Unique genetic features of canine adenovirus type 1 (CAdV-1) infecting red foxes (Vulpes vulpes) in northern Norway and arctic foxes (Vulpes lagopus) in Svalbard
This is a post-peer-review, pre-copyedit version of an article published in Veterinary Research Communications. The final authenticated version is available online at: https://doi.org/10.1007/s11259-019-09746-y Canine adenovirus type 1 (CAdV-1) is the aetiological agent of infectious canine hepatiti...
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Online Access: | https://hdl.handle.net/10037/17305 https://doi.org/10.1007/s11259-019-09746-y |
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ftunivtroemsoe:oai:munin.uit.no:10037/17305 2023-05-15T14:26:46+02:00 Unique genetic features of canine adenovirus type 1 (CAdV-1) infecting red foxes (Vulpes vulpes) in northern Norway and arctic foxes (Vulpes lagopus) in Svalbard Balboni, Andrea Tryland, Morten Mørk, Torill Killengreen, Siw Turid Fuglei, Eva Battilani, Mara 2019-03-02 https://hdl.handle.net/10037/17305 https://doi.org/10.1007/s11259-019-09746-y eng eng Springer Verlag Veterinary research communications Balboni A, Tryland M, Mørk T, Killengreen St, Fuglei E, Battilani. Unique genetic features of canine adenovirus type 1 (CAdV-1) infecting red foxes (Vulpes vulpes) in northern Norway and arctic foxes (Vulpes lagopus) in Svalbard. Veterinary research communications. 2019;43(2):67-76 FRIDAID 1708112 doi:10.1007/s11259-019-09746-y 0165-7380 1573-7446 https://hdl.handle.net/10037/17305 openAccess © Springer Nature B.V. 2019 VDP::Mathematics and natural science: 400::Zoology and botany: 480 VDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480 Journal article Tidsskriftartikkel Peer reviewed acceptedVersion 2019 ftunivtroemsoe https://doi.org/10.1007/s11259-019-09746-y 2021-06-25T17:57:11Z This is a post-peer-review, pre-copyedit version of an article published in Veterinary Research Communications. The final authenticated version is available online at: https://doi.org/10.1007/s11259-019-09746-y Canine adenovirus type 1 (CAdV-1) is the aetiological agent of infectious canine hepatitis (ICH) in domestic dogs ( Canis familiaris ). In spite of the widespread use of vaccination, CAdV-1 continues to circulate in the dog population. Although a high number of serological screenings have indicated that CAdV-1 is widespread in fox species, little is known about the potential role of foxes as reservoirs of CAdV-1. Furthermore, very little data exist on the molecular features of this virus in foxes. To add to existing knowledge on CAdV-1 circulating in wild carnivores, tissue samples from CAdV-seropositive red foxes ( Vulpes vulpes, n = 10) from the northern mainland of Norway and arctic foxes ( Vulpes lagopus, n = 10) from the Svalbard archipelago, Norway, were investigated using a molecular approach to detect CAdV-1 DNA and important structural and non-structural genes of the detected viruses were sequenced and analysed. Amplicons characteristic for CAdV-1 were amplified from 14 out of 20 foxes (7 red foxes and 7 arctic foxes) and spleen and lymph node tissues resulted optimal targets for the viral DNA detection. The nucleotide sequences showed unique features that distinguished the viruses detected in this study from the CAdV-1 to date identified in wild carnivores and dogs. Greater attention should be given to genetically different CAdV-1 circulating in wild carnivores that may be transferred to dogs, potentially causing disease and reducing the effectiveness of available vaccines. Article in Journal/Newspaper Arctic Arctic Northern Norway Svalbard Vulpes lagopus University of Tromsø: Munin Open Research Archive Arctic Norway Svalbard Svalbard Archipelago Veterinary Research Communications 43 2 67 76 |
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University of Tromsø: Munin Open Research Archive |
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language |
English |
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VDP::Mathematics and natural science: 400::Zoology and botany: 480 VDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480 |
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VDP::Mathematics and natural science: 400::Zoology and botany: 480 VDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480 Balboni, Andrea Tryland, Morten Mørk, Torill Killengreen, Siw Turid Fuglei, Eva Battilani, Mara Unique genetic features of canine adenovirus type 1 (CAdV-1) infecting red foxes (Vulpes vulpes) in northern Norway and arctic foxes (Vulpes lagopus) in Svalbard |
