Cross-sectional associations between prevalent vertebral fracture and pulmonary function. The sixth Tromso Study
Persons with vertebral fracture may have reduced pulmonary function, but this association has not been much studied. The aim of this cross-sectional study was therefore to examine the relationship between vertebral fracture and pulmonary function in a general, elderly population. Vertebral morphomet...
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ftunivtroemsoe:oai:munin.uit.no:10037/5699 2023-05-15T18:33:53+02:00 Cross-sectional associations between prevalent vertebral fracture and pulmonary function. The sixth Tromso Study Morseth, Bente Melbye, Hasse Waterloo, Svanhild Haugnes Thomassen, Marte Renate Risberg, Marijke Jongsma Emaus, Nina 2013 https://hdl.handle.net/10037/5699 https://doi.org/10.1186/1471-2318-13-116 eng eng BioMed Central BMC Geriatrics (2013), vol. 13:116 FRIDAID 1061181 http://dx.doi.org/10.1186/1471-2318-13-116 1471-2318 https://hdl.handle.net/10037/5699 URN:NBN:no-uit_munin_5397 openAccess VDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801 VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801 Journal article Tidsskriftartikkel Peer reviewed 2013 ftunivtroemsoe https://doi.org/10.1186/1471-2318-13-116 2021-06-25T17:53:42Z Persons with vertebral fracture may have reduced pulmonary function, but this association has not been much studied. The aim of this cross-sectional study was therefore to examine the relationship between vertebral fracture and pulmonary function in a general, elderly population. Vertebral morphometry was used for vertebral fracture assessment in 2132 elderly men (n = 892) and women (n = 1240) aged 55 to 87 years in the population-based Tromsø Study 2007–08. Pulmonary function was examined by spirometry. Pulmonary function was expressed as FVC% predicted, FEV1% predicted, and FEV1/FVC% predicted values, adjusted FVC, FEV1, and FEV1/FVC, and obstructive and restrictive ventilatory impairment. Vertebral fracture was classified according to appearance, number, severity, and location of fractures. Associations were analyzed using general linear and logistic models. FVC% predicted and FEV1% predicted values were not associated with vertebral fracture (P > 0.05), whereas FEV1/FVC% predicted ratio was associated with both prevalent fracture, number of fractures, severity of fractures, and fracture site in men (P < 0.05), but not in women. When FVC, FEV1, and FEV1/FVC values were adjusted for multiple covariates, we found no significant association with vertebral fracture. Obstructive and restrictive ventilatory impairment was not associated with prevalent vertebral fracture. In conclusion, this study did not confirm any clinically relevant associations between prevalent vertebral fracture and ventilatory impairment in elderly individuals. Article in Journal/Newspaper Tromso Tromso Tromsø University of Tromsø: Munin Open Research Archive Tromso ENVELOPE(16.546,16.546,68.801,68.801) Tromsø BMC Geriatrics 13 1 |
institution |
Open Polar |
collection |
University of Tromsø: Munin Open Research Archive |
op_collection_id |
ftunivtroemsoe |
language |
English |
topic |
VDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801 VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801 |
spellingShingle |
VDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801 VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801 Morseth, Bente Melbye, Hasse Waterloo, Svanhild Haugnes Thomassen, Marte Renate Risberg, Marijke Jongsma Emaus, Nina Cross-sectional associations between prevalent vertebral fracture and pulmonary function. The sixth Tromso Study |
topic_facet |
VDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801 VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801 |
description |
Persons with vertebral fracture may have reduced pulmonary function, but this association has not been much studied. The aim of this cross-sectional study was therefore to examine the relationship between vertebral fracture and pulmonary function in a general, elderly population. Vertebral morphometry was used for vertebral fracture assessment in 2132 elderly men (n = 892) and women (n = 1240) aged 55 to 87 years in the population-based Tromsø Study 2007–08. Pulmonary function was examined by spirometry. Pulmonary function was expressed as FVC% predicted, FEV1% predicted, and FEV1/FVC% predicted values, adjusted FVC, FEV1, and FEV1/FVC, and obstructive and restrictive ventilatory impairment. Vertebral fracture was classified according to appearance, number, severity, and location of fractures. Associations were analyzed using general linear and logistic models. FVC% predicted and FEV1% predicted values were not associated with vertebral fracture (P > 0.05), whereas FEV1/FVC% predicted ratio was associated with both prevalent fracture, number of fractures, severity of fractures, and fracture site in men (P < 0.05), but not in women. When FVC, FEV1, and FEV1/FVC values were adjusted for multiple covariates, we found no significant association with vertebral fracture. Obstructive and restrictive ventilatory impairment was not associated with prevalent vertebral fracture. In conclusion, this study did not confirm any clinically relevant associations between prevalent vertebral fracture and ventilatory impairment in elderly individuals. |
format |
Article in Journal/Newspaper |
author |
Morseth, Bente Melbye, Hasse Waterloo, Svanhild Haugnes Thomassen, Marte Renate Risberg, Marijke Jongsma Emaus, Nina |
author_facet |
Morseth, Bente Melbye, Hasse Waterloo, Svanhild Haugnes Thomassen, Marte Renate Risberg, Marijke Jongsma Emaus, Nina |
author_sort |
Morseth, Bente |
title |
Cross-sectional associations between prevalent vertebral fracture and pulmonary function. The sixth Tromso Study |
title_short |
Cross-sectional associations between prevalent vertebral fracture and pulmonary function. The sixth Tromso Study |
title_full |
Cross-sectional associations between prevalent vertebral fracture and pulmonary function. The sixth Tromso Study |
title_fullStr |
Cross-sectional associations between prevalent vertebral fracture and pulmonary function. The sixth Tromso Study |
title_full_unstemmed |
Cross-sectional associations between prevalent vertebral fracture and pulmonary function. The sixth Tromso Study |
title_sort |
cross-sectional associations between prevalent vertebral fracture and pulmonary function. the sixth tromso study |
publisher |
BioMed Central |
publishDate |
2013 |
url |
https://hdl.handle.net/10037/5699 https://doi.org/10.1186/1471-2318-13-116 |
long_lat |
ENVELOPE(16.546,16.546,68.801,68.801) |
geographic |
Tromso Tromsø |
geographic_facet |
Tromso Tromsø |
genre |
Tromso Tromso Tromsø |
genre_facet |
Tromso Tromso Tromsø |
op_relation |
BMC Geriatrics (2013), vol. 13:116 FRIDAID 1061181 http://dx.doi.org/10.1186/1471-2318-13-116 1471-2318 https://hdl.handle.net/10037/5699 URN:NBN:no-uit_munin_5397 |
op_rights |
openAccess |
op_doi |
https://doi.org/10.1186/1471-2318-13-116 |
container_title |
BMC Geriatrics |
container_volume |
13 |
container_issue |
1 |
_version_ |
1766218515183828992 |