Marine Sediments Illuminate Chlamydiae Diversity and Evolution
The bacterial phylum Chlamydiae is so far composed of obligate symbionts of eukaryotic hosts. Well known for Chlamydiaceae, pathogens of humans and other animals, Chlamydiae also include so-called environmental lineages that primarily infect microbial eukaryotes. Environmental surveys indicate that...
Published in: | Current Biology |
---|---|
Main Authors: | , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
2020
|
Subjects: | |
Online Access: | https://research.wur.nl/en/publications/marine-sediments-illuminate-chlamydiae-diversity-and-evolution https://doi.org/10.1016/j.cub.2020.02.016 |
id |
ftunivwagenin:oai:library.wur.nl:wurpubs/562924 |
---|---|
record_format |
openpolar |
spelling |
ftunivwagenin:oai:library.wur.nl:wurpubs/562924 2024-04-28T08:12:15+00:00 Marine Sediments Illuminate Chlamydiae Diversity and Evolution Dharamshi, Jennah E. Tamarit, Daniel Eme, Laura Stairs, Courtney W. Martijn, Joran Homa, Felix Jørgensen, Steffen L. Spang, Anja Ettema, Thijs J.G. 2020 application/pdf https://research.wur.nl/en/publications/marine-sediments-illuminate-chlamydiae-diversity-and-evolution https://doi.org/10.1016/j.cub.2020.02.016 en eng https://edepot.wur.nl/518815 https://research.wur.nl/en/publications/marine-sediments-illuminate-chlamydiae-diversity-and-evolution doi:10.1016/j.cub.2020.02.016 (c) publisher Wageningen University & Research Current Biology 30 (2020) 6 ISSN: 0960-9822 Chlamydia PVC superphylum anoxic marine sediment metagenomics microbe-host association microbial community microbial evolution symbiosis uncultured microbial diversity Article/Letter to editor 2020 ftunivwagenin https://doi.org/10.1016/j.cub.2020.02.016 2024-04-03T15:11:23Z The bacterial phylum Chlamydiae is so far composed of obligate symbionts of eukaryotic hosts. Well known for Chlamydiaceae, pathogens of humans and other animals, Chlamydiae also include so-called environmental lineages that primarily infect microbial eukaryotes. Environmental surveys indicate that Chlamydiae are found in a wider range of environments than anticipated previously. However, the vast majority of this chlamydial diversity has been underexplored, biasing our current understanding of their biology, ecological importance, and evolution. Here, we report that previously undetected and active chlamydial lineages dominate microbial communities in deep anoxic marine sediments taken from the Arctic Mid-Ocean Ridge. Reaching relative abundances of up to 43% of the bacterial community, and a maximum diversity of 163 different species-level taxonomic units, these Chlamydiae represent important community members. Using genome-resolved metagenomics, we reconstructed 24 draft chlamydial genomes, expanding by over a third the known genomic diversity in this phylum. Phylogenomic analyses revealed several novel clades across the phylum, including a previously unknown sister lineage of the Chlamydiaceae, providing new insights into the origin of pathogenicity in this family. We were unable to identify putative eukaryotic hosts for these marine sediment chlamydiae, despite identifying genomic features that may be indicative of host-association. The high abundance and genomic diversity of Chlamydiae in these anoxic marine sediments indicate that some members could play an important, and thus far overlooked, ecological role in such environments and may indicate alternate lifestyle strategies. Dharamshi et al. find abundant, diverse, and active Chlamydiae in deep anoxic marine sediments. Using metagenomics, chlamydial genomes are obtained that form several new clades. Analyses of these genomes provide new insights into the evolution and host association of the Chlamydiae phylum, indicating that some are not symbionts of ... Article in Journal/Newspaper Arctic Wageningen UR (University & Research Centre): Digital Library Current Biology 30 6 1032 1048.e7 |
institution |
Open Polar |
collection |
Wageningen UR (University & Research Centre): Digital Library |
op_collection_id |
ftunivwagenin |
language |
English |
topic |
Chlamydia PVC superphylum anoxic marine sediment metagenomics microbe-host association microbial community microbial evolution symbiosis uncultured microbial diversity |