topic_facet |
VDP::Mathematics and natural science: 400::Zoology and botany: 480 VDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480 |
description |
This is a post-peer-review, pre-copyedit version of an article published in Veterinary Research Communications. The final authenticated version is available online at: https://doi.org/10.1007/s11259-019-09746-y Canine adenovirus type 1 (CAdV-1) is the aetiological agent of infectious canine hepatitis (ICH) in domestic dogs ( Canis familiaris ). In spite of the widespread use of vaccination, CAdV-1 continues to circulate in the dog population. Although a high number of serological screenings have indicated that CAdV-1 is widespread in fox species, little is known about the potential role of foxes as reservoirs of CAdV-1. Furthermore, very little data exist on the molecular features of this virus in foxes. To add to existing knowledge on CAdV-1 circulating in wild carnivores, tissue samples from CAdV-seropositive red foxes ( Vulpes vulpes, n = 10) from the northern mainland of Norway and arctic foxes ( Vulpes lagopus, n = 10) from the Svalbard archipelago, Norway, were investigated using a molecular approach to detect CAdV-1 DNA and important structural and non-structural genes of the detected viruses were sequenced and analysed. Amplicons characteristic for CAdV-1 were amplified from 14 out of 20 foxes (7 red foxes and 7 arctic foxes) and spleen and lymph node tissues resulted optimal targets for the viral DNA detection. The nucleotide sequences showed unique features that distinguished the viruses detected in this study from the CAdV-1 to date identified in wild carnivores and dogs. Greater attention should be given to genetically different CAdV-1 circulating in wild carnivores that may be transferred to dogs, potentially causing disease and reducing the effectiveness of available vaccines. |
format |
Article in Journal/Newspaper |
author |
Balboni, Andrea Tryland, Morten Mørk, Torill Killengreen, Siw Turid Fuglei, Eva Battilani, Mara |
author_facet |
Balboni, Andrea Tryland, Morten Mørk, Torill Killengreen, Siw Turid Fuglei, Eva Battilani, Mara |
author_sort |
Balboni, Andrea |
title |
Unique genetic features of canine adenovirus type 1 (CAdV-1) infecting red foxes (Vulpes vulpes) in northern Norway and arctic foxes (Vulpes lagopus) in Svalbard |
title_short |
Unique genetic features of canine adenovirus type 1 (CAdV-1) infecting red foxes (Vulpes vulpes) in northern Norway and arctic foxes (Vulpes lagopus) in Svalbard |
title_full |
Unique genetic features of canine adenovirus type 1 (CAdV-1) infecting red foxes (Vulpes vulpes) in northern Norway and arctic foxes (Vulpes lagopus) in Svalbard |
title_fullStr |
Unique genetic features of canine adenovirus type 1 (CAdV-1) infecting red foxes (Vulpes vulpes) in northern Norway and arctic foxes (Vulpes lagopus) in Svalbard |
title_full_unstemmed |
Unique genetic features of canine adenovirus type 1 (CAdV-1) infecting red foxes (Vulpes vulpes) in northern Norway and arctic foxes (Vulpes lagopus) in Svalbard |
title_sort |
unique genetic features of canine adenovirus type 1 (cadv-1) infecting red foxes (vulpes vulpes) in northern norway and arctic foxes (vulpes lagopus) in svalbard |
publisher |
Springer Verlag |
publishDate |
2019 |
url |
https://hdl.handle.net/10037/17305 https://doi.org/10.1007/s11259-019-09746-y |
geographic |
Arctic Norway Svalbard Svalbard Archipelago |
geographic_facet |
Arctic Norway Svalbard Svalbard Archipelago |
genre |
Arctic Arctic Northern Norway Svalbard Vulpes lagopus |
genre_facet |
Arctic Arctic Northern Norway Svalbard Vulpes lagopus |
op_relation |
Veterinary research communications Balboni A, Tryland M, Mørk T, Killengreen St, Fuglei E, Battilani. Unique genetic features of canine adenovirus type 1 (CAdV-1) infecting red foxes (Vulpes vulpes) in northern Norway and arctic foxes (Vulpes lagopus) in Svalbard. Veterinary research communications. 2019;43(2):67-76 FRIDAID 1708112 doi:10.1007/s11259-019-09746-y 0165-7380 1573-7446 https://hdl.handle.net/10037/17305 |
op_rights |
openAccess © Springer Nature B.V. 2019 |
op_doi |
https://doi.org/10.1007/s11259-019-09746-y |
container_title |
Veterinary Research Communications |
container_volume |
43 |
container_issue |
2 |
container_start_page |
67 |
op_container_end_page |
76 |
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1766300192213041152 |