Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate
Background - Left ventricular (LV) systolic and diastolic functions are important cardiovascular risk predictors in patients with hypertension. However, data on segmental, layer-specific strain, and diastolic strain rates in these patients are limited. The aim of this study was to investigate segmen...
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Online Access: | https://hdl.handle.net/10037/30422 https://doi.org/10.1111/echo.15625 |
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ftunivtroemsoe:oai:munin.uit.no:10037/30422 2023-09-26T15:15:35+02:00 Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate Kornev, Mikhail Hatice, Akay Caglayan Kudryavtsev, Alexander V Malyutina, Sofia Ryabikov, Andrew Schirmer, Henrik Rösner, Assami 2023-05-22 https://hdl.handle.net/10037/30422 https://doi.org/10.1111/echo.15625 eng eng Wiley Echocardiography Kornev, Hatice, Kudryavtsev, Malyutina, Ryabikov, Schirmer, Rösner. Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate. Echocardiography. 2023 FRIDAID 2151383 doi:10.1111/echo.15625 0742-2822 1540-8175 https://hdl.handle.net/10037/30422 Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) Copyright 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0 Journal article Tidsskriftartikkel Peer reviewed publishedVersion 2023 ftunivtroemsoe https://doi.org/10.1111/echo.15625 2023-08-30T23:07:26Z Background - Left ventricular (LV) systolic and diastolic functions are important cardiovascular risk predictors in patients with hypertension. However, data on segmental, layer-specific strain, and diastolic strain rates in these patients are limited. The aim of this study was to investigate segmental two-dimensional strain rate imaging (SRI)-derived parameters to characterize LV systolic and diastolic function in hypertensive individuals compared with that in normotensive individuals. Methods - The study sample comprised 1194 participants from the population-based Know Your Heart study in Arkhangelsk and Novosibirsk, Russia, and 1013 individuals from the Seventh Tromsø Study in Norway. The study population was divided into four subgroups: (A) healthy individuals with normal blood pressure (BP), (B) individuals on antihypertensive medication with normal BP, (C) individuals with systolic BP 140–159 mmHg and/or diastolic BP > 90 mm HG, and (D) individuals with systolic BP ≥160 mmHg. In addition to conventional echocardiographic parameters, global and segmental layer-specific strains and strain rates in early diastole and atrial contraction (SR E, SR A) were extracted. The strain and SR (S/SR) analysis included only segments without strain curve artifacts. Results - With increasing BP, the systolic and diastolic global and segmental S/SR gradually decreased. SR E, a marker of impaired relaxation, showed the most distinctive differences between the groups. In normotensive controls and the three hypertension groups, all segmental parameters displayed apico-basal gradients, with the lowest S/SR in the basal septal and highest in apical segments. Only SR A did not differ between the segmental groups but increased gradually with increasing BP. End-systolic strain showed incremental epi-towards endocardial gradients, irrespective of the study group. Conclusion - Arterial hypertension reduces global and segmental systolic and diastolic left ventricular S/SR parameters. Impaired relaxation determined by SR E is the ... Article in Journal/Newspaper Arkhangelsk Tromsø University of Tromsø: Munin Open Research Archive Norway Tromsø Echocardiography 40 7 623 633 |
institution |
Open Polar |
collection |
University of Tromsø: Munin Open Research Archive |
op_collection_id |
ftunivtroemsoe |
language |
English |
description |
Background - Left ventricular (LV) systolic and diastolic functions are important cardiovascular risk predictors in patients with hypertension. However, data on segmental, layer-specific strain, and diastolic strain rates in these patients are limited. The aim of this study was to investigate segmental two-dimensional strain rate imaging (SRI)-derived parameters to characterize LV systolic and diastolic function in hypertensive individuals compared with that in normotensive individuals. Methods - The study sample comprised 1194 participants from the population-based Know Your Heart study in Arkhangelsk and Novosibirsk, Russia, and 1013 individuals from the Seventh Tromsø Study in Norway. The study population was divided into four subgroups: (A) healthy individuals with normal blood pressure (BP), (B) individuals on antihypertensive medication with normal BP, (C) individuals with systolic BP 140–159 mmHg and/or diastolic BP > 90 mm HG, and (D) individuals with systolic BP ≥160 mmHg. In addition to conventional echocardiographic parameters, global and segmental layer-specific strains and strain rates in early diastole and atrial contraction (SR E, SR A) were extracted. The strain and SR (S/SR) analysis included only segments without strain curve artifacts. Results - With increasing BP, the systolic and diastolic global and segmental S/SR gradually decreased. SR E, a marker of impaired relaxation, showed the most distinctive differences between the groups. In normotensive controls and the three hypertension groups, all segmental parameters displayed apico-basal gradients, with the lowest S/SR in the basal septal and highest in apical segments. Only SR A did not differ between the segmental groups but increased gradually with increasing BP. End-systolic strain showed incremental epi-towards endocardial gradients, irrespective of the study group. Conclusion - Arterial hypertension reduces global and segmental systolic and diastolic left ventricular S/SR parameters. Impaired relaxation determined by SR E is the ... |
format |
Article in Journal/Newspaper |
author |
Kornev, Mikhail Hatice, Akay Caglayan Kudryavtsev, Alexander V Malyutina, Sofia Ryabikov, Andrew Schirmer, Henrik Rösner, Assami |
spellingShingle |
Kornev, Mikhail Hatice, Akay Caglayan Kudryavtsev, Alexander V Malyutina, Sofia Ryabikov, Andrew Schirmer, Henrik Rösner, Assami Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
author_facet |
Kornev, Mikhail Hatice, Akay Caglayan Kudryavtsev, Alexander V Malyutina, Sofia Ryabikov, Andrew Schirmer, Henrik Rösner, Assami |
author_sort |
Kornev, Mikhail |
title |
Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
title_short |
Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
title_full |
Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
title_fullStr |
Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
title_full_unstemmed |
Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
title_sort |
influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
publisher |
Wiley |
publishDate |
2023 |
url |
https://hdl.handle.net/10037/30422 https://doi.org/10.1111/echo.15625 |
geographic |
Norway Tromsø |
geographic_facet |
Norway Tromsø |
genre |
Arkhangelsk Tromsø |
genre_facet |
Arkhangelsk Tromsø |
op_relation |
Echocardiography Kornev, Hatice, Kudryavtsev, Malyutina, Ryabikov, Schirmer, Rösner. Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate. Echocardiography. 2023 FRIDAID 2151383 doi:10.1111/echo.15625 0742-2822 1540-8175 https://hdl.handle.net/10037/30422 |
op_rights |
Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) Copyright 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0 |
op_doi |
https://doi.org/10.1111/echo.15625 |
container_title |
Echocardiography |
container_volume |
40 |
container_issue |
7 |
container_start_page |
623 |
op_container_end_page |
633 |
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1778136556269207552 |