Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway
Hepatitis E virus (HEV) is a common cause of viral hepatitis in humans. In developing countries, HEV-infections seem to be mainly associated with pigs, but other animal species may be involved in viral transmission. Recently, anti-HEV antibodies were detected in Norwegian wild reindeer. Here, we inv...
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ftunivtroemsoe:oai:munin.uit.no:10037/24087 2023-05-15T18:04:04+02:00 Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway Rinaldo, Christine Hanssen Nymo, Ingebjørg Helena Sanchez Romano, Javier Breines, Eva Marie Murguzur, Francisco Javier Ancin Tryland, Morten 2021-11-25 https://hdl.handle.net/10037/24087 https://doi.org/10.3390/pathogens10121542 eng eng MDPI Pathogens Rinaldo CH, Nymo IH, Sanchez Romano J, Breines EM, Murguzur F, Tryland M. Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway. Pathogens. 2021;10(12):1-12 FRIDAID 1969412 doi:10.3390/pathogens10121542 2076-0817 https://hdl.handle.net/10037/24087 openAccess Copyright 2021 The Author(s) Journal article Tidsskriftartikkel Peer reviewed publishedVersion 2021 ftunivtroemsoe https://doi.org/10.3390/pathogens10121542 2022-02-23T23:58:01Z Hepatitis E virus (HEV) is a common cause of viral hepatitis in humans. In developing countries, HEV-infections seem to be mainly associated with pigs, but other animal species may be involved in viral transmission. Recently, anti-HEV antibodies were detected in Norwegian wild reindeer. Here, we investigated anti-HEV seroprevalence in Norwegian semi-domesticated reindeer, animals in closer contact with humans than their wild counterparts. Blood samples (n = 516) were obtained from eight reindeer herds during the period 2013–2017 and analysed with a commercial enzyme-linked immunosorbent assay designed for detecting anti-HEV antibodies in livestock. Antibodies were found in all herds and for all sampling seasons. The overall seroprevalence was 15.7% (81/516), with adults showing a slightly higher seroprevalence (18.0%, 46/256) than calves (13.5%, 35/260, p = 0.11). The seroprevalence was not influenced by gender or latitude, and there was no temporal trend (p > 0.15). A positive association between the presence of anti-HEV antibodies and antibodies against alphaherpesvirus and pestivirus, detected in a previous screening, was found (p < 0.05). We conclude that Norwegian semi-domesticated reindeer are exposed to HEV or an antigenically similar virus. Whether the virus is affecting reindeer health or infects humans and poses a threat for human health remains unknown and warrants further investigations. Article in Journal/Newspaper Rangifer Rangifer tarandus Tundra University of Tromsø: Munin Open Research Archive Norway Pathogens 10 12 1542 |
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Open Polar |
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University of Tromsø: Munin Open Research Archive |
op_collection_id |
ftunivtroemsoe |
language |
English |
description |
Hepatitis E virus (HEV) is a common cause of viral hepatitis in humans. In developing countries, HEV-infections seem to be mainly associated with pigs, but other animal species may be involved in viral transmission. Recently, anti-HEV antibodies were detected in Norwegian wild reindeer. Here, we investigated anti-HEV seroprevalence in Norwegian semi-domesticated reindeer, animals in closer contact with humans than their wild counterparts. Blood samples (n = 516) were obtained from eight reindeer herds during the period 2013–2017 and analysed with a commercial enzyme-linked immunosorbent assay designed for detecting anti-HEV antibodies in livestock. Antibodies were found in all herds and for all sampling seasons. The overall seroprevalence was 15.7% (81/516), with adults showing a slightly higher seroprevalence (18.0%, 46/256) than calves (13.5%, 35/260, p = 0.11). The seroprevalence was not influenced by gender or latitude, and there was no temporal trend (p > 0.15). A positive association between the presence of anti-HEV antibodies and antibodies against alphaherpesvirus and pestivirus, detected in a previous screening, was found (p < 0.05). We conclude that Norwegian semi-domesticated reindeer are exposed to HEV or an antigenically similar virus. Whether the virus is affecting reindeer health or infects humans and poses a threat for human health remains unknown and warrants further investigations. |
format |
Article in Journal/Newspaper |
author |
Rinaldo, Christine Hanssen Nymo, Ingebjørg Helena Sanchez Romano, Javier Breines, Eva Marie Murguzur, Francisco Javier Ancin Tryland, Morten |
spellingShingle |
Rinaldo, Christine Hanssen Nymo, Ingebjørg Helena Sanchez Romano, Javier Breines, Eva Marie Murguzur, Francisco Javier Ancin Tryland, Morten Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway |
author_facet |
Rinaldo, Christine Hanssen Nymo, Ingebjørg Helena Sanchez Romano, Javier Breines, Eva Marie Murguzur, Francisco Javier Ancin Tryland, Morten |
author_sort |
Rinaldo, Christine Hanssen |
title |
Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway |
title_short |
Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway |
title_full |
Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway |
title_fullStr |
Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway |
title_full_unstemmed |
Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway |
title_sort |
serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (rangifer tarandus tarandus) in norway |
publisher |
MDPI |
publishDate |
2021 |
url |
https://hdl.handle.net/10037/24087 https://doi.org/10.3390/pathogens10121542 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Rangifer Rangifer tarandus Tundra |
genre_facet |
Rangifer Rangifer tarandus Tundra |
op_relation |
Pathogens Rinaldo CH, Nymo IH, Sanchez Romano J, Breines EM, Murguzur F, Tryland M. Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway. Pathogens. 2021;10(12):1-12 FRIDAID 1969412 doi:10.3390/pathogens10121542 2076-0817 https://hdl.handle.net/10037/24087 |
op_rights |
openAccess Copyright 2021 The Author(s) |
op_doi |
https://doi.org/10.3390/pathogens10121542 |
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Pathogens |
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10 |
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12 |
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1542 |
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