Analysis of the Atlantic salmon genome reveals a cluster of Mx genes that respond more strongly to IFN gamma than to type I IFN

• Published in: Developmental & Comparative Immunology
• Main Authors: Robertsen, Børre, Greiner-Tollersrud, Linn, Jørgensen, Lars Gaute
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier 2018
• Subjects: VDP::Agriculture and fishery disciplines: 900::Fisheries science: 920; VDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920; Gar’; Atlantic salmon
• Online Access: https://hdl.handle.net/10037/17285; https://doi.org/10.1016/j.dci.2018.09.004

Accepted manuscript version, licensed CC BY-NC-ND 4.0. Mx proteins are antiviral GTPases, which are induced by type I IFN and virus infection. Analysis of the Atlantic salmon genome revealed the presence of 9 Mx genes localized to three chromosomes. A cluster of three Mx genes (SsaMx1 – SsaMx3), whi...