Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes)
The scavenger endothelial cells (SECs) of vertebrates are an important class of endocytic cells responsible for clearance of foreign and physiological waste macromolecules, partitioning in the immune system, functioning as a cellular powerplant by producing high energy metabolites like lactate and a...
Published in: | Fish & Shellfish Immunology |
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Online Access: | https://hdl.handle.net/10037/32176 https://doi.org/10.1016/j.fsi.2023.109250 |
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ftunivtroemsoe:oai:munin.uit.no:10037/32176 2024-01-14T10:08:33+01:00 Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) Seternes, Tore Poppe, Trygve T Bøgwald, Jarl Lynghammar, Arve Dalmo, Roy Ambli 2023-11-28 https://hdl.handle.net/10037/32176 https://doi.org/10.1016/j.fsi.2023.109250 eng eng Elsevier Fish and Shellfish Immunology Seternes, Poppe, Bøgwald, Lynghammar, Dalmo. Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes). Fish and Shellfish Immunology. 2023 FRIDAID 2213891 doi:10.1016/j.fsi.2023.109250 1050-4648 1095-9947 https://hdl.handle.net/10037/32176 Attribution 4.0 International (CC BY 4.0) openAccess Copyright 2023 The Author(s) https://creativecommons.org/licenses/by/4.0 Journal article Tidsskriftartikkel Peer reviewed publishedVersion 2023 ftunivtroemsoe https://doi.org/10.1016/j.fsi.2023.109250 2023-12-21T00:08:06Z The scavenger endothelial cells (SECs) of vertebrates are an important class of endocytic cells responsible for clearance of foreign and physiological waste macromolecules, partitioning in the immune system, functioning as a cellular powerplant by producing high energy metabolites like lactate and acetate. All animal phyla possess SECs, but the tissue localization of SECs has only been investigated in a limited number of species. By using a specific ligand for scavenger receptors (formalin treated bovine serum albumin), the study revealed that in all tetrapod species (amphibia, reptiles, birds and mammals) the SECs were found lining the sinusoids of the liver. No SECs were found in the liver of any of the bony fishes (Osteichthyes) investigated. Interestingly, we found the SECs not only to be located in the heart of marine species but also in some freshwater species such as Lota lota, Percichthys trucha and Perca fluviatilis. In some fish species, the SECs were found both in the heart and/or kidney in a number of marine and freshwater fishes, whereas in some marine, diadromous and freshwater fishes the SECs were confined only to the kidney tissue. However, from these results it can be suggested that there is neither a clear phylogenetic trend when it came to anatomical localization of SECs nor any pattern in terms of habitat (salinity preferences). Article in Journal/Newspaper Lota lota lota University of Tromsø: Munin Open Research Archive Fish & Shellfish Immunology 144 109250 |
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University of Tromsø: Munin Open Research Archive |
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ftunivtroemsoe |
language |
English |
description |
The scavenger endothelial cells (SECs) of vertebrates are an important class of endocytic cells responsible for clearance of foreign and physiological waste macromolecules, partitioning in the immune system, functioning as a cellular powerplant by producing high energy metabolites like lactate and acetate. All animal phyla possess SECs, but the tissue localization of SECs has only been investigated in a limited number of species. By using a specific ligand for scavenger receptors (formalin treated bovine serum albumin), the study revealed that in all tetrapod species (amphibia, reptiles, birds and mammals) the SECs were found lining the sinusoids of the liver. No SECs were found in the liver of any of the bony fishes (Osteichthyes) investigated. Interestingly, we found the SECs not only to be located in the heart of marine species but also in some freshwater species such as Lota lota, Percichthys trucha and Perca fluviatilis. In some fish species, the SECs were found both in the heart and/or kidney in a number of marine and freshwater fishes, whereas in some marine, diadromous and freshwater fishes the SECs were confined only to the kidney tissue. However, from these results it can be suggested that there is neither a clear phylogenetic trend when it came to anatomical localization of SECs nor any pattern in terms of habitat (salinity preferences). |
format |
Article in Journal/Newspaper |
author |
Seternes, Tore Poppe, Trygve T Bøgwald, Jarl Lynghammar, Arve Dalmo, Roy Ambli |
spellingShingle |
Seternes, Tore Poppe, Trygve T Bøgwald, Jarl Lynghammar, Arve Dalmo, Roy Ambli Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) |
author_facet |
Seternes, Tore Poppe, Trygve T Bøgwald, Jarl Lynghammar, Arve Dalmo, Roy Ambli |
author_sort |
Seternes, Tore |
title |
Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) |
title_short |
Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) |
title_full |
Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) |
title_fullStr |
Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) |
title_full_unstemmed |
Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) |
title_sort |
anatomical distribution of scavenger endothelial cells in bony fishes (osteichthyes) |
publisher |
Elsevier |
publishDate |
2023 |
url |
https://hdl.handle.net/10037/32176 https://doi.org/10.1016/j.fsi.2023.109250 |
genre |
Lota lota lota |
genre_facet |
Lota lota lota |
op_relation |
Fish and Shellfish Immunology Seternes, Poppe, Bøgwald, Lynghammar, Dalmo. Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes). Fish and Shellfish Immunology. 2023 FRIDAID 2213891 doi:10.1016/j.fsi.2023.109250 1050-4648 1095-9947 https://hdl.handle.net/10037/32176 |
op_rights |
Attribution 4.0 International (CC BY 4.0) openAccess Copyright 2023 The Author(s) https://creativecommons.org/licenses/by/4.0 |
op_doi |
https://doi.org/10.1016/j.fsi.2023.109250 |
container_title |
Fish & Shellfish Immunology |
container_volume |
144 |
container_start_page |
109250 |
_version_ |
1788062971752087552 |