Dual-Energy X-Ray Absorptiometry Derived Adiposity Measures and Pre-Frailty/Frailty among Norwegian Adults: The Tromsø Study 2007–2015
OBJECTIVES: Aging is associated with changes in body composition. Excess adiposity among older adults has been linked with metabolic syndromes and aggravated age-associated decline in physical functioning. Few longitudinal studies have explored the association between dual-energy X-ray absorptiometr...
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Online Access: | https://hdl.handle.net/10037/30450 https://doi.org/10.1007/s12603-023-1920-2 |
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ftunivtroemsoe:oai:munin.uit.no:10037/30450 2023-09-26T15:23:48+02:00 Dual-Energy X-Ray Absorptiometry Derived Adiposity Measures and Pre-Frailty/Frailty among Norwegian Adults: The Tromsø Study 2007–2015 Uchai, Shreeshti Andersen, Lene Frost Johansson, Jonas Hopstock, Laila Arnesdatter Hjartåker, Anette 2023-05-25 https://hdl.handle.net/10037/30450 https://doi.org/10.1007/s12603-023-1920-2 eng eng Springer Nature The Journal of Nutrition, Health & Aging Uchai S, Andersen LF, Johansson J, Hopstock LA, Hjartåker A. Dual-Energy X-Ray Absorptiometry Derived Adiposity Measures and Pre-Frailty/Frailty among Norwegian Adults: The Tromsø Study 2007–2015. The Journal of Nutrition, Health & Aging. 2023 FRIDAID 2150272 doi:10.1007/s12603-023-1920-2 1279-7707 1760-4788 https://hdl.handle.net/10037/30450 Attribution 4.0 International (CC BY 4.0) openAccess Copyright 2023 The Author(s) https://creativecommons.org/licenses/by/4.0 Journal article Tidsskriftartikkel Peer reviewed publishedVersion 2023 ftunivtroemsoe https://doi.org/10.1007/s12603-023-1920-2 2023-08-30T23:07:24Z OBJECTIVES: Aging is associated with changes in body composition. Excess adiposity among older adults has been linked with metabolic syndromes and aggravated age-associated decline in physical functioning. Few longitudinal studies have explored the association between dual-energy X-ray absorptiometry (DXA)-derived total as well as central adiposity measures and frailty. We examined the association of DXA-derived total and central adiposity with pre-frailty/ frailty among Norwegian adults after 8 years of follow-up. DESIGN: Prospective observational study. SETTING: Community-dwelling adults from Tromsø, Norway. MEASUREMENTS: Adiposity was defined by fat mass index (FMI) and visceral adipose tissue (VAT) mass assessed using DXA measures. Frailty status was assessed by low grip strength, slow walking speed, exhaustion, unintentional weight loss and low physical activity level. Pre-frail and frail participants at baseline were excluded. Sex-stratified multivariable logistic regression models were used to investigate the association. RESULTS: Participants comprised 234 women (mean age 68 years) and 146 men (mean age 69 years) attending the population-based Tromsø Study in 2007–2008 (Tromsø6) and 2015–2016 (Tromsø7). At the end of follow-up, 25.6% of the women and 27.4% of the men were pre-frail/frail. Compared with women in the lowest tertiles, those in the highest tertile of baseline FMI (odds ratio [OR] 4.42, 95% confidence interval [CI] 1.88–10.35) and VAT mass (OR 2.47, 95% CI 1.10–5.50), respectively had higher odds for pre-frailty/frailty at follow-up. CONCLUSION: We found a higher likelihood of pre-frailty/frailty in later years among women with general and central adiposity in adulthood, highlighting the importance of preventing excess adiposity for healthy aging. Article in Journal/Newspaper Tromsø University of Tromsø: Munin Open Research Archive Norway Tromsø The journal of nutrition, health & aging 27 6 403 410 |
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University of Tromsø: Munin Open Research Archive |
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ftunivtroemsoe |
language |
English |
description |
