SAV Ag CpG/polyI:C formulated vaccination potentiate protective immune responses in Atlantic salmon - no additive or synergistic effect present when co-injecting a Rhabdovirus G-DNA vaccine

• Main Author: Thim, Hanna Leena
• Format: Master Thesis
• Language: English
• Published: University of Tromsø 2013
• Subjects: VDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920; VDP::Agriculture and fishery disciplines: 900::Fisheries science: 920; BIO-3901; Sav’; Atlantic salmon
• Online Access: https://hdl.handle.net/10037/7109

Vaccines of today rely on adjuvant efficacy to provide a link between innate and adaptive immunity. CpG oligodeoxynucleotides (ODN) and polyinosinic:polycytidylic acid (polyI:C) are both toll-like receptor (TLR) ligands signaling through a combination of pathogen recognition receptors (PRR) and in m...