Ancient origin and genetic segregation of canine circovirus infecting arctic foxes (Vulpes lagopus) in Svalbard and red foxes (Vulpes vulpes) in Northern Norway
This is the pre-peer reviewed version of the following article: Urbani, Tryland, Ehrich, Fuglei, Battilani, Balboni. Ancient origin and genetic segregation of canine circovirus infecting arctic foxes (Vulpes lagopus) in Svalbard and red foxes (Vulpes vulpes) in Northern Norway. Transboundary and Eme...
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Online Access: | https://hdl.handle.net/10037/20615 https://doi.org/10.1111/tbed.13783 |
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ftunivtroemsoe:oai:munin.uit.no:10037/20615 2023-05-15T14:26:08+02:00 Ancient origin and genetic segregation of canine circovirus infecting arctic foxes (Vulpes lagopus) in Svalbard and red foxes (Vulpes vulpes) in Northern Norway Urbani, Lorenza Tryland, Morten Ehrich, Dorothee Fuglei, Eva Battilani, Mara Balboni, Andrea 2020-08-12 https://hdl.handle.net/10037/20615 https://doi.org/10.1111/tbed.13783 eng eng Wiley Transboundary and Emerging Diseases Urbani, Tryland, Ehrich, Fuglei, Battilani, Balboni. Ancient origin and genetic segregation of canine circovirus infecting arctic foxes (Vulpes lagopus) in Svalbard and red foxes (Vulpes vulpes) in Northern Norway. Transboundary and Emerging Diseases. 2020;00:1-11 FRIDAID 1843560 doi:10.1111/tbed.13783 1865-1674 1865-1682 https://hdl.handle.net/10037/20615 embargoedAccess Copyright 2020 The Author(s) VDP::Mathematics and natural science: 400::Zoology and botany: 480 VDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480 Journal article Tidsskriftartikkel Peer reviewed acceptedVersion 2020 ftunivtroemsoe https://doi.org/10.1111/tbed.13783 2021-06-25T17:58:05Z This is the pre-peer reviewed version of the following article: Urbani, Tryland, Ehrich, Fuglei, Battilani, Balboni. Ancient origin and genetic segregation of canine circovirus infecting arctic foxes (Vulpes lagopus) in Svalbard and red foxes (Vulpes vulpes) in Northern Norway. Transboundary and Emerging Diseases. 2020;00:1-11, which has been published in final form at https://doi.org/10.1111/tbed.13783. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Canine circovirus (CanineCV) is a relatively new viral species, belonging to the family Circoviridae , whose pathogenic role is still uncertain. Since its first description in one domestic dog in 2011 from the USA, several reports have been documenting its distribution worldwide. Recently, CanineCV was also detected in wild animals such as wolves, foxes and badgers. In order to investigate the presence and the genetic characteristics of CanineCV in foxes of Arctic and Sub‐Arctic regions, the presence of CanineCV DNA in internal organs (liver and spleen) of 51 arctic foxes ( Vulpes lagopus ) from Svalbard archipelago and 59 red foxes ( Vulpes vulpes ) from Northern Norway, sampled from 1996 to 2001 and from 2014 to 2018, respectively, was screened by real‐time PCR. CanineCV was detected in 11/51 arctic foxes and in 10/59 red foxes, backdating the circulation of the virus at least to 1996 in the arctic fox population. The complete genome of 14 identified CanineCV was sequenced and analysed showing an identity higher than 80.8% with the reference strains available to date. According to the species demarcation threshold of 80% genome‐wide nucleotide sequence identity for members of the family Circoviridae provided by International Committee on Taxonomy of Viruses (ICTV), all the CanineCV belong to a single species. Phylogenetic analysis revealed that all the CanineCV were subdivided into five main clusters with one including only CanineCV identified in foxes. Furthermore, CanineCV identified in arctic foxes and red foxes formed two distinct lineages. From these data, we hypothesize that the viral transmission did not occur between the two species of foxes as a consequence of the lack of contact between the two hosts or that the virus acquired mutations in the time elapsed between the samplings. Article in Journal/Newspaper Arctic Arctic Fox Arctic Northern Norway Svalbard Vulpes lagopus University of Tromsø: Munin Open Research Archive Arctic Norway Svalbard Svalbard Archipelago Transboundary and Emerging Diseases 68 3 1283 1293 |
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Open Polar |
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University of Tromsø: Munin Open Research Archive |
op_collection_id |
ftunivtroemsoe |
language |
English |
topic |
VDP::Mathematics and natural science: 400::Zoology and botany: 480 VDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480 |
spellingShingle |
VDP::Mathematics and natural science: 400::Zoology and botany: 480 VDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480 Urbani, Lorenza Tryland, Morten Ehrich, Dorothee Fuglei, Eva Battilani, Mara Balboni, Andrea Ancient origin and genetic segregation of canine circovirus infecting arctic foxes (Vulpes lagopus) in Svalbard and red foxes (Vulpes vulpes) in Northern Norway |
