Biocatalytic synthesis of new copolymers from 3-hydroxybutyric acid and a carbohydrate lactone
Lipase-catalyzed reaction of 3-hydroxybutyric acid with d-glucono-d-lactone at 5:1 molar ratio and 80 °C yielded a mixture of moderate molecular weight linear and cyclic oligomers. The most efficient biocatalyst, Candida antarctica B lipase (Novozyme 435), allowed the synthesis of new oligomeric com...
Published in: | Journal of Molecular Catalysis B: Enzymatic |
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ftunivwagenin:oai:library.wur.nl:wurpubs/408077 2024-01-14T10:01:32+01:00 Biocatalytic synthesis of new copolymers from 3-hydroxybutyric acid and a carbohydrate lactone Kakasi-Zsurka, S. Todea, A. But, A. Paul, C. Boeriu, C.G. Davidescu, C. Nagy, L. Kuki, A. Keki, S. Peter, F. 2011 application/pdf https://research.wur.nl/en/publications/biocatalytic-synthesis-of-new-copolymers-from-3-hydroxybutyric-ac https://doi.org/10.1016/j.molcatb.2011.03.004 en eng https://edepot.wur.nl/175269 https://research.wur.nl/en/publications/biocatalytic-synthesis-of-new-copolymers-from-3-hydroxybutyric-ac doi:10.1016/j.molcatb.2011.03.004 info:eu-repo/semantics/restrictedAccess Wageningen University & Research Journal of Molecular Catalysis. B, Enzymatic 71 (2011) 1-2 ISSN: 1381-1177 enzymatic-synthesis ionic liquids lipase-catalyzed synthesis polyesters ring-opening polymerization info:eu-repo/semantics/article Article/Letter to editor info:eu-repo/semantics/publishedVersion 2011 ftunivwagenin https://doi.org/10.1016/j.molcatb.2011.03.004 2023-12-20T23:18:54Z Lipase-catalyzed reaction of 3-hydroxybutyric acid with d-glucono-d-lactone at 5:1 molar ratio and 80 °C yielded a mixture of moderate molecular weight linear and cyclic oligomers. The most efficient biocatalyst, Candida antarctica B lipase (Novozyme 435), allowed the synthesis of new oligomeric compounds with ring-opened gluconolactone units included in the oligomeric chain, without previous derivatization of the sugar, or activation of the acid monomer. The reaction medium nature had an important influence on the product composition. Although the main copolymer amount was synthesized in tert-butanol/dimethylsulfoxide medium, the highest polymerization degrees, up to 9 for the copolymer, and 10 for the 3-hydroxybutyric acid homopolymer co-product, were achieved in solventless conditions. Article in Journal/Newspaper Antarc* Antarctica Wageningen UR (University & Research Centre): Digital Library Journal of Molecular Catalysis B: Enzymatic 71 1-2 22 28 |
institution |
Open Polar |
collection |
Wageningen UR (University & Research Centre): Digital Library |
op_collection_id |
ftunivwagenin |
language |
English |
topic |
enzymatic-synthesis ionic liquids lipase-catalyzed synthesis polyesters ring-opening polymerization |
spellingShingle |
enzymatic-synthesis ionic liquids lipase-catalyzed synthesis polyesters ring-opening polymerization Kakasi-Zsurka, S. Todea, A. But, A. Paul, C. Boeriu, C.G. Davidescu, C. Nagy, L. Kuki, A. Keki, S. Peter, F. Biocatalytic synthesis of new copolymers from 3-hydroxybutyric acid and a carbohydrate lactone |
topic_facet |
enzymatic-synthesis ionic liquids lipase-catalyzed synthesis polyesters ring-opening polymerization |
description |
Lipase-catalyzed reaction of 3-hydroxybutyric acid with d-glucono-d-lactone at 5:1 molar ratio and 80 °C yielded a mixture of moderate molecular weight linear and cyclic oligomers. The most efficient biocatalyst, Candida antarctica B lipase (Novozyme 435), allowed the synthesis of new oligomeric compounds with ring-opened gluconolactone units included in the oligomeric chain, without previous derivatization of the sugar, or activation of the acid monomer. The reaction medium nature had an important influence on the product composition. Although the main copolymer amount was synthesized in tert-butanol/dimethylsulfoxide medium, the highest polymerization degrees, up to 9 for the copolymer, and 10 for the 3-hydroxybutyric acid homopolymer co-product, were achieved in solventless conditions. |
format |
Article in Journal/Newspaper |
author |
Kakasi-Zsurka, S. Todea, A. But, A. Paul, C. Boeriu, C.G. Davidescu, C. Nagy, L. Kuki, A. Keki, S. Peter, F. |
author_facet |
Kakasi-Zsurka, S. Todea, A. But, A. Paul, C. Boeriu, C.G. Davidescu, C. Nagy, L. Kuki, A. Keki, S. Peter, F. |
author_sort |
Kakasi-Zsurka, S. |
title |
Biocatalytic synthesis of new copolymers from 3-hydroxybutyric acid and a carbohydrate lactone |
title_short |
Biocatalytic synthesis of new copolymers from 3-hydroxybutyric acid and a carbohydrate lactone |
title_full |
Biocatalytic synthesis of new copolymers from 3-hydroxybutyric acid and a carbohydrate lactone |
title_fullStr |
Biocatalytic synthesis of new copolymers from 3-hydroxybutyric acid and a carbohydrate lactone |
title_full_unstemmed |
Biocatalytic synthesis of new copolymers from 3-hydroxybutyric acid and a carbohydrate lactone |
title_sort |
biocatalytic synthesis of new copolymers from 3-hydroxybutyric acid and a carbohydrate lactone |
publishDate |
2011 |
url |
https://research.wur.nl/en/publications/biocatalytic-synthesis-of-new-copolymers-from-3-hydroxybutyric-ac https://doi.org/10.1016/j.molcatb.2011.03.004 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
Journal of Molecular Catalysis. B, Enzymatic 71 (2011) 1-2 ISSN: 1381-1177 |
op_relation |
https://edepot.wur.nl/175269 https://research.wur.nl/en/publications/biocatalytic-synthesis-of-new-copolymers-from-3-hydroxybutyric-ac doi:10.1016/j.molcatb.2011.03.004 |
op_rights |
info:eu-repo/semantics/restrictedAccess Wageningen University & Research |
op_doi |
https://doi.org/10.1016/j.molcatb.2011.03.004 |
container_title |
Journal of Molecular Catalysis B: Enzymatic |
container_volume |
71 |
container_issue |
1-2 |
container_start_page |
22 |
op_container_end_page |
28 |
_version_ |
1788067298315075584 |