Body weight and body mass index influence bone mineral density in late adolescence in a two-year follow-up study. The Tromsø Study: Fit Futures
Determinants of bone acquisition in late adolescence and early adulthood are not well‐described. This 2‐year follow‐up study explored the associations of body weight (BW), body mass index (BMI), and changes in weight status with adolescent bone accretion in a sample of 651 adolescents (355 girls and...
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Online Access: | https://hdl.handle.net/10037/16852 https://doi.org/10.1002/jbm4.10195 |
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ftunivtroemsoe:oai:munin.uit.no:10037/16852 2023-05-15T18:34:31+02:00 Body weight and body mass index influence bone mineral density in late adolescence in a two-year follow-up study. The Tromsø Study: Fit Futures Nilsen, Ole Andreas Ahmed, Luai A. Winther, Anne Christoffersen, Tore Thrane, Gyrd Evensen, Elin Furberg, Anne-Sofie Grimnes, Guri Dennison, Elaine Emaus, Nina 2019-04-04 https://hdl.handle.net/10037/16852 https://doi.org/10.1002/jbm4.10195 eng eng Wiley Nilsen, O.A. (2021). The influence of lifestyle on peak bone mass in Norwegian boys and girls between 15-19 years of age. The Tromsø study, Fit Futures. (Doctoral thesis). https://hdl.handle.net/10037/21150 . JBMR Plus FRIDAID 1691346 doi:10.1002/jbm4.10195 2473-4039 https://hdl.handle.net/10037/16852 openAccess VDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801 VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801 Journal article Tidsskriftartikkel Peer reviewed publishedVersion 2019 ftunivtroemsoe https://doi.org/10.1002/jbm4.10195 2021-06-25T17:56:59Z Determinants of bone acquisition in late adolescence and early adulthood are not well‐described. This 2‐year follow‐up study explored the associations of body weight (BW), body mass index (BMI), and changes in weight status with adolescent bone accretion in a sample of 651 adolescents (355 girls and 296 boys) between 15 and 19 years of age from The Tromsø Study: Fit Futures. This Norwegian population‐based cohort study was conducted from 2010 to 2011 and was repeated from 2012 to 2013. We measured femoral neck, total hip, and total body bone mineral content and areal bone mineral density (aBMD) by dual‐energy X‐ray absorptiometry. We measured height, BW, calculated BMI (kg/m 2 ), and collected information on lifestyle at both surveys. Mean BMI (SD) at baseline was 22.17 (3.76) and 22.18 (3.93) in girls and boys, respectively. Through multiple linear regression, baseline BW and BMI were positively associated with ∆aBMD over 2 years of follow‐up at all skeletal sites in boys ( p < 0.05), but not in girls. ∆BW and ∆BMI predicted ∆aBMD and ∆BMC in both sexes, but the strength of the associations was moderate. Individuals who lost weight during follow‐up demonstrated a slowed progression of aBMD accretion compared with those gaining weight, but loss of BW or reduction of BMI during 2 years was not associated with net loss of aBMD. In conclusion, our results confirm that adequate BW for height in late adolescence is important for bone health. Associations between change in weight status and bone accretion during follow‐up were moderate and unlikely to have any clinical implication on adolescents of normal weight. Underweight individuals, particularly boys, are at risk of not reaching optimal peak bone mass and could benefit from an increase in BMI. Article in Journal/Newspaper Tromsø University of Tromsø: Munin Open Research Archive Tromsø JBMR Plus 3 9 |
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Open Polar |
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University of Tromsø: Munin Open Research Archive |
op_collection_id |
ftunivtroemsoe |
language |
English |
topic |
VDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801 VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801 |
spellingShingle |
VDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801 VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801 Nilsen, Ole Andreas Ahmed, Luai A. Winther, Anne Christoffersen, Tore Thrane, Gyrd Evensen, Elin Furberg, Anne-Sofie Grimnes, Guri Dennison, Elaine Emaus, Nina Body weight and body mass index influence bone mineral density in late adolescence in a two-year follow-up study. The Tromsø Study: Fit Futures |
