Genetic drivers for resistance and susceptibility traits in Atlantic salmon (Salmo salar) towards salmon lice (Lepeophtheirus salmonis)
Salmon lice (Lepeophtheirus salmonis), a common parasite on salmonids is one of the biggest problem the aquaculture industry faces today. The current methods used to combat salmon lice in farmed Atlantic salmon (Salmo salar) industry are often considered to affect the ecosystem negatively; and ineff...
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UiT The Arctic University of Norway
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ftunivtroemsoe:oai:munin.uit.no:10037/22302 2023-05-15T15:30:01+02:00 Genetic drivers for resistance and susceptibility traits in Atlantic salmon (Salmo salar) towards salmon lice (Lepeophtheirus salmonis) James Abraham, Jeff 2021-05-16 https://hdl.handle.net/10037/22302 eng eng UiT The Arctic University of Norway UiT Norges arktiske universitet https://hdl.handle.net/10037/22302 Copyright 2021 The Author(s) VDP::Agriculture and fishery disciplines: 900::Fisheries science: 920::Aquaculture: 922 VDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920::Akvakultur: 922 VDP::Agriculture and fishery disciplines: 900::Fisheries science: 920::Fish health: 923 VDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920::Fiskehelse: 923 Atlantic Salmon salmon lice genetic resistance susceptibility heritability vaccines Salmon genes FSK-3910 Master thesis Mastergradsoppgave 2021 ftunivtroemsoe 2021-09-01T22:53:42Z Salmon lice (Lepeophtheirus salmonis), a common parasite on salmonids is one of the biggest problem the aquaculture industry faces today. The current methods used to combat salmon lice in farmed Atlantic salmon (Salmo salar) industry are often considered to affect the ecosystem negatively; and inefficient in a long run long run due to development of resistance in the parasite. The potential of methods involving epigenetic modification of farmed fish to develop a lice resistant progeny of farmed salmon is not widely explored. A systematic literature review was used to collect and analyse data from peer reviewed scientific articles, science journals and industrial reports. Data were extracted from 55 peer reviewed articles, 2 science journals and 3 industrial reports based on the inclusion criteria. The summary results lice resistance in Atlantic salmon is described to be a polygenic trait. The differential expression of immune related genes have a significant role in variation in resistance and susceptibility of Atlantic salmon towards salmon lice. Vaccines and immune-modulatory in-feed additives could induce differential gene expressions leading to increased lice resistance in salmon. The heritability of lice resistance trait in salmon is moderate to low, but could be improved with epigenetic methods including selective breeding. The epigenetic memory in salmon is reported to be preserved in the form of DNA methylation. Taking this into account, the epigenetic memories of previous lice infection and differential gene expression could be stored fish DNA and potentially inheritable. Further research on epigenetic memory in Atlantic salmon on the perspective of the trait for lice resistance would be a great step towards developing a lice resistant progeny of salmon. However, the impacts of epigenetic modification on farmed salmon and ecosystem have to be considered in further studies. Master Thesis Atlantic salmon Salmo salar University of Tromsø: Munin Open Research Archive |
institution |
Open Polar |
collection |
University of Tromsø: Munin Open Research Archive |
op_collection_id |
ftunivtroemsoe |
language |
English |
topic |
VDP::Agriculture and fishery disciplines: 900::Fisheries science: 920::Aquaculture: 922 VDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920::Akvakultur: 922 VDP::Agriculture and fishery disciplines: 900::Fisheries science: 920::Fish health: 923 VDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920::Fiskehelse: 923 Atlantic Salmon salmon lice genetic resistance susceptibility heritability vaccines Salmon genes FSK-3910 |
spellingShingle |
VDP::Agriculture and fishery disciplines: 900::Fisheries science: 920::Aquaculture: 922 VDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920::Akvakultur: 922 VDP::Agriculture and fishery disciplines: 900::Fisheries science: 920::Fish health: 923 VDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920::Fiskehelse: 923 Atlantic Salmon salmon lice genetic resistance susceptibility heritability vaccines Salmon genes FSK-3910 James Abraham, Jeff Genetic drivers for resistance and susceptibility traits in Atlantic salmon (Salmo salar) towards salmon lice (Lepeophtheirus salmonis) |
topic_facet |
VDP::Agriculture and fishery disciplines: 900::Fisheries science: 920::Aquaculture: 922 VDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920::Akvakultur: 922 VDP::Agriculture and fishery disciplines: 900::Fisheries science: 920::Fish health: 923 VDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920::Fiskehelse: 923 Atlantic Salmon salmon lice genetic resistance susceptibility heritability vaccines Salmon genes FSK-3910 |
description |
Salmon lice (Lepeophtheirus salmonis), a common parasite on salmonids is one of the biggest problem the aquaculture industry faces today. The current methods used to combat salmon lice in farmed Atlantic salmon (Salmo salar) industry are often considered to affect the ecosystem negatively; and inefficient in a long run long run due to development of resistance in the parasite. The potential of methods involving epigenetic modification of farmed fish to develop a lice resistant progeny of farmed salmon is not widely explored. A systematic literature review was used to collect and analyse data from peer reviewed scientific articles, science journals and industrial reports. Data were extracted from 55 peer reviewed articles, 2 science journals and 3 industrial reports based on the inclusion criteria. The summary results lice resistance in Atlantic salmon is described to be a polygenic trait. The differential expression of immune related genes have a significant role in variation in resistance and susceptibility of Atlantic salmon towards salmon lice. Vaccines and immune-modulatory in-feed additives could induce differential gene expressions leading to increased lice resistance in salmon. The heritability of lice resistance trait in salmon is moderate to low, but could be improved with epigenetic methods including selective breeding. The epigenetic memory in salmon is reported to be preserved in the form of DNA methylation. Taking this into account, the epigenetic memories of previous lice infection and differential gene expression could be stored fish DNA and potentially inheritable. Further research on epigenetic memory in Atlantic salmon on the perspective of the trait for lice resistance would be a great step towards developing a lice resistant progeny of salmon. However, the impacts of epigenetic modification on farmed salmon and ecosystem have to be considered in further studies. |
format |
Master Thesis |
author |
James Abraham, Jeff |
author_facet |
James Abraham, Jeff |
author_sort |
James Abraham, Jeff |
title |
Genetic drivers for resistance and susceptibility traits in Atlantic salmon (Salmo salar) towards salmon lice (Lepeophtheirus salmonis) |
title_short |
Genetic drivers for resistance and susceptibility traits in Atlantic salmon (Salmo salar) towards salmon lice (Lepeophtheirus salmonis) |
title_full |
Genetic drivers for resistance and susceptibility traits in Atlantic salmon (Salmo salar) towards salmon lice (Lepeophtheirus salmonis) |
title_fullStr |
Genetic drivers for resistance and susceptibility traits in Atlantic salmon (Salmo salar) towards salmon lice (Lepeophtheirus salmonis) |
title_full_unstemmed |
Genetic drivers for resistance and susceptibility traits in Atlantic salmon (Salmo salar) towards salmon lice (Lepeophtheirus salmonis) |
title_sort |
genetic drivers for resistance and susceptibility traits in atlantic salmon (salmo salar) towards salmon lice (lepeophtheirus salmonis) |
publisher |
UiT The Arctic University of Norway |
publishDate |
2021 |
url |
https://hdl.handle.net/10037/22302 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_relation |
https://hdl.handle.net/10037/22302 |
op_rights |
Copyright 2021 The Author(s) |
_version_ |
1766360467985399808 |