklová, Miroslava Pikula, Jiří Adam, Vojtěch Horna, Aleš Kizek, René Hazards of secondary bromadiolone intoxications evaluated using high-performance liquid chromatography with electrochemical detection |
topic_facet |
anticoagulant rodenticide electrochemistry cyclic voltammetry animal tissues non-target organisms Eisenia fetida Microtus arvalis Lepus europaeus |
description |
This study reported on the possibility of intoxications of non-target wild animals associated with use of bromadiolone as the active component of rodenticides with anticoagulation effects. A laboratory test was done with earthworms were exposed to bromadiolone-containing granules under the conditions specified in the modified OECD 207 guideline. No mortality of earthworms was observed during the fourteen days long exposure. When the earthworms from the above test became a part of the diet of common voles in the following experiment, no mortality of consumers was observed too. However, electrochemical analysis revealed higher levels of bromadiolone in tissues from earthworms as well as common voles compared to control animals. There were determined comparable levels of bromadiolone in the liver tissue of common voles after primary (2.34 +/- 0.10 mu g/g) and secondary (2.20 +/- 0.53 mu g/g) intoxication. Therefore, the risk of secondary intoxication of small mammalian species feeding on bromadiolone-containing earthworms is the same as of primary intoxication through baited granules. Bromadiolone bio- accumulation in the food chain was monitored using the newly developed analytical procedure based on the use of a liquid chromatography coupled with electrochemical detector (HPLC-ED). The HPLC-ED method allowed to determine the levels of bromadiolone in biological samples and is therefore suitable for examining the environmental hazards of this substance. |
format |
Article in Journal/Newspaper |
author |
Křížková, Soňa Beklová, Miroslava Pikula, Jiří Adam, Vojtěch Horna, Aleš Kizek, René |
author_facet |
Křížková, Soňa Beklová, Miroslava Pikula, Jiří Adam, Vojtěch Horna, Aleš Kizek, René |
author_sort |
Křížková, Soňa |
title |
Hazards of secondary bromadiolone intoxications evaluated using high-performance liquid chromatography with electrochemical detection |
title_short |
Hazards of secondary bromadiolone intoxications evaluated using high-performance liquid chromatography with electrochemical detection |
title_full |
Hazards of secondary bromadiolone intoxications evaluated using high-performance liquid chromatography with electrochemical detection |
title_fullStr |
Hazards of secondary bromadiolone intoxications evaluated using high-performance liquid chromatography with electrochemical detection |
title_full_unstemmed |
Hazards of secondary bromadiolone intoxications evaluated using high-performance liquid chromatography with electrochemical detection |
title_sort |
hazards of secondary bromadiolone intoxications evaluated using high-performance liquid chromatography with electrochemical detection |
publisher |
Molecular Diversity Preservation International (MDPI) |
publishDate |
2007 |
url |
http://publikace.k.utb.cz/handle/10563/1002108 |
genre |
Microtus arvalis |
genre_facet |
Microtus arvalis |
op_source |
Sensors |
op_relation |
http://www.mdpi.com/1424-8220/7/7/1271/ Sensors http://publikace.k.utb.cz/handle/10563/1002108 |
op_rights |
Attribution 3.0 International https://creativecommons.org/licenses/by/3.0/ openAccess |
_version_ |
1771547314596347904 |