Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population
Mortality from cardiovascular diseases (CVDs) is higher in Russia compared to other European countries. High-sensitivity C-reactive protein (hs-CRP) is a biomarker of inflammation, and its elevated levels indicate increased CVD risks. We aim to describe the prevalence of low-grade systemic inflammat...
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ftunivtroemsoe:oai:munin.uit.no:10037/30022 2023-09-05T13:17:53+02:00 Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population Mirolyubova, Olga Kholmatova, Kamila Kahramonzhonovna Postoeva, Anna Kostrova, Galina Malyutina, Sofia Kudryavtsev, Alexander V 2023-05-14 https://hdl.handle.net/10037/30022 https://doi.org/10.3390/biom13050835 eng eng MDPI Biomolecules Mirolyubova, Kholmatova, Postoeva, Kostrova, Malyutina, Kudryavtsev. Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population. Biomolecules. 2023;13(5) FRIDAID 2156516 doi:10.3390/biom13050835 2218-273X https://hdl.handle.net/10037/30022 Attribution 4.0 International (CC BY 4.0) openAccess Copyright 2023 The Author(s) https://creativecommons.org/licenses/by/4.0 Journal article Tidsskriftartikkel Peer reviewed publishedVersion 2023 ftunivtroemsoe https://doi.org/10.3390/biom13050835 2023-08-23T23:07:13Z Mortality from cardiovascular diseases (CVDs) is higher in Russia compared to other European countries. High-sensitivity C-reactive protein (hs-CRP) is a biomarker of inflammation, and its elevated levels indicate increased CVD risks. We aim to describe the prevalence of low-grade systemic inflammation (LGSI) and the associated factors in a Russian population. The Know Your Heart cross-sectional study was conducted in Arkhangelsk, Russia in 2015–2017 with a population sample aged 35–69 years (n = 2380). LGSI was defined as hs-CRP ≥ 2 and <10 mg/L, and its associations with socio-demographic, lifestyle, and cardiometabolic characteristics were analyzed. The prevalence of LGSI (age-standardized to European Standard Population 2013) was 34.1% (33.5% in men and 36.1% in women). In the total sample, the increased odds ratios (ORs) of LGSI were associated with abdominal obesity (2.1), smoking (1.9), dyslipidemia (1.5), pulmonary diseases (1.4), and hypertension (1.3); the decreased ORs were in women (0.6) and in married participants (0.6). In men, the ORs were higher with abdominal obesity (2.1), smoking (2.0), CVDs (1.5), and hazardous drinking (1.5); in women—with abdominal obesity (4.4) and pulmonary diseases (1.5). In conclusion, one-third of the adult population in Arkhangelsk had LGSI. Abdominal obesity was the strongest LGSI correlate in both sexes, while the profiles of other associated factors were different between men and women. Article in Journal/Newspaper Arkhangelsk University of Tromsø: Munin Open Research Archive Biomolecules 13 5 835 |
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University of Tromsø: Munin Open Research Archive |
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ftunivtroemsoe |
language |
English |
description |
Mortality from cardiovascular diseases (CVDs) is higher in Russia compared to other European countries. High-sensitivity C-reactive protein (hs-CRP) is a biomarker of inflammation, and its elevated levels indicate increased CVD risks. We aim to describe the prevalence of low-grade systemic inflammation (LGSI) and the associated factors in a Russian population. The Know Your Heart cross-sectional study was conducted in Arkhangelsk, Russia in 2015–2017 with a population sample aged 35–69 years (n = 2380). LGSI was defined as hs-CRP ≥ 2 and <10 mg/L, and its associations with socio-demographic, lifestyle, and cardiometabolic characteristics were analyzed. The prevalence of LGSI (age-standardized to European Standard Population 2013) was 34.1% (33.5% in men and 36.1% in women). In the total sample, the increased odds ratios (ORs) of LGSI were associated with abdominal obesity (2.1), smoking (1.9), dyslipidemia (1.5), pulmonary diseases (1.4), and hypertension (1.3); the decreased ORs were in women (0.6) and in married participants (0.6). In men, the ORs were higher with abdominal obesity (2.1), smoking (2.0), CVDs (1.5), and hazardous drinking (1.5); in women—with abdominal obesity (4.4) and pulmonary diseases (1.5). In conclusion, one-third of the adult population in Arkhangelsk had LGSI. Abdominal obesity was the strongest LGSI correlate in both sexes, while the profiles of other associated factors were different between men and women. |
format |
Article in Journal/Newspaper |
author |
Mirolyubova, Olga Kholmatova, Kamila Kahramonzhonovna Postoeva, Anna Kostrova, Galina Malyutina, Sofia Kudryavtsev, Alexander V |
spellingShingle |
Mirolyubova, Olga Kholmatova, Kamila Kahramonzhonovna Postoeva, Anna Kostrova, Galina Malyutina, Sofia Kudryavtsev, Alexander V Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population |
author_facet |
Mirolyubova, Olga Kholmatova, Kamila Kahramonzhonovna Postoeva, Anna Kostrova, Galina Malyutina, Sofia Kudryavtsev, Alexander V |
author_sort |
Mirolyubova, Olga |
title |
Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population |
title_short |
Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population |
title_full |
Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population |
title_fullStr |
Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population |
title_full_unstemmed |
Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population |
title_sort |
socio-demographic, lifestyle, and cardiometabolic characteristics associated with low-grade systemic inflammation in russian adult population |
publisher |
MDPI |
publishDate |
2023 |
url |
https://hdl.handle.net/10037/30022 https://doi.org/10.3390/biom13050835 |
genre |
Arkhangelsk |
genre_facet |
Arkhangelsk |
op_relation |
Biomolecules Mirolyubova, Kholmatova, Postoeva, Kostrova, Malyutina, Kudryavtsev. Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population. Biomolecules. 2023;13(5) FRIDAID 2156516 doi:10.3390/biom13050835 2218-273X https://hdl.handle.net/10037/30022 |
op_rights |
Attribution 4.0 International (CC BY 4.0) openAccess Copyright 2023 The Author(s) https://creativecommons.org/licenses/by/4.0 |
op_doi |
https://doi.org/10.3390/biom13050835 |
container_title |
Biomolecules |
container_volume |
13 |
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5 |
container_start_page |
835 |
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1776198891637571584 |