Oxidant-induced modifications in the mucosal transcriptome and circulating metabolome of Atlantic salmon

• Published in: Aquatic Toxicology
• Main Authors: Lazado, Carlo C., Pedersen, Lars-Flemming, Kirste, Katrine H., Soleng, Malene, Breiland, Mette Serine Wesmajervi, Timmerhaus, Gerrit
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier 2020
• Subjects: VDP::Agriculture and fishery disciplines: 900::Fisheries science: 920; VDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920; Paa; Atlantic salmon; Salmo salar
• Online Access: https://hdl.handle.net/10037/19433; https://doi.org/10.1016/j.aquatox.2020.105625

Here we report the molecular networks associated with the mucosal and systemic responses to peracetic acid (PAA), a candidate oxidative chemotherapeutic in Atlantic salmon ( Salmo salar ). Smolts were exposed to different therapeutic doses (0, 0.6 and 2.4 mg/L) of PAA for 5 min, followed by a re-exp...