Calanus finmarchicus hydrolysate improves growth performance in feeding trial with European sea bass juveniles and increases skeletal muscle growth in cell studies
The world will be dependent on the development of novel feed ingredients from renewable sources to ensure sustainable growth of the aquaculture industry. Zooplankton like Calanus finmarchicus are viable new raw material candidates, as they have optimal nutrient profiles for aquatic animals and may b...
Published in: | Scientific Reports |
---|---|
Main Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Springer Nature
2023
|
Subjects: | |
Online Access: | https://hdl.handle.net/10037/29964 https://doi.org/10.1038/s41598-023-38970-5 |
id |
ftunivtroemsoe:oai:munin.uit.no:10037/29964 |
---|---|
record_format |
openpolar |
spelling |
ftunivtroemsoe:oai:munin.uit.no:10037/29964 2023-09-05T13:18:13+02:00 Calanus finmarchicus hydrolysate improves growth performance in feeding trial with European sea bass juveniles and increases skeletal muscle growth in cell studies Bøgwald, Isak Østbye, Tone‑Kari K Pedersen, Alice Marie Rønning, Sissel Beate Dias, Jorge Eilertsen, Karl-Erik Wubshet, Sileshi Gizachew 2023-07-29 https://hdl.handle.net/10037/29964 https://doi.org/10.1038/s41598-023-38970-5 eng eng Springer Nature Scientific Reports Nofima AS: 13128 Norges forskningsråd: 312136 Nofima AS: 13411 Norges forskningsråd: 320086 FRIDAID 2166796 https://doi.org/10.1038/s41598-023-38970-5 2045-2322 https://hdl.handle.net/10037/29964 Attribution 4.0 International (CC BY 4.0) openAccess Copyright 2023 The Author(s) https://creativecommons.org/licenses/by/4.0 Journal article Tidsskriftartikkel Peer reviewed publishedVersion 2023 ftunivtroemsoe https://doi.org/10.1038/s41598-023-38970-5 2023-08-23T23:07:13Z The world will be dependent on the development of novel feed ingredients from renewable sources to ensure sustainable growth of the aquaculture industry. Zooplankton like Calanus finmarchicus are viable new raw material candidates, as they have optimal nutrient profiles for aquatic animals and may be sustainably harvested in large volumes. In this study, the aim was to investigate if a protein hydrolysate of C. finmarchicus was able to influence the growth performance of fish. The effect of dietary inclusion of hydrolysates was tested in a feeding trial with European sea bass (Dicentrarchus labrax) juveniles, benchmarking calanus hydrolysate (CH) against commercially available hydrolysates. The diet with CH inclusion yielded increased growth, with significantly higher body weight than hydrolysates of sardine and tuna fish at the end of the trial. The observed growth-promoting effects were further examined using an in vitro model with skeletal muscle cells from Atlantic salmon. Through bioactivity experiments with muscle cells grown in media containing CH, low-molecular fractions were found to have the greatest positive effect on proliferation, viability, and expression of muscle-specific genes. Characterization of the most potent fraction revealed an abundance of small peptides, along with amino acids and marine metabolites associated with increased muscle growth. Article in Journal/Newspaper Atlantic salmon Calanus finmarchicus University of Tromsø: Munin Open Research Archive Scientific Reports 13 1 |
institution |
Open Polar |
collection |
University of Tromsø: Munin Open Research Archive |
op_collection_id |
ftunivtroemsoe |
language |
English |
description |
The world will be dependent on the development of novel feed ingredients from renewable sources to ensure sustainable growth of the aquaculture industry. Zooplankton like Calanus finmarchicus are viable new raw material candidates, as they have optimal nutrient profiles for aquatic animals and may be sustainably harvested in large volumes. In this study, the aim was to investigate if a protein hydrolysate of C. finmarchicus was able to influence the growth performance of fish. The effect of dietary inclusion of hydrolysates was tested in a feeding trial with European sea bass (Dicentrarchus labrax) juveniles, benchmarking calanus hydrolysate (CH) against commercially available hydrolysates. The diet with CH inclusion yielded increased growth, with significantly higher body weight than hydrolysates of sardine and tuna fish at the end of the trial. The observed growth-promoting effects were further examined using an in vitro model with skeletal muscle cells from Atlantic salmon. Through bioactivity experiments with muscle cells grown in media containing CH, low-molecular fractions were found to have the greatest positive effect on proliferation, viability, and expression of muscle-specific genes. Characterization of the most potent fraction revealed an abundance of small peptides, along with amino acids and marine metabolites associated with increased muscle growth. |
format |
Article in Journal/Newspaper |
author |
Bøgwald, Isak Østbye, Tone‑Kari K Pedersen, Alice Marie Rønning, Sissel Beate Dias, Jorge Eilertsen, Karl-Erik Wubshet, Sileshi Gizachew |
spellingShingle |
Bøgwald, Isak Østbye, Tone‑Kari K Pedersen, Alice Marie Rønning, Sissel Beate Dias, Jorge Eilertsen, Karl-Erik Wubshet, Sileshi Gizachew Calanus finmarchicus hydrolysate improves growth performance in feeding trial with European sea bass juveniles and increases skeletal muscle growth in cell studies |
author_facet |
Bøgwald, Isak Østbye, Tone‑Kari K Pedersen, Alice Marie Rønning, Sissel Beate Dias, Jorge Eilertsen, Karl-Erik Wubshet, Sileshi Gizachew |
author_sort |
Bøgwald, Isak |
title |
Calanus finmarchicus hydrolysate improves growth performance in feeding trial with European sea bass juveniles and increases skeletal muscle growth in cell studies |
title_short |
Calanus finmarchicus hydrolysate improves growth performance in feeding trial with European sea bass juveniles and increases skeletal muscle growth in cell studies |
title_full |
Calanus finmarchicus hydrolysate improves growth performance in feeding trial with European sea bass juveniles and increases skeletal muscle growth in cell studies |
title_fullStr |
Calanus finmarchicus hydrolysate improves growth performance in feeding trial with European sea bass juveniles and increases skeletal muscle growth in cell studies |
title_full_unstemmed |
Calanus finmarchicus hydrolysate improves growth performance in feeding trial with European sea bass juveniles and increases skeletal muscle growth in cell studies |
title_sort |
calanus finmarchicus hydrolysate improves growth performance in feeding trial with european sea bass juveniles and increases skeletal muscle growth in cell studies |
publisher |
Springer Nature |
publishDate |
2023 |
url |
https://hdl.handle.net/10037/29964 https://doi.org/10.1038/s41598-023-38970-5 |
genre |
Atlantic salmon Calanus finmarchicus |
genre_facet |
Atlantic salmon Calanus finmarchicus |
op_relation |
Scientific Reports Nofima AS: 13128 Norges forskningsråd: 312136 Nofima AS: 13411 Norges forskningsråd: 320086 FRIDAID 2166796 https://doi.org/10.1038/s41598-023-38970-5 2045-2322 https://hdl.handle.net/10037/29964 |
op_rights |
Attribution 4.0 International (CC BY 4.0) openAccess Copyright 2023 The Author(s) https://creativecommons.org/licenses/by/4.0 |
op_doi |
https://doi.org/10.1038/s41598-023-38970-5 |
container_title |
Scientific Reports |
container_volume |
13 |
container_issue |
1 |
_version_ |
1776199231093080064 |