Cost-effectiveness and quality of life in surgeon versus general practitioner-organised colon cancer surveillance: a randomised controlled trial
The accepted manuscript version of this article is part of Knut Magne Augestad's PhD thesis, which is available in Munin at http://hdl.handle.net/10037/5167 Objective: To assess whether colon cancer follow-up can be organised by general practitioners (GPs) without a decline in the patient'...
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ftunivtroemsoe:oai:munin.uit.no:10037/5641 2023-05-15T17:43:42+02:00 Cost-effectiveness and quality of life in surgeon versus general practitioner-organised colon cancer surveillance: a randomised controlled trial Augestad, Knut Magne Norum, Jan Dehof, Stefan Aspevik, Ranveig Ringberg, Unni Nestvold, Torunn Kristin Vonen, Barthold Skrøvseth, Stein Olav Lindsetmo, Rolv-Ole 2013-04-04 https://hdl.handle.net/10037/5641 https://doi.org/10.1136/bmjopen-2012-002391 eng eng BMJ Open BMJ Open 3(2013) nr. 4 :e002391 FRIDAID 1022754 http://dx.doi.org/10.1136/bmjopen-2012-002391 2044-6055 https://hdl.handle.net/10037/5641 URN:NBN:no-uit_munin_5330 openAccess VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Oncology: 762 VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762 Journal article Tidsskriftartikkel Peer reviewed 2013 ftunivtroemsoe https://doi.org/10.1136/bmjopen-2012-002391 2021-06-25T17:53:35Z The accepted manuscript version of this article is part of Knut Magne Augestad's PhD thesis, which is available in Munin at http://hdl.handle.net/10037/5167 Objective: To assess whether colon cancer follow-up can be organised by general practitioners (GPs) without a decline in the patient's quality of life (QoL) and increase in cost or time to cancer diagnoses, compared to hospital follow-up. Design: Randomised controlled trial. Setting: Northern Norway Health Authority Trust, 4 trusts, 11 hospitals and 88 local communities. Participants: Patients surgically treated for colon cancer, hospital surgeons and community GPs. Intervention: 24-month follow-up according to national guidelines at the community GP office. To ensure a high follow-up guideline adherence, a decision support tool for patients and GPs were used. Main outcome measures: Primary outcomes were QoL, measured by the global health scales of the European Organisation for Research and Treatment of Cancer QoL Questionnaire (EORTC QLQ C-30) and EuroQol-5D (EQ-5D). Secondary outcomes were cost-effectiveness and time to cancer diagnoses. Results: 110 patients were randomised to intervention (n=55) or control (n=55), and followed by 78 GPs (942 follow-up months) and 70 surgeons (942 follow-up months), respectively. Compared to baseline, there was a significant improvement in postoperative QoL (p=0.003), but no differences between groups were revealed (mean difference at 1, 3, 6, 9, 12, 15, 18, 21 and 24-month follow-up appointments): Global Health; Δ−2.23, p=0.20; EQ-5D index; Δ−0.10, p=0.48, EQ-5D VAS; Δ−1.1, p=0.44. There were no differences in time to recurrent cancer diagnosis (GP 35 days vs surgeon 45 days, p=0.46); 14 recurrences were detected (GP 6 vs surgeon 8) and 7 metastases surgeries performed (GP 3 vs surgeon 4). The follow-up programme initiated 1186 healthcare contacts (GP 678 vs surgeon 508), 1105 diagnostic tests (GP 592 vs surgeon 513) and 778 hospital travels (GP 250 vs surgeon 528). GP organised follow-up was associated with societal cost savings (£8233 vs £9889, p<0.001). Conclusions: GP-organised follow-up was associated with no decline in QoL, no increase in time to recurrent cancer diagnosis and cost savings. Article in Journal/Newspaper Northern Norway University of Tromsø: Munin Open Research Archive Norway BMJ Open 3 4 e002391 |
institution |
Open Polar |
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University of Tromsø: Munin Open Research Archive |
op_collection_id |
ftunivtroemsoe |
language |
English |
topic |
VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Oncology: 762 VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762 |
spellingShingle |
VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Oncology: 762 VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762 Augestad, Knut Magne Norum, Jan Dehof, Stefan Aspevik, Ranveig Ringberg, Unni Nestvold, Torunn Kristin Vonen, Barthold Skrøvseth, Stein Olav Lindsetmo, Rolv-Ole Cost-effectiveness and quality of life in surgeon versus general practitioner-organised colon cancer surveillance: a randomised controlled trial |