OBJECTIVES: Aging is associated with changes in body composition. Excess adiposity among older adults has been linked with metabolic syndromes and aggravated age-associated decline in physical functioning. Few longitudinal studies have explored the association between dual-energy X-ray absorptiometry (DXA)-derived total as well as central adiposity measures and frailty. We examined the association of DXA-derived total and central adiposity with pre-frailty/ frailty among Norwegian adults after 8 years of follow-up. DESIGN: Prospective observational study. SETTING: Community-dwelling adults from Tromsø, Norway. MEASUREMENTS: Adiposity was defined by fat mass index (FMI) and visceral adipose tissue (VAT) mass assessed using DXA measures. Frailty status was assessed by low grip strength, slow walking speed, exhaustion, unintentional weight loss and low physical activity level. Pre-frail and frail participants at baseline were excluded. Sex-stratified multivariable logistic regression models were used to investigate the association. RESULTS: Participants comprised 234 women (mean age 68 years) and 146 men (mean age 69 years) attending the population-based Tromsø Study in 2007–2008 (Tromsø6) and 2015–2016 (Tromsø7). At the end of follow-up, 25.6% of the women and 27.4% of the men were pre-frail/frail. Compared with women in the lowest tertiles, those in the highest tertile of baseline FMI (odds ratio [OR] 4.42, 95% confidence interval [CI] 1.88–10.35) and VAT mass (OR 2.47, 95% CI 1.10–5.50), respectively had higher odds for pre-frailty/frailty at follow-up. CONCLUSION: We found a higher likelihood of pre-frailty/frailty in later years among women with general and central adiposity in adulthood, highlighting the importance of preventing excess adiposity for healthy aging. |
format |
Article in Journal/Newspaper |
author |
Uchai, Shreeshti Andersen, Lene Frost Johansson, Jonas Hopstock, Laila Arnesdatter Hjartåker, Anette |
spellingShingle |
Uchai, Shreeshti Andersen, Lene Frost Johansson, Jonas Hopstock, Laila Arnesdatter Hjartåker, Anette Dual-Energy X-Ray Absorptiometry Derived Adiposity Measures and Pre-Frailty/Frailty among Norwegian Adults: The Tromsø Study 2007–2015 |
author_facet |
Uchai, Shreeshti Andersen, Lene Frost Johansson, Jonas Hopstock, Laila Arnesdatter Hjartåker, Anette |
author_sort |
Uchai, Shreeshti |
title |
Dual-Energy X-Ray Absorptiometry Derived Adiposity Measures and Pre-Frailty/Frailty among Norwegian Adults: The Tromsø Study 2007–2015 |
title_short |
Dual-Energy X-Ray Absorptiometry Derived Adiposity Measures and Pre-Frailty/Frailty among Norwegian Adults: The Tromsø Study 2007–2015 |
title_full |
Dual-Energy X-Ray Absorptiometry Derived Adiposity Measures and Pre-Frailty/Frailty among Norwegian Adults: The Tromsø Study 2007–2015 |
title_fullStr |
Dual-Energy X-Ray Absorptiometry Derived Adiposity Measures and Pre-Frailty/Frailty among Norwegian Adults: The Tromsø Study 2007–2015 |
title_full_unstemmed |
Dual-Energy X-Ray Absorptiometry Derived Adiposity Measures and Pre-Frailty/Frailty among Norwegian Adults: The Tromsø Study 2007–2015 |
title_sort |
dual-energy x-ray absorptiometry derived adiposity measures and pre-frailty/frailty among norwegian adults: the tromsø study 2007–2015 |
publisher |
Springer Nature |
publishDate |
2023 |
url |
https://hdl.handle.net/10037/30450 https://doi.org/10.1007/s12603-023-1920-2 |
geographic |
Norway Tromsø |
geographic_facet |
Norway Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
The Journal of Nutrition, Health & Aging Uchai S, Andersen LF, Johansson J, Hopstock LA, Hjartåker A. Dual-Energy X-Ray Absorptiometry Derived Adiposity Measures and Pre-Frailty/Frailty among Norwegian Adults: The Tromsø Study 2007–2015. The Journal of Nutrition, Health & Aging. 2023 FRIDAID 2150272 doi:10.1007/s12603-023-1920-2 1279-7707 1760-4788 https://hdl.handle.net/10037/30450 |
op_rights |
Attribution 4.0 International (CC BY 4.0) openAccess Copyright 2023 The Author(s) https://creativecommons.org/licenses/by/4.0 |
op_doi |
https://doi.org/10.1007/s12603-023-1920-2 |
container_title |
The journal of nutrition, health & aging |
container_volume |
27 |
container_issue |
6 |
container_start_page |
403 |
op_container_end_page |
410 |
_version_ |
1778150116084940800 |