Occurrence of pharmaceuticals and endocrine disrupting compounds in macroalgaes, bivalves, and fish from coastal areas in Europe
The ocurrence and levels of PhACs, Endocrine Disrupting and related Compounds (EDCs) in seafood from potential contaminated areas in Europe has been studied. Macroalgae (S. accharina latissima and Laminaria digitata), bivalves (Mytilus galloprovincialis, Mytilus spp., Chamalea gallina and Crassostre...
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Online Access: | https://research.wur.nl/en/publications/occurrence-of-pharmaceuticals-and-endocrine-disrupting-compounds- https://doi.org/10.1016/j.envres.2015.09.018 |
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ftunivwagenin:oai:library.wur.nl:wurpubs/498165 2024-01-14T10:06:19+01:00 Occurrence of pharmaceuticals and endocrine disrupting compounds in macroalgaes, bivalves, and fish from coastal areas in Europe Álvarez-Muñoz, D. Rodríguez-Mozaz, S. Maulvault, A.L. Tediosi, A. Fernández-Tejedor, M. Van den Heuvel, F. Kotterman, M. Marques, A. Barceló, D. 2015 application/pdf https://research.wur.nl/en/publications/occurrence-of-pharmaceuticals-and-endocrine-disrupting-compounds- https://doi.org/10.1016/j.envres.2015.09.018 en eng info:eu-repo/grantAgreement/EC/FP7/311820 https://edepot.wur.nl/374759 https://research.wur.nl/en/publications/occurrence-of-pharmaceuticals-and-endocrine-disrupting-compounds- doi:10.1016/j.envres.2015.09.018 info:eu-repo/semantics/restrictedAccess Wageningen University & Research Environmental Research 143 (2015) ISSN: 0013-9351 Algae Bivalves Endocrine disrupting compounds Fish Pharmaceutical Prioritisation info:eu-repo/semantics/article Article/Letter to editor info:eu-repo/semantics/publishedVersion 2015 ftunivwagenin https://doi.org/10.1016/j.envres.2015.09.018 2023-12-20T23:17:59Z The ocurrence and levels of PhACs, Endocrine Disrupting and related Compounds (EDCs) in seafood from potential contaminated areas in Europe has been studied. Macroalgae (S. accharina latissima and Laminaria digitata), bivalves (Mytilus galloprovincialis, Mytilus spp., Chamalea gallina and Crassostrea gigas) and fish (Liza aurata and Platichthys flesus) from Portugal, Spain, Italy, Netherlands, and Norway were analysed following 4 different analytical protocols depending on the organism and target group of contaminants. The results revealed the presence of 4 pharmaceutical compounds in macroalgae samples, 16 in bivalves and 10 in fish. To the best of our knowledge, this is the first time that PhACs have been detected in marine fish and in macroalgae. Besides, this is also the first time that dimetridazole, hydrochlorothiazide and tamsulosin have been detected in biota samples. The highest levels of PhACs corresponded to the psychiatric drug velanfaxine (up to 36.1 ng/g dry weight (dw)) and the antibiotic azithromycin (up to 13.3 ng/g dw) in bivalves from the Po delta (Italy). EDCs were not detected in macroalgae samples, however, the analysis revealed the presence of 10 EDCs in bivalves and 8 in fish. The highest levels corresponded to the organophosphorus flame retardant tris(2-butoxyethyl)phosphate (TBEP) reaching up to 98.4 ng/g dw in mullet fish from the Tagus estuary. Bivalves, in particular mussels, have shown to be good bioindicator organisms for PhACs and fish for EDCs. Taking into consideration the concentrations and frequencies of detection of PhACs and EDCs in the seafood samples analysed, a list of candidates' compounds for priorization in future studies has been proposed. Article in Journal/Newspaper Crassostrea gigas Wageningen UR (University & Research Centre): Digital Library Norway Environmental Research 143 56 64 |
institution |
Open Polar |
collection |
Wageningen UR (University & Research Centre): Digital Library |
op_collection_id |
ftunivwagenin |
language |
English |
topic |
Algae Bivalves Endocrine disrupting compounds Fish Pharmaceutical Prioritisation |
spellingShingle |
Algae Bivalves Endocrine disrupting compounds Fish Pharmaceutical Prioritisation Álvarez-Muñoz, D. Rodríguez-Mozaz, S. Maulvault, A.L. Tediosi, A. Fernández-Tejedor, M. Van den Heuvel, F. Kotterman, M. Marques, A. Barceló, D. Occurrence of pharmaceuticals and endocrine disrupting compounds in macroalgaes, bivalves, and fish from coastal areas in Europe |