topic_facet |
VDP::Medical disciplines: 700::Health sciences: 800::Community medicine Social medicine: 801 VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801 |
description |
Determinants of bone acquisition in late adolescence and early adulthood are not well‐described. This 2‐year follow‐up study explored the associations of body weight (BW), body mass index (BMI), and changes in weight status with adolescent bone accretion in a sample of 651 adolescents (355 girls and 296 boys) between 15 and 19 years of age from The Tromsø Study: Fit Futures. This Norwegian population‐based cohort study was conducted from 2010 to 2011 and was repeated from 2012 to 2013. We measured femoral neck, total hip, and total body bone mineral content and areal bone mineral density (aBMD) by dual‐energy X‐ray absorptiometry. We measured height, BW, calculated BMI (kg/m 2 ), and collected information on lifestyle at both surveys. Mean BMI (SD) at baseline was 22.17 (3.76) and 22.18 (3.93) in girls and boys, respectively. Through multiple linear regression, baseline BW and BMI were positively associated with ∆aBMD over 2 years of follow‐up at all skeletal sites in boys ( p < 0.05), but not in girls. ∆BW and ∆BMI predicted ∆aBMD and ∆BMC in both sexes, but the strength of the associations was moderate. Individuals who lost weight during follow‐up demonstrated a slowed progression of aBMD accretion compared with those gaining weight, but loss of BW or reduction of BMI during 2 years was not associated with net loss of aBMD. In conclusion, our results confirm that adequate BW for height in late adolescence is important for bone health. Associations between change in weight status and bone accretion during follow‐up were moderate and unlikely to have any clinical implication on adolescents of normal weight. Underweight individuals, particularly boys, are at risk of not reaching optimal peak bone mass and could benefit from an increase in BMI. |
format |
Article in Journal/Newspaper |
author |
Nilsen, Ole Andreas Ahmed, Luai A. Winther, Anne Christoffersen, Tore Thrane, Gyrd Evensen, Elin Furberg, Anne-Sofie Grimnes, Guri Dennison, Elaine Emaus, Nina |
author_facet |
Nilsen, Ole Andreas Ahmed, Luai A. Winther, Anne Christoffersen, Tore Thrane, Gyrd Evensen, Elin Furberg, Anne-Sofie Grimnes, Guri Dennison, Elaine Emaus, Nina |
author_sort |
Nilsen, Ole Andreas |
title |
Body weight and body mass index influence bone mineral density in late adolescence in a two-year follow-up study. The Tromsø Study: Fit Futures |
title_short |
Body weight and body mass index influence bone mineral density in late adolescence in a two-year follow-up study. The Tromsø Study: Fit Futures |
title_full |
Body weight and body mass index influence bone mineral density in late adolescence in a two-year follow-up study. The Tromsø Study: Fit Futures |
title_fullStr |
Body weight and body mass index influence bone mineral density in late adolescence in a two-year follow-up study. The Tromsø Study: Fit Futures |
title_full_unstemmed |
Body weight and body mass index influence bone mineral density in late adolescence in a two-year follow-up study. The Tromsø Study: Fit Futures |
title_sort |
body weight and body mass index influence bone mineral density in late adolescence in a two-year follow-up study. the tromsø study: fit futures |
publisher |
Wiley |
publishDate |
2019 |
url |
https://hdl.handle.net/10037/16852 https://doi.org/10.1002/jbm4.10195 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
Nilsen, O.A. (2021). The influence of lifestyle on peak bone mass in Norwegian boys and girls between 15-19 years of age. The Tromsø study, Fit Futures. (Doctoral thesis). https://hdl.handle.net/10037/21150 . JBMR Plus FRIDAID 1691346 doi:10.1002/jbm4.10195 2473-4039 https://hdl.handle.net/10037/16852 |
op_rights |
openAccess |
op_doi |
https://doi.org/10.1002/jbm4.10195 |
container_title |
JBMR Plus |
container_volume |
3 |
container_issue |
9 |
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1766219304014970880 |