Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population
Source at https://doi.org/10.1371/journal.pone.0218511. Background : Use of hormonal contraceptives has been associated with Staphylococcus aureus nasal carriage in adult women. However, the role of hormonal contraceptives in S. aureus colonization among adolescents and associations with progestin o...
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ftunivtroemsoe:oai:munin.uit.no:10037/16294 2023-05-15T18:34:42+02:00 Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population Stensen, Dina Benedicte Berg Småbrekke, Lars Olsen, Karina Grimnes, Guri Nielsen, Christopher Sivert Simonsen, Gunnar Skov Sollid, Johanna U. E. Furgberg, Anne-Sofie 2019-07-05 https://hdl.handle.net/10037/16294 https://doi.org/10.1371/journal.pone.0218511 eng eng Public Library of Science Stensen, D.B.B. (2022). Sex-steroids and social network in relation to Staphylococcus aureus nasal carriage. (Doctoral thesis). https://hdl.handle.net/10037/24401 . PLoS ONE https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218511 Stensen, D. Småbrekke, L., Olsen, K., Grimnes, G., Nielsen, C.S., Simonsen, G.S. . Furberg, A-S. (2019). Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population. PLoS ONE, 14 (7): e0218511. https://doi.org/10.1371/journal.pone.0218511 FRIDAID 1712175 doi:10.1371/journal.pone.0218511 1932-6203 https://hdl.handle.net/10037/16294 openAccess VDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710 VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710 Journal article Tidsskriftartikkel Peer reviewed 2019 ftunivtroemsoe https://doi.org/10.1371/journal.pone.0218511 2022-03-16T23:58:04Z Source at https://doi.org/10.1371/journal.pone.0218511. Background : Use of hormonal contraceptives has been associated with Staphylococcus aureus nasal carriage in adult women. However, the role of hormonal contraceptives in S. aureus colonization among adolescents and associations with progestin only contraceptives are unknown. Methods : We obtained nasal and throat swab samples from 439 girls aged 17–21 years in the population-based Tromsø study Fit Futures, 2012–2013, Norway, with information on lifestyle, health and biomarkers. We used multivariable logistic regression to study the association between use of hormonal contraceptives and Staphylococcus aureus carriage while adjusting for potential confounding factors. Results : Staphylococcus aureus nasal carriage prevalence were 34%, 42%, and 61% among progestin-only users, non-users, and progestin-estrogen combination contraceptive users, respectively (P<0.001). Use of combination contraceptives doubled the odds of nasal carriage (non-users reference; OR = 2.31, 95%CI = 1.43–3.74). The OR of nasal carriage was 0.29 among progestin-only users compared to combination contraceptives users (95% CI = 0.12–0.67). Discussion : In this study, use of combination hormonal contraceptives was associated with higher risk of Staphylococcus aureus nasal carriage in adolescent girls. Experimental design studies are needed to establish the role of exogenous sex steroids in Staphylococcus aureus colonization in women. Article in Journal/Newspaper Tromsø University of Tromsø: Munin Open Research Archive Norway Tromsø PLOS ONE 14 7 e0218511 |
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Open Polar |
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University of Tromsø: Munin Open Research Archive |
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ftunivtroemsoe |
language |
English |
topic |
VDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710 VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710 |
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VDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710 VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710 Stensen, Dina Benedicte Berg Småbrekke, Lars Olsen, Karina Grimnes, Guri Nielsen, Christopher Sivert Simonsen, Gunnar Skov Sollid, Johanna U. E. Furgberg, Anne-Sofie Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population |
topic_facet |
VDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710 VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710 |
description |
Source at https://doi.org/10.1371/journal.pone.0218511. Background : Use of hormonal contraceptives has been associated with Staphylococcus aureus nasal carriage in adult women. However, the role of hormonal contraceptives in S. aureus colonization among adolescents and associations with progestin only contraceptives are unknown. Methods : We obtained nasal and throat swab samples from 439 girls aged 17–21 years in the population-based Tromsø study Fit Futures, 2012–2013, Norway, with information on lifestyle, health and biomarkers. We used multivariable logistic regression to study the association between use of hormonal contraceptives and Staphylococcus aureus carriage while adjusting for potential confounding factors. Results : Staphylococcus aureus nasal carriage prevalence were 34%, 42%, and 61% among progestin-only users, non-users, and progestin-estrogen combination contraceptive users, respectively (P<0.001). Use of combination contraceptives doubled the odds of nasal carriage (non-users reference; OR = 2.31, 95%CI = 1.43–3.74). The OR of nasal carriage was 0.29 among progestin-only users compared to combination contraceptives users (95% CI = 0.12–0.67). Discussion : In this study, use of combination hormonal contraceptives was associated with higher risk of Staphylococcus aureus nasal carriage in adolescent girls. Experimental design studies are needed to establish the role of exogenous sex steroids in Staphylococcus aureus colonization in women. |
format |
Article in Journal/Newspaper |
author |
Stensen, Dina Benedicte Berg Småbrekke, Lars Olsen, Karina Grimnes, Guri Nielsen, Christopher Sivert Simonsen, Gunnar Skov Sollid, Johanna U. E. Furgberg, Anne-Sofie |
author_facet |
Stensen, Dina Benedicte Berg Småbrekke, Lars Olsen, Karina Grimnes, Guri Nielsen, Christopher Sivert Simonsen, Gunnar Skov Sollid, Johanna U. E. Furgberg, Anne-Sofie |
author_sort |
Stensen, Dina Benedicte Berg |
title |
Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population |
title_short |
Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population |
title_full |
Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population |
title_fullStr |
Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population |
title_full_unstemmed |
Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population |
title_sort |
hormonal contraceptive use and staphylococcus aureus nasal and throat carriage in a norwegian youth population |
publisher |
Public Library of Science |
publishDate |
2019 |
url |
https://hdl.handle.net/10037/16294 https://doi.org/10.1371/journal.pone.0218511 |
geographic |
Norway Tromsø |
geographic_facet |
Norway Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
Stensen, D.B.B. (2022). Sex-steroids and social network in relation to Staphylococcus aureus nasal carriage. (Doctoral thesis). https://hdl.handle.net/10037/24401 . PLoS ONE https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218511 Stensen, D. Småbrekke, L., Olsen, K., Grimnes, G., Nielsen, C.S., Simonsen, G.S. . Furberg, A-S. (2019). Hormonal contraceptive use and Staphylococcus aureus nasal and throat carriage in a Norwegian youth population. PLoS ONE, 14 (7): e0218511. https://doi.org/10.1371/journal.pone.0218511 FRIDAID 1712175 doi:10.1371/journal.pone.0218511 1932-6203 https://hdl.handle.net/10037/16294 |
op_rights |
openAccess |
op_doi |
https://doi.org/10.1371/journal.pone.0218511 |
container_title |
PLOS ONE |
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14 |
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7 |
container_start_page |
e0218511 |
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