spellingShingle |
Chlamydia PVC superphylum anoxic marine sediment metagenomics microbe-host association microbial community microbial evolution symbiosis uncultured microbial diversity Dharamshi, Jennah E. Tamarit, Daniel Eme, Laura Stairs, Courtney W. Martijn, Joran Homa, Felix Jørgensen, Steffen L. Spang, Anja Ettema, Thijs J.G. Marine Sediments Illuminate Chlamydiae Diversity and Evolution |
topic_facet |
Chlamydia PVC superphylum anoxic marine sediment metagenomics microbe-host association microbial community microbial evolution symbiosis uncultured microbial diversity |
description |
The bacterial phylum Chlamydiae is so far composed of obligate symbionts of eukaryotic hosts. Well known for Chlamydiaceae, pathogens of humans and other animals, Chlamydiae also include so-called environmental lineages that primarily infect microbial eukaryotes. Environmental surveys indicate that Chlamydiae are found in a wider range of environments than anticipated previously. However, the vast majority of this chlamydial diversity has been underexplored, biasing our current understanding of their biology, ecological importance, and evolution. Here, we report that previously undetected and active chlamydial lineages dominate microbial communities in deep anoxic marine sediments taken from the Arctic Mid-Ocean Ridge. Reaching relative abundances of up to 43% of the bacterial community, and a maximum diversity of 163 different species-level taxonomic units, these Chlamydiae represent important community members. Using genome-resolved metagenomics, we reconstructed 24 draft chlamydial genomes, expanding by over a third the known genomic diversity in this phylum. Phylogenomic analyses revealed several novel clades across the phylum, including a previously unknown sister lineage of the Chlamydiaceae, providing new insights into the origin of pathogenicity in this family. We were unable to identify putative eukaryotic hosts for these marine sediment chlamydiae, despite identifying genomic features that may be indicative of host-association. The high abundance and genomic diversity of Chlamydiae in these anoxic marine sediments indicate that some members could play an important, and thus far overlooked, ecological role in such environments and may indicate alternate lifestyle strategies. Dharamshi et al. find abundant, diverse, and active Chlamydiae in deep anoxic marine sediments. Using metagenomics, chlamydial genomes are obtained that form several new clades. Analyses of these genomes provide new insights into the evolution and host association of the Chlamydiae phylum, indicating that some are not symbionts of ... |
format |
Article in Journal/Newspaper |
author |
Dharamshi, Jennah E. Tamarit, Daniel Eme, Laura Stairs, Courtney W. Martijn, Joran Homa, Felix Jørgensen, Steffen L. Spang, Anja Ettema, Thijs J.G. |
author_facet |
Dharamshi, Jennah E. Tamarit, Daniel Eme, Laura Stairs, Courtney W. Martijn, Joran Homa, Felix Jørgensen, Steffen L. Spang, Anja Ettema, Thijs J.G. |
author_sort |
Dharamshi, Jennah E. |
title |
Marine Sediments Illuminate Chlamydiae Diversity and Evolution |
title_short |
Marine Sediments Illuminate Chlamydiae Diversity and Evolution |
title_full |
Marine Sediments Illuminate Chlamydiae Diversity and Evolution |
title_fullStr |
Marine Sediments Illuminate Chlamydiae Diversity and Evolution |
title_full_unstemmed |
Marine Sediments Illuminate Chlamydiae Diversity and Evolution |
title_sort |
marine sediments illuminate chlamydiae diversity and evolution |
publishDate |
2020 |
url |
https://research.wur.nl/en/publications/marine-sediments-illuminate-chlamydiae-diversity-and-evolution https://doi.org/10.1016/j.cub.2020.02.016 |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Current Biology 30 (2020) 6 ISSN: 0960-9822 |
op_relation |
https://edepot.wur.nl/518815 https://research.wur.nl/en/publications/marine-sediments-illuminate-chlamydiae-diversity-and-evolution doi:10.1016/j.cub.2020.02.016 |
op_rights |
(c) publisher Wageningen University & Research |
op_doi |
https://doi.org/10.1016/j.cub.2020.02.016 |
container_title |
Current Biology |
container_volume |
30 |
container_issue |
6 |
container_start_page |
1032 |
op_container_end_page |
1048.e7 |
_version_ |
1797579191390044160 |