Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study
Introduction: Cognitive impairment is one of the main disabilities in dementia. Physical activity (PA) has been suggested as protective for dementia. However, the findings are disparate in studies, and the question of whether this is because of reverse causality is still open. We aimed to explore th...
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ftunivtroemsoe:oai:munin.uit.no:10037/26699 2024-04-28T08:40:45+00:00 Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study Johnsen, Bente Strand, Bjørn Heine Martinaityte, Ieva Lorem, Geir Fagerjord Schirmer, Henrik 2022-06-15 https://hdl.handle.net/10037/26699 https://doi.org/10.3389/fnagi.2022.906678 eng eng Frontiers Media Johnsen, B. (2024). Trends for cognitive function and dementia in a general population; Risk factors, trajectories, and incidence. (Doctoral thesis). https://hdl.handle.net/10037/33328 . Frontiers in Aging Neuroscience Johnsen, Strand, Martinaityte, Lorem, Schirmer. Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study. Frontiers in Aging Neuroscience. 2022;14:1-10 FRIDAID 2048916 doi:10.3389/fnagi.2022.906678 1663-4365 https://hdl.handle.net/10037/26699 openAccess Copyright 2022 The Author(s) Journal article Tidsskriftartikkel Peer reviewed publishedVersion 2022 ftunivtroemsoe https://doi.org/10.3389/fnagi.2022.906678 2024-04-09T23:34:20Z Introduction: Cognitive impairment is one of the main disabilities in dementia. Physical activity (PA) has been suggested as protective for dementia. However, the findings are disparate in studies, and the question of whether this is because of reverse causality is still open. We aimed to explore the association of PA with cognition in people who later developed dementia compared to those who did not. Method: Since 2001, 11,512 (55% women) participants over the age of 50 years had taken at least one cognitive test in the Tromsø Study. Of these, 1,123 (58% women) later developed dementia. The cases were extracted from hospital journals and entered into an endpoint registry. Leisure time PA (LTPA) was self-reported. Multilevel mixed-effects linear regression was used to address whether LTPA was associated with cognition, stratified by those later developing dementia, and dementia-free in a separate analysis. Results: Leisure time PA was associated with scores in cognitive tests that were 55% (z-score 0.14) higher in those who did not develop dementia. For those in a preclinical phase of dementia, there was no association with LTPA on global cognitive scores. However, in a multifactorial test on processing speed and memory, women had a positive association with processing speed and memory. Conclusion: Leisure time PA had a positive association with global cognition function only for those who did not develop dementia. In women who were developing dementia, LTPA had a positive association with processing speed and memory, while in men, there were no such associations. Article in Journal/Newspaper Tromsø University of Tromsø: Munin Open Research Archive Frontiers in Aging Neuroscience 14 |
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University of Tromsø: Munin Open Research Archive |
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English |
description |
Introduction: Cognitive impairment is one of the main disabilities in dementia. Physical activity (PA) has been suggested as protective for dementia. However, the findings are disparate in studies, and the question of whether this is because of reverse causality is still open. We aimed to explore the association of PA with cognition in people who later developed dementia compared to those who did not. Method: Since 2001, 11,512 (55% women) participants over the age of 50 years had taken at least one cognitive test in the Tromsø Study. Of these, 1,123 (58% women) later developed dementia. The cases were extracted from hospital journals and entered into an endpoint registry. Leisure time PA (LTPA) was self-reported. Multilevel mixed-effects linear regression was used to address whether LTPA was associated with cognition, stratified by those later developing dementia, and dementia-free in a separate analysis. Results: Leisure time PA was associated with scores in cognitive tests that were 55% (z-score 0.14) higher in those who did not develop dementia. For those in a preclinical phase of dementia, there was no association with LTPA on global cognitive scores. However, in a multifactorial test on processing speed and memory, women had a positive association with processing speed and memory. Conclusion: Leisure time PA had a positive association with global cognition function only for those who did not develop dementia. In women who were developing dementia, LTPA had a positive association with processing speed and memory, while in men, there were no such associations. |
format |
Article in Journal/Newspaper |
author |
Johnsen, Bente Strand, Bjørn Heine Martinaityte, Ieva Lorem, Geir Fagerjord Schirmer, Henrik |
spellingShingle |
Johnsen, Bente Strand, Bjørn Heine Martinaityte, Ieva Lorem, Geir Fagerjord Schirmer, Henrik Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study |
author_facet |
Johnsen, Bente Strand, Bjørn Heine Martinaityte, Ieva Lorem, Geir Fagerjord Schirmer, Henrik |
author_sort |
Johnsen, Bente |
title |
Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study |
title_short |
Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study |
title_full |
Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study |
title_fullStr |
Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study |
title_full_unstemmed |
Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study |
title_sort |
leisure time physical activities’ association with cognition and dementia: a 19 years’ life course study |
publisher |
Frontiers Media |
publishDate |
2022 |
url |
https://hdl.handle.net/10037/26699 https://doi.org/10.3389/fnagi.2022.906678 |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
Johnsen, B. (2024). Trends for cognitive function and dementia in a general population; Risk factors, trajectories, and incidence. (Doctoral thesis). https://hdl.handle.net/10037/33328 . Frontiers in Aging Neuroscience Johnsen, Strand, Martinaityte, Lorem, Schirmer. Leisure Time Physical Activities’ Association With Cognition and Dementia: A 19 Years’ Life Course Study. Frontiers in Aging Neuroscience. 2022;14:1-10 FRIDAID 2048916 doi:10.3389/fnagi.2022.906678 1663-4365 https://hdl.handle.net/10037/26699 |
op_rights |
openAccess Copyright 2022 The Author(s) |
op_doi |
https://doi.org/10.3389/fnagi.2022.906678 |
container_title |
Frontiers in Aging Neuroscience |
container_volume |
14 |
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1797571287786192896 |