Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS
Per- and polyfluoroalkyl substances (PFAS) are a group of emerging substances that have proved to be persistent and highly bioaccumulative. They are broadly used in various applications and are known for their long-distance migration and toxicity. In this study, 65 recent specimens of a terrestrial...
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2022
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Online Access: | https://research.wur.nl/en/publications/determination-of-56-per-and-polyfluoroalkyl-substances-in-top-pre https://doi.org/10.1016/j.chemosphere.2021.131775 |
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ftunivwagenin:oai:library.wur.nl:wurpubs/587003 2024-04-28T08:22:59+00:00 Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS Androulakakis, Andreas Alygizakis, Nikiforos Gkotsis, Georgios Nika, Maria Christina Nikolopoulou, Varvara Bizani, Erasmia Chadwick, Elizabeth Cincinelli, Alessandra Claßen, Daniela Danielsson, Sara Dekker, Rene W.R.J. Duke, Guy Glowacka, Natalia Jansman, Hugh A.H. Krone, Oliver Martellini, Tania Movalli, Paola Persson, Sara Roos, Anna O'Rourke, Emily Siebert, Ursula Treu, Gabriele van den Brink, Nico W. Walker, Lee Anthony Deaville, Rob Slobodnik, Jaroslav Thomaidis, Nikolaos S. 2022 application/pdf https://research.wur.nl/en/publications/determination-of-56-per-and-polyfluoroalkyl-substances-in-top-pre https://doi.org/10.1016/j.chemosphere.2021.131775 en eng https://edepot.wur.nl/553873 https://research.wur.nl/en/publications/determination-of-56-per-and-polyfluoroalkyl-substances-in-top-pre doi:10.1016/j.chemosphere.2021.131775 Wageningen University & Research Chemosphere 287 (2022) ISSN: 0045-6535 Buzzard Grey seal Harbour porpoise Harbour seal LC-MS/MS Otter PFAS Article/Letter to editor 2022 ftunivwagenin https://doi.org/10.1016/j.chemosphere.2021.131775 2024-04-03T14:58:12Z Per- and polyfluoroalkyl substances (PFAS) are a group of emerging substances that have proved to be persistent and highly bioaccumulative. They are broadly used in various applications and are known for their long-distance migration and toxicity. In this study, 65 recent specimens of a terrestrial apex predator (Common buzzard), freshwater and marine apex predators (Eurasian otter, harbour porpoise, grey seal, harbour seal) and their potential prey (bream, roach, herring, eelpout) from northern Europe (United Kingdom, Germany, the Netherlands and Sweden) were analyzed for the presence of legacy and emerging PFAS, employing a highly sensitive liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) method. 56 compounds from 14 classes were measured; 13 perfluoroalkyl carboxylic acids (PFCAs), 7 perfluoroalkyl sulphonic acids (PFSAs), 3 perfluorooctane sulfonamides (FOSAs), 4 perfluoroalkylphosphonic acids (PFAPAs), 3 perfluoroalkylphosphinic acids (PFPi's), 5 telomer alcohols (FTOHs), 2 mono-substituted polyfluorinated phosphate esters (PAPs), 2 di-substituted polyfluorinated phosphate esters (diPAPs), 6 saturated fluorotelomer acids (FTAS), 3 unsaturated fluorotelomer acids (FTUAs), 2 N-Alkyl perfluorooctane sulfonamidoethanols (FOSEs), 3 fluorotelomer sulphonic acids (FTSAs), 2 perfluoroether carboxylic acids (PFECAs) and 1 chlorinated perfluoroether sulphonic acid (Cl-PFESA). All samples were lyophilized before analysis, in order to enhance extraction efficiency, improve the precision and achieve lower detection limits. The analytes were extracted from the dry matrices through generic methods of extraction, using an accelerated solvent extraction (ASE), followed by clean-up through solid phase extraction (SPE). Method detection limits and method quantification limits ranged from 0.02 to 1.25 ng/g wet weight (ww) and from 0.05 to 3.79 ng/g (ww), respectively. Recovery ranged from 40 to 137%. Method precision ranged from 3 to 20 %RSD. The sum of PFAS concentration in apex predators ... Article in Journal/Newspaper Harbour porpoise harbour seal Wageningen UR (University & Research Centre): Digital Library Chemosphere 287 131775 |
institution |
Open Polar |
collection |
Wageningen UR (University & Research Centre): Digital Library |
op_collection_id |
ftunivwagenin |
language |
English |
topic |
Buzzard Grey seal Harbour porpoise Harbour seal LC-MS/MS Otter PFAS |
spellingShingle |
Buzzard Grey seal Harbour porpoise Harbour seal LC-MS/MS Otter PFAS Androulakakis, Andreas Alygizakis, Nikiforos Gkotsis, Georgios Nika, Maria Christina Nikolopoulou, Varvara Bizani, Erasmia Chadwick, Elizabeth Cincinelli, Alessandra Claßen, Daniela Danielsson, Sara Dekker, Rene W.R.J. Duke, Guy Glowacka, Natalia Jansman, Hugh A.H. Krone, Oliver Martellini, Tania Movalli, Paola Persson, Sara Roos, Anna O'Rourke, Emily Siebert, Ursula Treu, Gabriele van den Brink, Nico W. Walker, Lee Anthony Deaville, Rob Slobodnik, Jaroslav Thomaidis, Nikolaos S. Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS |
