Antimicrobial activity and mode of action - Examples from natural products, peptides, and peptidomimetics

Infections caused by bacteria are the third leading cause of death worldwide. Antimicrobials are used to treat and prevent those infections and enabled the development of the modern healthcare system as we know it. However, those achievements are threatened by the global emergence of antimicrobial-r...

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Bibliographic Details
Main Author: Juskewitz, Eric
Format: Doctoral or Postdoctoral Thesis
Language:English
Published: UiT The Arctic University of Norway 2022
Subjects:
AMP
Online Access:https://hdl.handle.net/10037/25912
Description
Summary:Infections caused by bacteria are the third leading cause of death worldwide. Antimicrobials are used to treat and prevent those infections and enabled the development of the modern healthcare system as we know it. However, those achievements are threatened by the global emergence of antimicrobial-resistant bacteria. There is an obvious need for developing new antimicrobials. Natural environments, like the Arctic Ocean, offer largely underexplored biodiversity with promising natural antimicrobial products. This thesis investigates marine and marine-inspired molecules for their antibacterial properties and potential applications.