Pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: Comparison between population-based studies in Russia and Norway
Background - Cardiovascular disease (CVD) mortality is substantially higher in Russia than in neighbouring Norway. We aimed to compare blood pressure- and lipid-lowering medication use and proportion meeting treatment targets between general population samples in the two countries in those with CVD...
Published in: | BMC Cardiovascular Disorders |
---|---|
Main Authors: | , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
BMC
2020
|
Subjects: | |
Online Access: | https://hdl.handle.net/10037/18562 https://doi.org/10.1186/s12872-020-01513-1 |
id |
ftunivtroemsoe:oai:munin.uit.no:10037/18562 |
---|---|
record_format |
openpolar |
spelling |
ftunivtroemsoe:oai:munin.uit.no:10037/18562 2023-05-15T18:34:18+02:00 Pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: Comparison between population-based studies in Russia and Norway Cook, Sarah Anne Hopstock, Laila Arnesdatter Eggen, Anne Elise Bates, Katie Iakunchykova, Olena Kontsevaya, Anna McKee, Martin Schirmer, Henrik Voevoda, Michael Kudryavtsev, Alexander V Malyutina, Sofia Leon, David A. 2020-05-19 https://hdl.handle.net/10037/18562 https://doi.org/10.1186/s12872-020-01513-1 eng eng BMC BMC Cardiovascular Disorders Cook SA, Hopstock LA, Eggen AE, Bates K, Iakunchykova O, Kontsevaya A, McKee M, Schirmer H, Voevoda, Kudryavtsev AV, Malyutina S, Leon DA. Pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: Comparison between population-based studies in Russia and Norway. BMC Cardiovascular Disorders. 2020;20(234) FRIDAID 1812135 https://doi.org/10.1186/s12872-020-01513-1 1471-2261 https://hdl.handle.net/10037/18562 openAccess Copyright 2020 The Author(s) VDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801 VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801 Journal article Tidsskriftartikkel Peer reviewed publishedVersion 2020 ftunivtroemsoe https://doi.org/10.1186/s12872-020-01513-1 2021-06-25T17:57:29Z Background - Cardiovascular disease (CVD) mortality is substantially higher in Russia than in neighbouring Norway. We aimed to compare blood pressure- and lipid-lowering medication use and proportion meeting treatment targets between general population samples in the two countries in those with CVD and diabetes. Methods - The study population was adults aged 40–69 years reporting a diagnosis of myocardial infarction (MI), stroke and/or diabetes participating in cross-sectional population-based studies in Russia (Know Your Heart (KYH) 2015–18 N = 626) and Norway (The Tromsø Study 2015–16 (Tromsø 7) N = 1353). Reported medications were coded according to the 2016 WHO Anatomical Therapeutic Chemical Classification system. Treatment targets were defined using the Joint European Societies guidelines for CVD prevention in clinical practice (2016). Results - Age- and sex-standardized prevalence of use of lipid-lowering medications was higher in Tromsø 7 for all three conditions with a disproportionately large difference in those reporting MI (+ 48% (95% CI 39, 57%)). Proportion meeting treatment targets for LDL cholesterol was poor in both studies (age- and sex-standardized prevalence of control KYH vs Tromsø 7: MI 5.1% vs 10.1%; stroke 11.6% vs 5.8%; diabetes 24.9% vs 23.3%). Use of antihypertensive medication was higher in KYH for stroke (+ 40% (95% CI 30, 50%)) and diabetes (+ 27% (95% CI 19, 34%)) groups but approximately equal for the MI group (− 1% (95% CI -1, 1%)). Proportion meeting blood pressure targets was lower in KYH vs Tromsø 7 (MI 51.8% vs 76.3%; stroke 49.5% vs 69.6%; diabetes 51.9% vs 63.9%). Conclusions - We identified different patterns of medication use in people with CVD and diabetes. However despite higher use of lipid-lowering medication in the Norwegian study treatment to target for total cholesterol was poor in both Russian and Norwegian studies. In contrast we found higher levels of use of antihypertensive medications in the Russian study but also that less participants met treatment targets for blood pressure. Further work should investigate what factors are responsible for this seeming paradox and how management of modifiable risk factors for secondary prevention could be improved. Article in Journal/Newspaper Tromsø University of Tromsø: Munin Open Research Archive Norway Tromsø BMC Cardiovascular Disorders 20 1 |
institution |
Open Polar |
collection |
University of Tromsø: Munin Open Research Archive |
op_collection_id |
ftunivtroemsoe |
language |
English |
topic |
VDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801 VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801 |
spellingShingle |
VDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801 VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801 Cook, Sarah Anne Hopstock, Laila Arnesdatter Eggen, Anne Elise Bates, Katie Iakunchykova, Olena Kontsevaya, Anna McKee, Martin Schirmer, Henrik Voevoda, Michael Kudryavtsev, Alexander V Malyutina, Sofia Leon, David A. Pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: Comparison between population-based studies in Russia and Norway |