topic_facet |
Buzzard Grey seal Harbour porpoise Harbour seal LC-MS/MS Otter PFAS |
description |
Per- and polyfluoroalkyl substances (PFAS) are a group of emerging substances that have proved to be persistent and highly bioaccumulative. They are broadly used in various applications and are known for their long-distance migration and toxicity. In this study, 65 recent specimens of a terrestrial apex predator (Common buzzard), freshwater and marine apex predators (Eurasian otter, harbour porpoise, grey seal, harbour seal) and their potential prey (bream, roach, herring, eelpout) from northern Europe (United Kingdom, Germany, the Netherlands and Sweden) were analyzed for the presence of legacy and emerging PFAS, employing a highly sensitive liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) method. 56 compounds from 14 classes were measured; 13 perfluoroalkyl carboxylic acids (PFCAs), 7 perfluoroalkyl sulphonic acids (PFSAs), 3 perfluorooctane sulfonamides (FOSAs), 4 perfluoroalkylphosphonic acids (PFAPAs), 3 perfluoroalkylphosphinic acids (PFPi's), 5 telomer alcohols (FTOHs), 2 mono-substituted polyfluorinated phosphate esters (PAPs), 2 di-substituted polyfluorinated phosphate esters (diPAPs), 6 saturated fluorotelomer acids (FTAS), 3 unsaturated fluorotelomer acids (FTUAs), 2 N-Alkyl perfluorooctane sulfonamidoethanols (FOSEs), 3 fluorotelomer sulphonic acids (FTSAs), 2 perfluoroether carboxylic acids (PFECAs) and 1 chlorinated perfluoroether sulphonic acid (Cl-PFESA). All samples were lyophilized before analysis, in order to enhance extraction efficiency, improve the precision and achieve lower detection limits. The analytes were extracted from the dry matrices through generic methods of extraction, using an accelerated solvent extraction (ASE), followed by clean-up through solid phase extraction (SPE). Method detection limits and method quantification limits ranged from 0.02 to 1.25 ng/g wet weight (ww) and from 0.05 to 3.79 ng/g (ww), respectively. Recovery ranged from 40 to 137%. Method precision ranged from 3 to 20 %RSD. The sum of PFAS concentration in apex predators ... |
format |
Article in Journal/Newspaper |
author |
Androulakakis, Andreas Alygizakis, Nikiforos Gkotsis, Georgios Nika, Maria Christina Nikolopoulou, Varvara Bizani, Erasmia Chadwick, Elizabeth Cincinelli, Alessandra Claßen, Daniela Danielsson, Sara Dekker, Rene W.R.J. Duke, Guy Glowacka, Natalia Jansman, Hugh A.H. Krone, Oliver Martellini, Tania Movalli, Paola Persson, Sara Roos, Anna O'Rourke, Emily Siebert, Ursula Treu, Gabriele van den Brink, Nico W. Walker, Lee Anthony Deaville, Rob Slobodnik, Jaroslav Thomaidis, Nikolaos S. |
author_facet |
Androulakakis, Andreas Alygizakis, Nikiforos Gkotsis, Georgios Nika, Maria Christina Nikolopoulou, Varvara Bizani, Erasmia Chadwick, Elizabeth Cincinelli, Alessandra Claßen, Daniela Danielsson, Sara Dekker, Rene W.R.J. Duke, Guy Glowacka, Natalia Jansman, Hugh A.H. Krone, Oliver Martellini, Tania Movalli, Paola Persson, Sara Roos, Anna O'Rourke, Emily Siebert, Ursula Treu, Gabriele van den Brink, Nico W. Walker, Lee Anthony Deaville, Rob Slobodnik, Jaroslav Thomaidis, Nikolaos S. |
author_sort |
Androulakakis, Andreas |
title |
Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS |
title_short |
Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS |
title_full |
Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS |
title_fullStr |
Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS |
title_full_unstemmed |
Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS |
title_sort |
determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from northern europe by lc-ms/ms |
publishDate |
2022 |
url |
https://research.wur.nl/en/publications/determination-of-56-per-and-polyfluoroalkyl-substances-in-top-pre https://doi.org/10.1016/j.chemosphere.2021.131775 |
genre |
Harbour porpoise harbour seal |
genre_facet |
Harbour porpoise harbour seal |
op_source |
Chemosphere 287 (2022) ISSN: 0045-6535 |
op_relation |
https://edepot.wur.nl/553873 https://research.wur.nl/en/publications/determination-of-56-per-and-polyfluoroalkyl-substances-in-top-pre doi:10.1016/j.chemosphere.2021.131775 |
op_rights |
Wageningen University & Research |
op_doi |
https://doi.org/10.1016/j.chemosphere.2021.131775 |
container_title |
Chemosphere |
container_volume |
287 |
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131775 |
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1797584240604348416 |