The influence of flumequine and oxytetracycline on the resistance of European eel against the parasitic swimbladder nematode Anguillicola crassus.
The effect of the antibacterial drugs flumequine (FQ) and oxytetracycline (OTC) on the defence system of the European eel (Anguilla anguilla L., 1758) was investigated using an experimentally induced infection with the parasitic swimbladder nematode Anguillicola crassus. Eight weeks after oral admin...
Published in: | Veterinary Immunology and Immunopathology |
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Language: | English |
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1996
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Online Access: | https://research.wur.nl/en/publications/the-influence-of-flumequine-and-oxytetracycline-on-the-resistance https://doi.org/10.1016/0165-2427(95)05532-0 |
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ftunivwagenin:oai:library.wur.nl:wurpubs/36102 2024-02-04T09:52:57+01:00 The influence of flumequine and oxytetracycline on the resistance of European eel against the parasitic swimbladder nematode Anguillicola crassus. van der Heijden, M.H.T. Helders, G.M. Booms, G.H.R. Huisman, E.A. Rombout, J.H.W.M. Boon, J.H. 1996 application/pdf https://research.wur.nl/en/publications/the-influence-of-flumequine-and-oxytetracycline-on-the-resistance https://doi.org/10.1016/0165-2427(95)05532-0 en eng https://edepot.wur.nl/29256 https://research.wur.nl/en/publications/the-influence-of-flumequine-and-oxytetracycline-on-the-resistance doi:10.1016/0165-2427(95)05532-0 info:eu-repo/semantics/restrictedAccess Wageningen University & Research Veterinary Immunology and Immunopathology 52 (1996) ISSN: 0165-2427 Anguillicola crassus European eel antibacterial drugs leucocytes resistance info:eu-repo/semantics/article Article/Letter to editor info:eu-repo/semantics/publishedVersion 1996 ftunivwagenin https://doi.org/10.1016/0165-2427(95)05532-0 2024-01-10T23:29:20Z The effect of the antibacterial drugs flumequine (FQ) and oxytetracycline (OTC) on the defence system of the European eel (Anguilla anguilla L., 1758) was investigated using an experimentally induced infection with the parasitic swimbladder nematode Anguillicola crassus. Eight weeks after oral administration of infective larvae, the mean recovery of the parasites in FQ-treated eels was lower than in non-medicated control animals, and significantly lower than in OTC-treated eels. Mean numbers of peripheral blood granulocytes and B-lymphocytes, as well as the total number of circulating lymphoid cells, showed a significant increase as a result of the infection, while drug treatment merely affected the quantity of the lymphoid cells. The difference in protection against the parasite after FQ or OTC administration points to a modulation of the fish resistance as a result of the drug treatment. The results favour a modulation of the cellular rather than the humoral response, as no specific antibodies were found. Article in Journal/Newspaper Anguilla anguilla Wageningen UR (University & Research Centre): Digital Library Veterinary Immunology and Immunopathology 52 1-2 127 134 |
institution |
Open Polar |
collection |
Wageningen UR (University & Research Centre): Digital Library |
op_collection_id |
ftunivwagenin |
language |
English |
topic |
Anguillicola crassus European eel antibacterial drugs leucocytes resistance |
spellingShingle |
Anguillicola crassus European eel antibacterial drugs leucocytes resistance van der Heijden, M.H.T. Helders, G.M. Booms, G.H.R. Huisman, E.A. Rombout, J.H.W.M. Boon, J.H. The influence of flumequine and oxytetracycline on the resistance of European eel against the parasitic swimbladder nematode Anguillicola crassus. |
topic_facet |
Anguillicola crassus European eel antibacterial drugs leucocytes resistance |
description |
The effect of the antibacterial drugs flumequine (FQ) and oxytetracycline (OTC) on the defence system of the European eel (Anguilla anguilla L., 1758) was investigated using an experimentally induced infection with the parasitic swimbladder nematode Anguillicola crassus. Eight weeks after oral administration of infective larvae, the mean recovery of the parasites in FQ-treated eels was lower than in non-medicated control animals, and significantly lower than in OTC-treated eels. Mean numbers of peripheral blood granulocytes and B-lymphocytes, as well as the total number of circulating lymphoid cells, showed a significant increase as a result of the infection, while drug treatment merely affected the quantity of the lymphoid cells. The difference in protection against the parasite after FQ or OTC administration points to a modulation of the fish resistance as a result of the drug treatment. The results favour a modulation of the cellular rather than the humoral response, as no specific antibodies were found. |
format |
Article in Journal/Newspaper |
author |
van der Heijden, M.H.T. Helders, G.M. Booms, G.H.R. Huisman, E.A. Rombout, J.H.W.M. Boon, J.H. |
author_facet |
van der Heijden, M.H.T. Helders, G.M. Booms, G.H.R. Huisman, E.A. Rombout, J.H.W.M. Boon, J.H. |
author_sort |
van der Heijden, M.H.T. |
title |
The influence of flumequine and oxytetracycline on the resistance of European eel against the parasitic swimbladder nematode Anguillicola crassus. |
title_short |
The influence of flumequine and oxytetracycline on the resistance of European eel against the parasitic swimbladder nematode Anguillicola crassus. |
title_full |
The influence of flumequine and oxytetracycline on the resistance of European eel against the parasitic swimbladder nematode Anguillicola crassus. |
title_fullStr |
The influence of flumequine and oxytetracycline on the resistance of European eel against the parasitic swimbladder nematode Anguillicola crassus. |
title_full_unstemmed |
The influence of flumequine and oxytetracycline on the resistance of European eel against the parasitic swimbladder nematode Anguillicola crassus. |
title_sort |
influence of flumequine and oxytetracycline on the resistance of european eel against the parasitic swimbladder nematode anguillicola crassus. |
publishDate |
1996 |
url |
https://research.wur.nl/en/publications/the-influence-of-flumequine-and-oxytetracycline-on-the-resistance https://doi.org/10.1016/0165-2427(95)05532-0 |
genre |
Anguilla anguilla |
genre_facet |
Anguilla anguilla |
op_source |
Veterinary Immunology and Immunopathology 52 (1996) ISSN: 0165-2427 |
op_relation |
https://edepot.wur.nl/29256 https://research.wur.nl/en/publications/the-influence-of-flumequine-and-oxytetracycline-on-the-resistance doi:10.1016/0165-2427(95)05532-0 |
op_rights |
info:eu-repo/semantics/restrictedAccess Wageningen University & Research |
op_doi |
https://doi.org/10.1016/0165-2427(95)05532-0 |
container_title |
Veterinary Immunology and Immunopathology |
container_volume |
52 |
container_issue |
1-2 |
container_start_page |
127 |
op_container_end_page |
134 |
_version_ |
1789962898159697920 |