topic_facet |
VDP::Mathematics and natural science: 400::Zoology and botany: 480 VDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480 |
description |
This is the pre-peer reviewed version of the following article: Urbani, Tryland, Ehrich, Fuglei, Battilani, Balboni. Ancient origin and genetic segregation of canine circovirus infecting arctic foxes (Vulpes lagopus) in Svalbard and red foxes (Vulpes vulpes) in Northern Norway. Transboundary and Emerging Diseases. 2020;00:1-11, which has been published in final form at https://doi.org/10.1111/tbed.13783. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Canine circovirus (CanineCV) is a relatively new viral species, belonging to the family Circoviridae , whose pathogenic role is still uncertain. Since its first description in one domestic dog in 2011 from the USA, several reports have been documenting its distribution worldwide. Recently, CanineCV was also detected in wild animals such as wolves, foxes and badgers. In order to investigate the presence and the genetic characteristics of CanineCV in foxes of Arctic and Sub‐Arctic regions, the presence of CanineCV DNA in internal organs (liver and spleen) of 51 arctic foxes ( Vulpes lagopus ) from Svalbard archipelago and 59 red foxes ( Vulpes vulpes ) from Northern Norway, sampled from 1996 to 2001 and from 2014 to 2018, respectively, was screened by real‐time PCR. CanineCV was detected in 11/51 arctic foxes and in 10/59 red foxes, backdating the circulation of the virus at least to 1996 in the arctic fox population. The complete genome of 14 identified CanineCV was sequenced and analysed showing an identity higher than 80.8% with the reference strains available to date. According to the species demarcation threshold of 80% genome‐wide nucleotide sequence identity for members of the family Circoviridae provided by International Committee on Taxonomy of Viruses (ICTV), all the CanineCV belong to a single species. Phylogenetic analysis revealed that all the CanineCV were subdivided into five main clusters with one including only CanineCV identified in foxes. Furthermore, CanineCV identified in arctic foxes and red foxes formed two distinct lineages. From these data, we hypothesize that the viral transmission did not occur between the two species of foxes as a consequence of the lack of contact between the two hosts or that the virus acquired mutations in the time elapsed between the samplings. |
format |
Article in Journal/Newspaper |
author |
Urbani, Lorenza Tryland, Morten Ehrich, Dorothee Fuglei, Eva Battilani, Mara Balboni, Andrea |
author_facet |
Urbani, Lorenza Tryland, Morten Ehrich, Dorothee Fuglei, Eva Battilani, Mara Balboni, Andrea |
author_sort |
Urbani, Lorenza |
title |
Ancient origin and genetic segregation of canine circovirus infecting arctic foxes (Vulpes lagopus) in Svalbard and red foxes (Vulpes vulpes) in Northern Norway |
title_short |
Ancient origin and genetic segregation of canine circovirus infecting arctic foxes (Vulpes lagopus) in Svalbard and red foxes (Vulpes vulpes) in Northern Norway |
title_full |
Ancient origin and genetic segregation of canine circovirus infecting arctic foxes (Vulpes lagopus) in Svalbard and red foxes (Vulpes vulpes) in Northern Norway |
title_fullStr |
Ancient origin and genetic segregation of canine circovirus infecting arctic foxes (Vulpes lagopus) in Svalbard and red foxes (Vulpes vulpes) in Northern Norway |
title_full_unstemmed |
Ancient origin and genetic segregation of canine circovirus infecting arctic foxes (Vulpes lagopus) in Svalbard and red foxes (Vulpes vulpes) in Northern Norway |
title_sort |
ancient origin and genetic segregation of canine circovirus infecting arctic foxes (vulpes lagopus) in svalbard and red foxes (vulpes vulpes) in northern norway |
publisher |
Wiley |
publishDate |
2020 |
url |
https://hdl.handle.net/10037/20615 https://doi.org/10.1111/tbed.13783 |
geographic |
Arctic Norway Svalbard Svalbard Archipelago |
geographic_facet |
Arctic Norway Svalbard Svalbard Archipelago |
genre |
Arctic Arctic Fox Arctic Northern Norway Svalbard Vulpes lagopus |
genre_facet |
Arctic Arctic Fox Arctic Northern Norway Svalbard Vulpes lagopus |
op_relation |
Transboundary and Emerging Diseases Urbani, Tryland, Ehrich, Fuglei, Battilani, Balboni. Ancient origin and genetic segregation of canine circovirus infecting arctic foxes (Vulpes lagopus) in Svalbard and red foxes (Vulpes vulpes) in Northern Norway. Transboundary and Emerging Diseases. 2020;00:1-11 FRIDAID 1843560 doi:10.1111/tbed.13783 1865-1674 1865-1682 https://hdl.handle.net/10037/20615 |
op_rights |
embargoedAccess Copyright 2020 The Author(s) |
op_doi |
https://doi.org/10.1111/tbed.13783 |
container_title |
Transboundary and Emerging Diseases |
container_volume |
68 |
container_issue |
3 |
container_start_page |
1283 |
op_container_end_page |
1293 |
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1766298617153323008 |