topic_facet |
Algae Bivalves Endocrine disrupting compounds Fish Pharmaceutical Prioritisation |
description |
The ocurrence and levels of PhACs, Endocrine Disrupting and related Compounds (EDCs) in seafood from potential contaminated areas in Europe has been studied. Macroalgae (S. accharina latissima and Laminaria digitata), bivalves (Mytilus galloprovincialis, Mytilus spp., Chamalea gallina and Crassostrea gigas) and fish (Liza aurata and Platichthys flesus) from Portugal, Spain, Italy, Netherlands, and Norway were analysed following 4 different analytical protocols depending on the organism and target group of contaminants. The results revealed the presence of 4 pharmaceutical compounds in macroalgae samples, 16 in bivalves and 10 in fish. To the best of our knowledge, this is the first time that PhACs have been detected in marine fish and in macroalgae. Besides, this is also the first time that dimetridazole, hydrochlorothiazide and tamsulosin have been detected in biota samples. The highest levels of PhACs corresponded to the psychiatric drug velanfaxine (up to 36.1 ng/g dry weight (dw)) and the antibiotic azithromycin (up to 13.3 ng/g dw) in bivalves from the Po delta (Italy). EDCs were not detected in macroalgae samples, however, the analysis revealed the presence of 10 EDCs in bivalves and 8 in fish. The highest levels corresponded to the organophosphorus flame retardant tris(2-butoxyethyl)phosphate (TBEP) reaching up to 98.4 ng/g dw in mullet fish from the Tagus estuary. Bivalves, in particular mussels, have shown to be good bioindicator organisms for PhACs and fish for EDCs. Taking into consideration the concentrations and frequencies of detection of PhACs and EDCs in the seafood samples analysed, a list of candidates' compounds for priorization in future studies has been proposed. |
format |
Article in Journal/Newspaper |
author |
Álvarez-Muñoz, D. Rodríguez-Mozaz, S. Maulvault, A.L. Tediosi, A. Fernández-Tejedor, M. Van den Heuvel, F. Kotterman, M. Marques, A. Barceló, D. |
author_facet |
Álvarez-Muñoz, D. Rodríguez-Mozaz, S. Maulvault, A.L. Tediosi, A. Fernández-Tejedor, M. Van den Heuvel, F. Kotterman, M. Marques, A. Barceló, D. |
author_sort |
Álvarez-Muñoz, D. |
title |
Occurrence of pharmaceuticals and endocrine disrupting compounds in macroalgaes, bivalves, and fish from coastal areas in Europe |
title_short |
Occurrence of pharmaceuticals and endocrine disrupting compounds in macroalgaes, bivalves, and fish from coastal areas in Europe |
title_full |
Occurrence of pharmaceuticals and endocrine disrupting compounds in macroalgaes, bivalves, and fish from coastal areas in Europe |
title_fullStr |
Occurrence of pharmaceuticals and endocrine disrupting compounds in macroalgaes, bivalves, and fish from coastal areas in Europe |
title_full_unstemmed |
Occurrence of pharmaceuticals and endocrine disrupting compounds in macroalgaes, bivalves, and fish from coastal areas in Europe |
title_sort |
occurrence of pharmaceuticals and endocrine disrupting compounds in macroalgaes, bivalves, and fish from coastal areas in europe |
publishDate |
2015 |
url |
https://research.wur.nl/en/publications/occurrence-of-pharmaceuticals-and-endocrine-disrupting-compounds- https://doi.org/10.1016/j.envres.2015.09.018 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Crassostrea gigas |
genre_facet |
Crassostrea gigas |
op_source |
Environmental Research 143 (2015) ISSN: 0013-9351 |
op_relation |
info:eu-repo/grantAgreement/EC/FP7/311820 https://edepot.wur.nl/374759 https://research.wur.nl/en/publications/occurrence-of-pharmaceuticals-and-endocrine-disrupting-compounds- doi:10.1016/j.envres.2015.09.018 |
op_rights |
info:eu-repo/semantics/restrictedAccess Wageningen University & Research |
op_doi |
https://doi.org/10.1016/j.envres.2015.09.018 |
container_title |
Environmental Research |
container_volume |
143 |
container_start_page |
56 |
op_container_end_page |
64 |
_version_ |
1788060635825700864 |