topic_facet |
VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Oncology: 762 VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762 |
description |
The accepted manuscript version of this article is part of Knut Magne Augestad's PhD thesis, which is available in Munin at http://hdl.handle.net/10037/5167 Objective: To assess whether colon cancer follow-up can be organised by general practitioners (GPs) without a decline in the patient's quality of life (QoL) and increase in cost or time to cancer diagnoses, compared to hospital follow-up. Design: Randomised controlled trial. Setting: Northern Norway Health Authority Trust, 4 trusts, 11 hospitals and 88 local communities. Participants: Patients surgically treated for colon cancer, hospital surgeons and community GPs. Intervention: 24-month follow-up according to national guidelines at the community GP office. To ensure a high follow-up guideline adherence, a decision support tool for patients and GPs were used. Main outcome measures: Primary outcomes were QoL, measured by the global health scales of the European Organisation for Research and Treatment of Cancer QoL Questionnaire (EORTC QLQ C-30) and EuroQol-5D (EQ-5D). Secondary outcomes were cost-effectiveness and time to cancer diagnoses. Results: 110 patients were randomised to intervention (n=55) or control (n=55), and followed by 78 GPs (942 follow-up months) and 70 surgeons (942 follow-up months), respectively. Compared to baseline, there was a significant improvement in postoperative QoL (p=0.003), but no differences between groups were revealed (mean difference at 1, 3, 6, 9, 12, 15, 18, 21 and 24-month follow-up appointments): Global Health; Δ−2.23, p=0.20; EQ-5D index; Δ−0.10, p=0.48, EQ-5D VAS; Δ−1.1, p=0.44. There were no differences in time to recurrent cancer diagnosis (GP 35 days vs surgeon 45 days, p=0.46); 14 recurrences were detected (GP 6 vs surgeon 8) and 7 metastases surgeries performed (GP 3 vs surgeon 4). The follow-up programme initiated 1186 healthcare contacts (GP 678 vs surgeon 508), 1105 diagnostic tests (GP 592 vs surgeon 513) and 778 hospital travels (GP 250 vs surgeon 528). GP organised follow-up was associated with societal cost savings (£8233 vs £9889, p<0.001). Conclusions: GP-organised follow-up was associated with no decline in QoL, no increase in time to recurrent cancer diagnosis and cost savings. |
format |
Article in Journal/Newspaper |
author |
Augestad, Knut Magne Norum, Jan Dehof, Stefan Aspevik, Ranveig Ringberg, Unni Nestvold, Torunn Kristin Vonen, Barthold Skrøvseth, Stein Olav Lindsetmo, Rolv-Ole |
author_facet |
Augestad, Knut Magne Norum, Jan Dehof, Stefan Aspevik, Ranveig Ringberg, Unni Nestvold, Torunn Kristin Vonen, Barthold Skrøvseth, Stein Olav Lindsetmo, Rolv-Ole |
author_sort |
Augestad, Knut Magne |
title |
Cost-effectiveness and quality of life in surgeon versus general practitioner-organised colon cancer surveillance: a randomised controlled trial |
title_short |
Cost-effectiveness and quality of life in surgeon versus general practitioner-organised colon cancer surveillance: a randomised controlled trial |
title_full |
Cost-effectiveness and quality of life in surgeon versus general practitioner-organised colon cancer surveillance: a randomised controlled trial |
title_fullStr |
Cost-effectiveness and quality of life in surgeon versus general practitioner-organised colon cancer surveillance: a randomised controlled trial |
title_full_unstemmed |
Cost-effectiveness and quality of life in surgeon versus general practitioner-organised colon cancer surveillance: a randomised controlled trial |
title_sort |
cost-effectiveness and quality of life in surgeon versus general practitioner-organised colon cancer surveillance: a randomised controlled trial |
publisher |
BMJ Open |
publishDate |
2013 |
url |
https://hdl.handle.net/10037/5641 https://doi.org/10.1136/bmjopen-2012-002391 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Northern Norway |
genre_facet |
Northern Norway |
op_relation |
BMJ Open 3(2013) nr. 4 :e002391 FRIDAID 1022754 http://dx.doi.org/10.1136/bmjopen-2012-002391 2044-6055 https://hdl.handle.net/10037/5641 URN:NBN:no-uit_munin_5330 |
op_rights |
openAccess |
op_doi |
https://doi.org/10.1136/bmjopen-2012-002391 |
container_title |
BMJ Open |
container_volume |
3 |
container_issue |
4 |
container_start_page |
e002391 |
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1766145837728006144 |