Associations between cognitive test scores and pain tolerance: The Tromsø study
The aim of this study is to assess this relationship in a large population-based sample. Methods ‒ We included 5,753 participants (aged 40–84 years) from the seventh wave of the population-based Tromsø Study who had been examined with cognitive tests and experimental pain assessments, and for whom i...
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Online Access: | https://hdl.handle.net/10037/33444 https://doi.org/10.1515/sjpain-2023-0082 |
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ftunivtroemsoe:oai:munin.uit.no:10037/33444 2024-06-02T08:15:19+00:00 Associations between cognitive test scores and pain tolerance: The Tromsø study Melum, Tonje Anita Steingrímsdóttir, Ólöf A. Jacobsen, Henrik B. Johnsen, Bente Stubhaug, Audun Schirmer, Henrik Mathiesen, Ellisiv B. Nielsen, Christopher S. 2024-03-18 https://hdl.handle.net/10037/33444 https://doi.org/10.1515/sjpain-2023-0082 eng eng de Gruyter Scandinavian Journal of Pain Melum, Steingrímsdóttir, Jacobsen, Johnsen, Stubhaug, Schirmer, Mathiesen, Nielsen. Associations between cognitive test scores and pain tolerance: The Tromsø study. Scandinavian Journal of Pain. 2024;24(1):1-10 FRIDAID 2263761 doi:10.1515/sjpain-2023-0082 1877-8860 1877-8879 https://hdl.handle.net/10037/33444 Attribution 4.0 International (CC BY 4.0) openAccess Copyright 2024 The Author(s) https://creativecommons.org/licenses/by/4.0 Journal article Tidsskriftartikkel Peer reviewed publishedVersion 2024 ftunivtroemsoe https://doi.org/10.1515/sjpain-2023-0082 2024-05-07T09:16:20Z The aim of this study is to assess this relationship in a large population-based sample. Methods ‒ We included 5,753 participants (aged 40–84 years) from the seventh wave of the population-based Tromsø Study who had been examined with cognitive tests and experimental pain assessments, and for whom informa tion on covariates were available. Cox regression models were fitted using standardized scores on cognitive tests (12- word immediate recall test, digit symbol coding test, and Mini-Mental State Examination [MMS-E]) as the independent variable and cold pressor or cuff pressure pain tolerance as the dependent variables. Statistical adjustment was made for putative confounders, namely, age, sex, education, smoking, exercise, systolic blood pressure, body mass index, symptoms indicating anxiety or depression, analgesic use, and chronic pain. Results ‒ In multivariate analysis, cold pressor tolerance time was significantly associated with test scores on the 12- word immediate recall test (hazard ratio [HR] 0.93, 95% confidence interval [CI] 0.90–0.97, p < 0.001), the digit symbol coding test (HR 0.94, 95% CI 0.89–0.98, p = 0.004), and the MMS-E (HR 0.93, 95% CI 0.90–0.96 p < 0.001). Tolerance to cuff pressure algometry was significantly associated with 12-word immediate recall (HR 0.94–0.97, p < 0.001) and Digit Symbol Coding test scores (HR 0.93, 95% CI 0.89–0.96, p < 0.001) while there was no significant association with Mini Mental State Examination test score (HR 0.98, 95% CI 0.95–1.00, p = 0.082). Conclusion ‒ Lower pain tolerance was associated with poorer performance on cognitive tests. Article in Journal/Newspaper Tromsø University of Tromsø: Munin Open Research Archive Tromsø Scandinavian Journal of Pain 24 1 |
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Open Polar |
collection |
University of Tromsø: Munin Open Research Archive |
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ftunivtroemsoe |
language |
English |
description |
The aim of this study is to assess this relationship in a large population-based sample. Methods ‒ We included 5,753 participants (aged 40–84 years) from the seventh wave of the population-based Tromsø Study who had been examined with cognitive tests and experimental pain assessments, and for whom informa tion on covariates were available. Cox regression models were fitted using standardized scores on cognitive tests (12- word immediate recall test, digit symbol coding test, and Mini-Mental State Examination [MMS-E]) as the independent variable and cold pressor or cuff pressure pain tolerance as the dependent variables. Statistical adjustment was made for putative confounders, namely, age, sex, education, smoking, exercise, systolic blood pressure, body mass index, symptoms indicating anxiety or depression, analgesic use, and chronic pain. Results ‒ In multivariate analysis, cold pressor tolerance time was significantly associated with test scores on the 12- word immediate recall test (hazard ratio [HR] 0.93, 95% confidence interval [CI] 0.90–0.97, p < 0.001), the digit symbol coding test (HR 0.94, 95% CI 0.89–0.98, p = 0.004), and the MMS-E (HR 0.93, 95% CI 0.90–0.96 p < 0.001). Tolerance to cuff pressure algometry was significantly associated with 12-word immediate recall (HR 0.94–0.97, p < 0.001) and Digit Symbol Coding test scores (HR 0.93, 95% CI 0.89–0.96, p < 0.001) while there was no significant association with Mini Mental State Examination test score (HR 0.98, 95% CI 0.95–1.00, p = 0.082). Conclusion ‒ Lower pain tolerance was associated with poorer performance on cognitive tests. |
format |
Article in Journal/Newspaper |
author |
Melum, Tonje Anita Steingrímsdóttir, Ólöf A. Jacobsen, Henrik B. Johnsen, Bente Stubhaug, Audun Schirmer, Henrik Mathiesen, Ellisiv B. Nielsen, Christopher S. |
spellingShingle |
Melum, Tonje Anita Steingrímsdóttir, Ólöf A. Jacobsen, Henrik B. Johnsen, Bente Stubhaug, Audun Schirmer, Henrik Mathiesen, Ellisiv B. Nielsen, Christopher S. Associations between cognitive test scores and pain tolerance: The Tromsø study |
author_facet |
Melum, Tonje Anita Steingrímsdóttir, Ólöf A. Jacobsen, Henrik B. Johnsen, Bente Stubhaug, Audun Schirmer, Henrik Mathiesen, Ellisiv B. Nielsen, Christopher S. |
author_sort |
Melum, Tonje Anita |
title |
Associations between cognitive test scores and pain tolerance: The Tromsø study |
title_short |
Associations between cognitive test scores and pain tolerance: The Tromsø study |
title_full |
Associations between cognitive test scores and pain tolerance: The Tromsø study |
title_fullStr |
Associations between cognitive test scores and pain tolerance: The Tromsø study |
title_full_unstemmed |
Associations between cognitive test scores and pain tolerance: The Tromsø study |
title_sort |
associations between cognitive test scores and pain tolerance: the tromsø study |
publisher |
de Gruyter |
publishDate |
2024 |
url |
https://hdl.handle.net/10037/33444 https://doi.org/10.1515/sjpain-2023-0082 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
Scandinavian Journal of Pain Melum, Steingrímsdóttir, Jacobsen, Johnsen, Stubhaug, Schirmer, Mathiesen, Nielsen. Associations between cognitive test scores and pain tolerance: The Tromsø study. Scandinavian Journal of Pain. 2024;24(1):1-10 FRIDAID 2263761 doi:10.1515/sjpain-2023-0082 1877-8860 1877-8879 https://hdl.handle.net/10037/33444 |
op_rights |
Attribution 4.0 International (CC BY 4.0) openAccess Copyright 2024 The Author(s) https://creativecommons.org/licenses/by/4.0 |
op_doi |
https://doi.org/10.1515/sjpain-2023-0082 |
container_title |
Scandinavian Journal of Pain |
container_volume |
24 |
container_issue |
1 |
_version_ |
1800739462628507648 |