The Marine Natural Product Mimic MHP88 Shows Anticancer Activity and has the Potential to Cause Immunogenic Cell Death

• Main Authors: von Hofsten, Susannah, Norvoll Magnussen, Synnøve, Ausbacher, Dominik, Paulsen, Marianne Hagensen, Bayer, Annette, Strøm, Morten B., Berge, Gerd
• Format: Conference Object
• Language: English
• Published: 2020
• Subjects: VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Oncology: 762; VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762; Arctic; Ramos
• Online Access: https://hdl.handle.net/10037/19579

Conference web site at https://www.eaa2020.org/ . The marine natural product mimic MHP 88 is a novel synthetic molecule based on unique structures found in molecules from an arctic marine bryozoan. Initial studies showed that MHP88 kills cancer cells efficiently, but is not hemolytic. In this study,...