A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults
Introduction : Vertebral fractures are common osteoporotic fractures, affecting 2–46% of the population, causing morbidity and increased risk of mortality. Physical activity has beneficial effects for bone health, including increased bone mineral density and reduced hip fractures. However, evidence...
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ftunivtroemsoe:oai:munin.uit.no:10037/16846 2023-05-15T18:35:02+02:00 A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults Mikkilä, Saija Calogiuri, Giovanna Emaus, Nina Morseth, Bente 2019-09-17 https://hdl.handle.net/10037/16846 https://doi.org/10.1186/s12891-019-2821-8 eng eng BMC BMC Musculoskeletal Disorders Mikkilä, Calogiuri, Emaus, Morseth. A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults. BMC Musculoskeletal Disorders. 2019;20(435) FRIDAID 1726979 doi:10.1186/s12891-019-2821-8 1471-2474 https://hdl.handle.net/10037/16846 openAccess VDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710 VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710 Journal article Tidsskriftartikkel Peer reviewed publishedVersion 2019 ftunivtroemsoe https://doi.org/10.1186/s12891-019-2821-8 2021-06-25T17:56:59Z Introduction : Vertebral fractures are common osteoporotic fractures, affecting 2–46% of the population, causing morbidity and increased risk of mortality. Physical activity has beneficial effects for bone health, including increased bone mineral density and reduced hip fractures. However, evidence concerning prevention of vertebral fractures is scarce. Therefore, the aim of this study was to investigate the association between leisure time physical activity and vertebral fracture risk. Methods : The data were retrieved from the 2001 and 2007–2008 surveys of the Tromsø Study, a longitudinal population study in Norway. A total of 1904 participants (1030 women and 874 men, age 38–87 yr and 40–87 yr respectively) were included in the cross-sectional analysis (2007–2008). Prospective follow-up data (2001 to 2007) on physical activity were available for 1131 participants (636 women and 495 men, age 32–69 yr and 33–69 yr respectively). Physical activity was assessed by a questionnaire and vertebral fracture by lateral vertebral fracture assessment from dual-energy x-ray absorptiometry scans. Logistic regression was used to examine associations between physical activity and vertebral fracture. Results : After controlling for confounders (age, height, weight, smoking, osteoporosis, osteoporosis medication, left hip total bone mineral density, and use of hormones in women only), no cross-sectional associations between physical activity levels and vertebral fracture were observed, OR 1.13 (95% CI: 0.59–2.13), for moderately active women and 1.44 (0.61–3.42) for highly active women, compared with sedentary women. In men, the respective ORs were 1.74 (95% CI: 0.91–3.35) and 1.64 (0.78–3.41). In the prospective analyses, OR for vertebral fracture in women with reduced physical activity was 0.81 (95% CI: 0.18–3.62), 1.24 (95% CI: 0.29–5.26) for increased physical activity and 1.54 (95% CI: 0.43–5.50) for active unchanged physical activity pattern, compared with sedentary unchanged physical activity. In men, the respective ORs were 2.05 (95% CI: 0.57–7.42), 2.23 (95% CI: 0.63–7.87), and 1.81 (95% CI: 0.54–6.02). Subanalyses of women and men ≥50 yr showed similar results. Conclusions : Our findings suggest that physical activity does not play a major role in preventing vertebral fractures in Norwegian adults. Future studies may benefit from data on incident vertebral fracture, and objectively measured physical activity. Article in Journal/Newspaper Tromsø University of Tromsø: Munin Open Research Archive Norway Tromsø BMC Musculoskeletal Disorders 20 1 |
institution |
Open Polar |
collection |
University of Tromsø: Munin Open Research Archive |
op_collection_id |
ftunivtroemsoe |
language |
English |
topic |
VDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710 VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710 |
spellingShingle |
VDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710 VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710 Mikkilä, Saija Calogiuri, Giovanna Emaus, Nina Morseth, Bente A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
topic_facet |
VDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710 VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710 |
description |
Introduction : Vertebral fractures are common osteoporotic fractures, affecting 2–46% of the population, causing morbidity and increased risk of mortality. Physical activity has beneficial effects for bone health, including increased bone mineral density and reduced hip fractures. However, evidence concerning prevention of vertebral fractures is scarce. Therefore, the aim of this study was to investigate the association between leisure time physical activity and vertebral fracture risk. Methods : The data were retrieved from the 2001 and 2007–2008 surveys of the Tromsø Study, a longitudinal population study in Norway. A total of 1904 participants (1030 women and 874 men, age 38–87 yr and 40–87 yr respectively) were included in the cross-sectional analysis (2007–2008). Prospective follow-up data (2001 to 2007) on physical activity were available for 1131 participants (636 women and 495 men, age 32–69 yr and 33–69 yr respectively). Physical activity was assessed by a questionnaire and vertebral fracture by lateral vertebral fracture assessment from dual-energy x-ray absorptiometry scans. Logistic regression was used to examine associations between physical activity and vertebral fracture. Results : After controlling for confounders (age, height, weight, smoking, osteoporosis, osteoporosis medication, left hip total bone mineral density, and use of hormones in women only), no cross-sectional associations between physical activity levels and vertebral fracture were observed, OR 1.13 (95% CI: 0.59–2.13), for moderately active women and 1.44 (0.61–3.42) for highly active women, compared with sedentary women. In men, the respective ORs were 1.74 (95% CI: 0.91–3.35) and 1.64 (0.78–3.41). In the prospective analyses, OR for vertebral fracture in women with reduced physical activity was 0.81 (95% CI: 0.18–3.62), 1.24 (95% CI: 0.29–5.26) for increased physical activity and 1.54 (95% CI: 0.43–5.50) for active unchanged physical activity pattern, compared with sedentary unchanged physical activity. In men, the respective ORs were 2.05 (95% CI: 0.57–7.42), 2.23 (95% CI: 0.63–7.87), and 1.81 (95% CI: 0.54–6.02). Subanalyses of women and men ≥50 yr showed similar results. Conclusions : Our findings suggest that physical activity does not play a major role in preventing vertebral fractures in Norwegian adults. Future studies may benefit from data on incident vertebral fracture, and objectively measured physical activity. |
format |
Article in Journal/Newspaper |
author |
Mikkilä, Saija Calogiuri, Giovanna Emaus, Nina Morseth, Bente |
author_facet |
Mikkilä, Saija Calogiuri, Giovanna Emaus, Nina Morseth, Bente |
author_sort |
Mikkilä, Saija |
title |
A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
title_short |
A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
title_full |
A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
title_fullStr |
A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
title_full_unstemmed |
A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
title_sort |
cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
publisher |
BMC |
publishDate |
2019 |
url |
https://hdl.handle.net/10037/16846 https://doi.org/10.1186/s12891-019-2821-8 |
geographic |
Norway Tromsø |
geographic_facet |
Norway Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
BMC Musculoskeletal Disorders Mikkilä, Calogiuri, Emaus, Morseth. A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults. BMC Musculoskeletal Disorders. 2019;20(435) FRIDAID 1726979 doi:10.1186/s12891-019-2821-8 1471-2474 https://hdl.handle.net/10037/16846 |
op_rights |
openAccess |
op_doi |
https://doi.org/10.1186/s12891-019-2821-8 |
container_title |
BMC Musculoskeletal Disorders |
container_volume |
20 |
container_issue |
1 |
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1766220126536859648 |