Patterns of gene flow define species of thermophilic Archaea
Despite a growing appreciation of their vast diversity in nature, mechanisms of speciation are poorly understood in Bacteria and Archaea. Here we use high-throughput genome sequencing to identify ongoing speciation in the thermoacidophilic Archaeon Sulfolobus islandicus. Patterns of homologous gene...
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ftunivtsydney:oai:opus.lib.uts.edu.au:10453/23572 2023-05-15T16:59:21+02:00 Patterns of gene flow define species of thermophilic Archaea Cadillo-Quiroz, H Didelot, X Held, NL Herrera, A Darling, A Reno, ML Krause, DJ Whitaker, RJ 2012-02-01 application/pdf http://hdl.handle.net/10453/23572 unknown PLoS Biology 10.1371/journal.pbio.1001265 PLoS Biology, 2012, 10 (2) 1544-9173 http://hdl.handle.net/10453/23572 Developmental Biology Sulfolobus Likelihood Functions Genetics Population Ecosystem Phylogeny Species Specificity Base Sequence Phenotype Models Genetic Molecular Sequence Data Russia Genetic Speciation Gene Flow High-Throughput Nucleotide Sequencing Homologous Recombination Journal Article 2012 ftunivtsydney 2022-03-13T13:25:41Z Despite a growing appreciation of their vast diversity in nature, mechanisms of speciation are poorly understood in Bacteria and Archaea. Here we use high-throughput genome sequencing to identify ongoing speciation in the thermoacidophilic Archaeon Sulfolobus islandicus. Patterns of homologous gene flow among genomes of 12 strains from a single hot spring in Kamchatka, Russia, demonstrate higher levels of gene flow within than between two persistent, coexisting groups, demonstrating that these microorganisms fit the biological species concept. Furthermore, rates of gene flow between two species are decreasing over time in a manner consistent with incipient speciation. Unlike other microorganisms investigated, we do not observe a relationship between genetic divergence and frequency of recombination along a chromosome, or other physical mechanisms that would reduce gene flow between lineages. Each species has its own genetic island encoding unique physiological functions and a unique growth phenotype that may be indicative of ecological specialization. Genetic differentiation between these coexisting groups occurs in large genomic "continents," indicating the topology of genomic divergence during speciation is not uniform and is not associated with a single locus under strong diversifying selection. These data support a model where species do not require physical barriers to gene flow but are maintained by ecological differentiation. © 2012 Cadillo-Quiroz et al. Article in Journal/Newspaper Kamchatka University of Technology Sydney: OPUS - Open Publications of UTS Scholars |
institution |
Open Polar |
collection |
University of Technology Sydney: OPUS - Open Publications of UTS Scholars |
op_collection_id |
ftunivtsydney |
language |
unknown |
topic |
Developmental Biology Sulfolobus Likelihood Functions Genetics Population Ecosystem Phylogeny Species Specificity Base Sequence Phenotype Models Genetic Molecular Sequence Data Russia Genetic Speciation Gene Flow High-Throughput Nucleotide Sequencing Homologous Recombination |
spellingShingle |
Developmental Biology Sulfolobus Likelihood Functions Genetics Population Ecosystem Phylogeny Species Specificity Base Sequence Phenotype Models Genetic Molecular Sequence Data Russia Genetic Speciation Gene Flow High-Throughput Nucleotide Sequencing Homologous Recombination Cadillo-Quiroz, H Didelot, X Held, NL Herrera, A Darling, A Reno, ML Krause, DJ Whitaker, RJ Patterns of gene flow define species of thermophilic Archaea |
topic_facet |
Developmental Biology Sulfolobus Likelihood Functions Genetics Population Ecosystem Phylogeny Species Specificity Base Sequence Phenotype Models Genetic Molecular Sequence Data Russia Genetic Speciation Gene Flow High-Throughput Nucleotide Sequencing Homologous Recombination |
description |
Despite a growing appreciation of their vast diversity in nature, mechanisms of speciation are poorly understood in Bacteria and Archaea. Here we use high-throughput genome sequencing to identify ongoing speciation in the thermoacidophilic Archaeon Sulfolobus islandicus. Patterns of homologous gene flow among genomes of 12 strains from a single hot spring in Kamchatka, Russia, demonstrate higher levels of gene flow within than between two persistent, coexisting groups, demonstrating that these microorganisms fit the biological species concept. Furthermore, rates of gene flow between two species are decreasing over time in a manner consistent with incipient speciation. Unlike other microorganisms investigated, we do not observe a relationship between genetic divergence and frequency of recombination along a chromosome, or other physical mechanisms that would reduce gene flow between lineages. Each species has its own genetic island encoding unique physiological functions and a unique growth phenotype that may be indicative of ecological specialization. Genetic differentiation between these coexisting groups occurs in large genomic "continents," indicating the topology of genomic divergence during speciation is not uniform and is not associated with a single locus under strong diversifying selection. These data support a model where species do not require physical barriers to gene flow but are maintained by ecological differentiation. © 2012 Cadillo-Quiroz et al. |
format |
Article in Journal/Newspaper |
author |
Cadillo-Quiroz, H Didelot, X Held, NL Herrera, A Darling, A Reno, ML Krause, DJ Whitaker, RJ |
author_facet |
Cadillo-Quiroz, H Didelot, X Held, NL Herrera, A Darling, A Reno, ML Krause, DJ Whitaker, RJ |
author_sort |
Cadillo-Quiroz, H |
title |
Patterns of gene flow define species of thermophilic Archaea |
title_short |
Patterns of gene flow define species of thermophilic Archaea |
title_full |
Patterns of gene flow define species of thermophilic Archaea |
title_fullStr |
Patterns of gene flow define species of thermophilic Archaea |
title_full_unstemmed |
Patterns of gene flow define species of thermophilic Archaea |
title_sort |
patterns of gene flow define species of thermophilic archaea |
publishDate |
2012 |
url |
http://hdl.handle.net/10453/23572 |
genre |
Kamchatka |
genre_facet |
Kamchatka |
op_relation |
PLoS Biology 10.1371/journal.pbio.1001265 PLoS Biology, 2012, 10 (2) 1544-9173 http://hdl.handle.net/10453/23572 |
_version_ |
1766051594953031680 |