topic_facet |
VDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801 VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801 |
description |
Background - Cardiovascular disease (CVD) mortality is substantially higher in Russia than in neighbouring Norway. We aimed to compare blood pressure- and lipid-lowering medication use and proportion meeting treatment targets between general population samples in the two countries in those with CVD and diabetes. Methods - The study population was adults aged 40–69 years reporting a diagnosis of myocardial infarction (MI), stroke and/or diabetes participating in cross-sectional population-based studies in Russia (Know Your Heart (KYH) 2015–18 N = 626) and Norway (The Tromsø Study 2015–16 (Tromsø 7) N = 1353). Reported medications were coded according to the 2016 WHO Anatomical Therapeutic Chemical Classification system. Treatment targets were defined using the Joint European Societies guidelines for CVD prevention in clinical practice (2016). Results - Age- and sex-standardized prevalence of use of lipid-lowering medications was higher in Tromsø 7 for all three conditions with a disproportionately large difference in those reporting MI (+ 48% (95% CI 39, 57%)). Proportion meeting treatment targets for LDL cholesterol was poor in both studies (age- and sex-standardized prevalence of control KYH vs Tromsø 7: MI 5.1% vs 10.1%; stroke 11.6% vs 5.8%; diabetes 24.9% vs 23.3%). Use of antihypertensive medication was higher in KYH for stroke (+ 40% (95% CI 30, 50%)) and diabetes (+ 27% (95% CI 19, 34%)) groups but approximately equal for the MI group (− 1% (95% CI -1, 1%)). Proportion meeting blood pressure targets was lower in KYH vs Tromsø 7 (MI 51.8% vs 76.3%; stroke 49.5% vs 69.6%; diabetes 51.9% vs 63.9%). Conclusions - We identified different patterns of medication use in people with CVD and diabetes. However despite higher use of lipid-lowering medication in the Norwegian study treatment to target for total cholesterol was poor in both Russian and Norwegian studies. In contrast we found higher levels of use of antihypertensive medications in the Russian study but also that less participants met treatment targets for blood pressure. Further work should investigate what factors are responsible for this seeming paradox and how management of modifiable risk factors for secondary prevention could be improved. |
format |
Article in Journal/Newspaper |
author |
Cook, Sarah Anne Hopstock, Laila Arnesdatter Eggen, Anne Elise Bates, Katie Iakunchykova, Olena Kontsevaya, Anna McKee, Martin Schirmer, Henrik Voevoda, Michael Kudryavtsev, Alexander V Malyutina, Sofia Leon, David A. |
author_facet |
Cook, Sarah Anne Hopstock, Laila Arnesdatter Eggen, Anne Elise Bates, Katie Iakunchykova, Olena Kontsevaya, Anna McKee, Martin Schirmer, Henrik Voevoda, Michael Kudryavtsev, Alexander V Malyutina, Sofia Leon, David A. |
author_sort |
Cook, Sarah Anne |
title |
Pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: Comparison between population-based studies in Russia and Norway |
title_short |
Pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: Comparison between population-based studies in Russia and Norway |
title_full |
Pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: Comparison between population-based studies in Russia and Norway |
title_fullStr |
Pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: Comparison between population-based studies in Russia and Norway |
title_full_unstemmed |
Pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: Comparison between population-based studies in Russia and Norway |
title_sort |
pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: comparison between population-based studies in russia and norway |
publisher |
BMC |
publishDate |
2020 |
url |
https://hdl.handle.net/10037/18562 https://doi.org/10.1186/s12872-020-01513-1 |
geographic |
Norway Tromsø |
geographic_facet |
Norway Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
BMC Cardiovascular Disorders Cook SA, Hopstock LA, Eggen AE, Bates K, Iakunchykova O, Kontsevaya A, McKee M, Schirmer H, Voevoda, Kudryavtsev AV, Malyutina S, Leon DA. Pharmacological management of modifiable cardiovascular risk factors (blood pressure and lipids) following diagnosis of myocardial infarction, stroke and diabetes: Comparison between population-based studies in Russia and Norway. BMC Cardiovascular Disorders. 2020;20(234) FRIDAID 1812135 https://doi.org/10.1186/s12872-020-01513-1 1471-2261 https://hdl.handle.net/10037/18562 |
op_rights |
openAccess Copyright 2020 The Author(s) |
op_doi |
https://doi.org/10.1186/s12872-020-01513-1 |
container_title |
BMC Cardiovascular Disorders |
container_volume |
20 |
container_issue |
1 |
_version_ |
1766218984207679488 |