An incomplete Circle of Willis is not a risk factor for white matter hyperintensities: The Tromsø Study

• Published in: Journal of the Neurological Sciences
• Main Authors: Hindenes, Lars Bakke, Håberg, Asta Kristine, Mathiesen, Ellisiv B, Vangberg, Torgil Riise
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier 2020
• Subjects: VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Neurology: 752; VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Nevrologi: 752; The Tromsø Study; Tromsøundersøkelsen; Tromsø; Willis
• Online Access: https://hdl.handle.net/10037/20500; https://doi.org/10.1016/j.jns.2020.117268

Objective - The Circle of Willis (CoW) is often underdeveloped or incomplete, leading to suboptimal blood supply to the brain. As hypoperfusion is thought to play a role in the aetiology of white matter hyperintensities (WMH), the objective of this study was to assess whether incomplete CoW variants...